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Bio 101 Notes Mutation And Variation

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Bio 101 Notes MUTATION AND VARIATION CUT OBJECTIVE 26!!! NON-MENDELIAN INHERITANCE - Mendelian = Complete Dominance - Only the dominant allele’s protein is produced - When a yellow and purple parent produce a purple offspring - Not all traits are simply determined by a single dominant and a single recessive allele. - Incomplete Dominance (see Diana’s picture) - A little of each allele’s protein is produced. - Codominance - A lot of each allele’s protein is produced. - Polygenic - Multiple genes determine the trait - Eye color - Bell Peppers - Colon Cancer - Human needs to have mutations in about 7 different genes. - Sex-Linked Traits - Gene for trait is on portion of “X” chromosomes not matched by “Y” COMPLEXITY - Variable Expression: All cells in an organism have the same genes, but only some are used. - Muscle Cell - Pancreatic Cell - Molecular “bookmarks” are put in each cell’s DNA to indicate which genes should be active. - Modifier Genes: Some genes can modify the effect of another gene. - Albino: Gene stops production of pigment proteins - Master Control Genes: Activate numerous genes to control complex tasks - Environmental Effects: A cell’s surroundings can impact how genes function - Diet and hormones - Which is a bigger influence: Genetics or Environment? (Nature vs Nurture) - Heterochromia: your eye has 2 distinct color

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A&P 2 Lab 5- Blood Types

Key Terms

 ● Antigen- protein, glycoprotein, or glycolipid. Genetically unique to
each individual except identical twins. Found on surface of red blood
cells and determine what blood type we have. Help the body
distinguish foreign matter that enters blood stream. If someone does
not have any antigens, they are type O.

 ● Antibody- bind to antigens present on red blood cells and mark
them for destruction. They are found in the blood plasma. They will
only attack if they detect foreign matter, they will not attack your own
red blood cells.

 ● Agglutinogen- an antigen that stimulates the production of an
agglutinin.

 ● Agglutinin- an antibody, lectin, or other substance that causes
agglutination.

 ● Alpha- Agglutinin- is a highly N-glycosylated protein of
approximately 250 kDa. ... By carboxy terminal shortening of the
alpha-agglutinin gene and by replacing three of its eight histidyl
residues by arginine, the active region of alpha-agglutinin for
interaction with alpha-agglutinin has been defined.

 ● Beta- Agglutinin-

 ● Agglutination- the process that occurs if an antigen is mixed with its
corresponding antibody called isoagglutinin. This term is commonly
used in blood grouping. ... The clumping of cells such as bacteria or red
blood cells in the presence of an antibody or complement.

 ● Hemoglobin- A protein inside red blood cells that carries oxygen
from the lungs to tissues and organs in the body and carries carbon
dioxide back to the lungs.

 ● RH Factor- an antigen occurring on the red blood cells of many
humans (around 85 percent) and some other primates. It is particularly
important as a cause of hemolytic disease of the newborn and of
incompatibility in blood transfusions.




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