NSG 6320 AGNP Board Exam – Sexually Transmitted Diseases Prescription

NSG 6320 AGNP Board Exam – Sexually Transmitted Diseases Prescription 1. Question: Which of the following is NOT recommended as an alternative treatment for bacterial vaginosis? Intramuscular ceftriaxone (Rocephin) Correct Clindamycin (Cleocin) vaginal cream Metronidazole (Flagyl) vaginal cream Tinidazole (Tindamax) orally Explanation: Intramuscular ceftriaxone (Rocephin) is not indicated in the treatment of bacterial vaginosis. Metronidazole (Flagyl) vaginal cream may be used if metronidazole oral is ineffective or not well tolerated. Alternative regimens include several tinidazole regimens or clindamycin (oral or intravaginal). 2. Question: The recommended empiric treatment of pelvic inflammatory disease is: penicillin G benzathine (Bicillin) intramuscularly plus ceftriaxone (Rocephin) intramuscularly. azithromycin (Zithromax) orally plus ceftriaxone (Rocephin) intramuscularly. ceftriaxone (Rocephin) intramuscularly plus doxycycline (Vibramycin). Correct metronidazole (Flagyl) plus ofloxacin (Floxin). Explanation: The recommended empiric treatment for mild to moderate symptoms of pelvic inflammatory disease (PID) is ceftriaxone (Rocephin) 250 mg intramuscularly plus doxycycline (Vibramycin) 100 mg twice daily x 14 days with or without metronidazole (Flagyl) 500 mg PO twice daily x 14 days. All regimens used to treat PID should also be effective against Neisseria gonorrhoeae and Chlamydia trachomatis because negative endocervical screening for these organisms does not rule out upper-reproductive tract infection. 3. Question: For the treatment of chlamydia, azithromycin (Zithromax) should be given: as one-time dose. Correct daily for 3 days. daily for 5 days. daily for 7 days. Explanation: For the treatment of chlamydia, azithromycin (Zithromax) should be given as a single dose, 1 gram orally. Azithromycin (Zithromax) is classified as a macrolide. It is active against most isolates of Chlamydia trachomatis, Neisseria gonorrhoeae, and Streptococcus pneumoniae. 4. Question: Clindamycin (Cleocin) to treat bacterial vaginosis should NOT be used in combination with: atorvastatin. prednisone. estradiol. Correct ibuprofen. Explanation: Clindamycin (Cleocin) may decrease hormonal contraceptive efficacy and should not be coadministered with estradiol. The other choices are not known to cause drug-drug interactions when administered with clindamycin. 5. Question: When treating latent syphilis, treatment outcomes do NOT include the prevention of: asymptomatic progression of the disease. neurosyphilis. sexual transmission. Correct transfer to a fetus in pregnancy. Explanation: Because latent syphilis is not transmitted sexually, the objective of treating patients in this stage of disease is to prevent complications (neurosyphilis and progression of disease) and transmission from a pregnant woman to her fetus. 6. Question: The most commonly reported side effects of azithromycin (Zithromax) for treatment of chlamydia are: alopecia and headache. blurred vision and tinnitus. diarrhea and nausea. Correct dry mouth and tachycardia. Explanation: The most common treatment-related side effects of azithromycin (Zithromax) are related to the gastrointestinal system with diarrhea/loose stools, nausea, and abdominal pain. Most of the adverse reactions leading to discontinuation were related to the gastrointestinal tract. Potentially serious adverse reactions of angioedema and cholestatic jaundice have been reported. 7. Question: The most common reason for persistent gonococcal infections is: inappropriate prescribing of the correct treatment regimen. treatment failure due to high resistance rates. failure of the patient to abstain from unprotected sexual intercourse. Correct lack of test-of-cure and follow-up after treatment. Explanation: A high prevalence of Neisseria gonorrhoeae infection has been observed among men and women previously treated for gonorrhea. Rather than signaling treatment failure, most of these infections result from reinfection cau