EPITHELIUM TISSUE
DEPARTMENT OF ANATOMY
, Four Basic Types of Tissue
• Epithelia
• Connective tissue
• Muscle tissue
• Nervous tissue
2
, Cell-to-cell Adhesions
• Cell adhesion is the binding of a cell to a surface, such as
an extracellular matrix or another cell
• Cellular adhesion is essential in maintaining multi-cellular
structure.
• Adhesion
molecules
– Glycoproteins
bind cells
together
– Intercellular
proteoglycans
glue cells together
– Calcium ions play
an important
role
3
, Cell-to-cell Adhesion types
• Cell junctions
– Zonula
occludens
– Zonula
adherens
– Fascia
adherens
– Macula
adherens
(Desmosome)
– Gap junction
(Nexus)
– Hemidesmoso
me
4
DEPARTMENT OF ANATOMY
, Four Basic Types of Tissue
• Epithelia
• Connective tissue
• Muscle tissue
• Nervous tissue
2
, Cell-to-cell Adhesions
• Cell adhesion is the binding of a cell to a surface, such as
an extracellular matrix or another cell
• Cellular adhesion is essential in maintaining multi-cellular
structure.
• Adhesion
molecules
– Glycoproteins
bind cells
together
– Intercellular
proteoglycans
glue cells together
– Calcium ions play
an important
role
3
, Cell-to-cell Adhesion types
• Cell junctions
– Zonula
occludens
– Zonula
adherens
– Fascia
adherens
– Macula
adherens
(Desmosome)
– Gap junction
(Nexus)
– Hemidesmoso
me
4