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Samenvatting VOLLEDIG OVERZICHT BEHANDELINGEN REUMATOLOGIE

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Een volledig en duidelijk overzicht van verschillende reumatologische behandelingen die kunnen overlappen/licht verschillen. Subtiele verschillen staan duidelijk aangegeven.

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MSK – Reumatologie – Behandelingen
Spondyloartritis
- Fysieke activiteit en sportbeoefening
- NSAIDs
- Anti-TNF (etanercept, adalimumab, infliximab, golimumab,
certolizumab)
Spondyloartritis
- Anti-IL17 (ixekizumab)
- JAK-inhibitoren (tofacitinib)

DMARDs werken niet goed op de rug. Anti-IL23 werkt ook niet voor SpA!
- NSAID en/of intra-articulaire corticosteroïden
- Sulfasalazine
Reactieve artritis
- Antibiotica tegen primaire infectie
- Anti-TNF? (niet terugbetaald)
- NSAID en eventueel intra-articulaire glucocorticoïden
- Methotrexaat (of leflunomide/sulfasalazine bij contra-indicatie)
- Anti-TNF (etanercept, adalimumab, infliximab, golimumab,
certolizumab)
o Etanercept: werkt minder op de huid
- Anti-IL12/23 (ustekinumab)
Psoriasis artritis - Anti-IL17 (ixekizumab)
- PDE4-inhibitor (apremilast)
- JAK-inhibitoren (tofacitinib)
- Anti-IL23 (guselkumab)

Geen klassieke DMARDs indien ook axiale aantasting.
Anti-IL17 niet bij Crohn: kan zelfs heropflakkering geven.
Gastro-intestinale problematiek:
- Corticosteroïden
- 5-ASA, azathioprine
- Anti-TNF (etanercept, adalimumab, infliximab, golimumab,
certolizumab)
o Etanercept: werkt niet goed op de darm
- Anti-IL12/23 (ustekinumab)
IBD artritis
Articulaire problematiek:
- NSAID (opletten met opstoten colitis!)
- Salazopyrine
- Anti-TNF (etanercept, adalimumab, infliximab, golimumab,
certolizumab)
o Etanercept: werkt niet goed op de darm

JAK-inhibitoren zijn naast deze zaken ook mogelijk voor IBD.

1

, Detail:
- Anti-IL17 werkt goed voor SpA maar kan Crohn verergeren
- Anti-IL23 is goed voor de darm en huid maar werkt niet hgoed bij SpA.




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Uploaded on
June 14, 2022
Number of pages
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Written in
2021/2022
Type
SUMMARY

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