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ZSA Wrap up CVRM

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ZSA Wrap up CVRM

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ZSA Wrap up CVRM
Welke risicoscore(s) mag/mogen worden gebruikt?
1. Wat is het risico volgens deze scores? Kijk bij de QRISK score zowel naar het absolute als
het relatieve risico en bereken met behulp van U-prevent ook het levenslange risico (DIAL,
SMART reach of Life-CVD model).
2. Waardoor worden eventuele discrepanties tussen QRISK, SCORE en Framingham
veroorzaakt?
1. Framingham and QRISK di er in their endpoints. Framingham includes angina as
well as the de nite endpoints of CHD events or stroke, while QRISK relies on the
accuracy of primary care cardiovascular risk registers for its endpoints, which includes
transient ischaemic attacks (TIAs).
3. Wat is op grond van de verschillende risicoscores het behandelplan (gebruik voor het
behandeladvies de Nederlandse richtlijn CVRM)?
4. Benoem het belangrijkste voor en nadeel van een score die gebaseerd is op het absolute
risico, het relatieve risico en het lifetime risico.
1. Absoluut risico: voordeel; speci ek voor deze persoon
2. Relatief risico: nadeel; moeilijk te begrijpen, neemt prevalentie niet me
3. Life time: nadeel: weinig korte termijn winst + langdurige behandeling

Vignet 1
Een 65-jarige niet-rokende vrouw van Nederlandse afkomst met een bloeddruk van 160/100
mmHg en een totaal cholesterol van 6.0 mmol/L, een HDL van 1.0 mmol/L en een LDL van 3.5
mmol/L. De BMI is 25 kg/m2 (lengte 1.70, gewicht 72 kg).

1. QRISK: 10 jaar risico heart attack of beroerte = 13,9%. RR = 1,8.
2. Framingham: 10,7%
3. U-prevent: 10 jaars = 7,3%. Levenslang = 45,6%


Volgens CVRM NHG heeft deze mevrouw een oranje / matig risico (leeftijd, hoge bloeddruk, hoog
cholesterol) = 5-9% kans op sterfte + ziekte HVZ. —> leefstijladviezen, mogelijk in combinatie met
medicamenteus beleid
1. Bewegen
2. BMI 20-25
3. Niet roken, minimaal drinken
4. Statine + antihypertensiva: Diuretica, ACE-remmers, ARB’s, calciumantagonisten OF
bètablokkers





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