NSG 3370 WEEK 7 PART 1 DISCUSSION
You are at the local mall and you see a patient who appears to be homeless by his physical
appearance and you witness the person “walk 50 feet to a table sit down, and after 5 seconds he
gets up and walks to a tree and urinates on it” He repeats this action 5 times apparently oblivious
to his surroundings. When the police come he ignores them as if they aren’t there. Later, you go
to work and sitting in exam room 3 is the same person! Now, he is your patient, when you talk to
him he has no recollection of his behavior by the mall.
• What is your differential diagnosis?
• What tests do you order?
• An MRI comes back and there seems to be a lesion in the temporal lobe does this change
your differential? The EEG also comes back with unusual excitatory activity. What is
your definitive diagnosis? In retrospect did anything bias your first differential?
This case study is complex due to little information on the patient. The only information to assist
in making a differential diagnosis is assuming he is homeless due to his physical appearance, his
repetitive state of mind and oblivious to his surroundings, and now the patient is unaware of his
actions. Several differential diagnosis comes to mind. Such information to assist in making a
definitive diagnosis would be the patient’s age and history of his past medical, family, and social.
Assuming this patient is homeless, many factors aid in his behaviour. Differential diagnosis are
as follows:
Traumatic Brain Injury
Mental Illness
Korsakoff syndrome
Traumatic brain injury (TBI) can be caused by many factors such as falls, motor vehicle
accidents, and assaults. Short term and long term deficits can alter neurological function that are
caused by direct blow to the head. TBI is defined as a “blow or jolt to the head or a penetrating
head injury that disrupts the [normal] function of the brain” (Anderson et al., 2014, p. 2210). The
pathological aspect of TBI depends on the structural changes from head injury whether open or
closed; damage to the cortical tissue; and hematoma formation that can damage subcortical
structures leading to ischemia (Mott, McConnon, & Rieger (2012). Considering the patient
exhibits no open head injury, the assumption is he possibly is suffering from closed head injury
due to trauma/blow to the head. With a closed head injury, the frontal and temporal lobes are
predominantly susceptible for severe damage (Anderson et al., 2014). TBI symptoms depending
on severity of damage can affect concentration, fatigue, memory lapse, confusion, and difficulty
sleeping. Along with TBI there may also be impaired decision making and the ability to solve
problems (Anderson et al., 2014). The prevalence of TBI among homeless men is high with poor
physical and mental outcomes observed (Anderson et al., 2014).
Mental illness is common among homeless persons with many experiencing depression, anxiety,
bipolar disorder, and/or schizophrenias; all lead to acute incidences of confusion, impaired
though process, and inhibit ability to solve problems (Stergiopoulos et al., 2015). With chemical
imbalances and genetic disorders which affect psychological and cognitive functions may be the
result of this patient’s behaviour. Further tests and additional information on his H & P could
clarify the significance of mental illness. The cause of mental illness is unknown, though a
combination of factors such as biological, environmental, and psychological can contribute and
alter one’s mental stability. Nerve cells within the brain communicate through chemicals via
neurotransmitters. Medications maybe given to assist in balancing out the chemical and genetic
proportions of the brain. Injury to the brain may also be a factor to mental illness disrupting the
neurotransmitters (Stergiopoulos et al., 2015). This patient may have some degree of mental
illness whether biological, environmental, and/or simply genetic. According to Anderson et al.
(2014) majority of those persons who are homeless are due to mental health.
Anderson et al. (2014) stated in their research “neuropsychological assessment of homeless
persons tends to be scarce or absent, often due to limited personnel trained in assessment and
inadequate financial resources within shelters” (p. 2211). Many studies have found that
homelessness is related with higher incidence of mental illness, depression, substance abuse of
drugs and alcohol, and behaviour issues (Anderson et al., 2014). “The Health Care for the
Homeless Clinicians Network indicates that severe cognitive impairments resulting from TBI are
sometimes misdiagnosed as schizophrenia” thus resulting in inappropriate treatment and
medication regimen (Anderson et al., 2014, p. 2211).
Korsakoff syndrome is a disorder with an acute onset of confusion, nystagmus,
ophthalmoplegia, and ataxia due to thiamine deficiency. Alcoholism may contribute to the
inadequate intake of thiamin, but Wernicke encephalopathy can lead to other conditions such as
head injury, starvation, cancer, and AIDS (O’Malley & O’Malley, 2016). Increase intake of
alcohol can disrupt the function of cells within the brain. Thiamine is an important co-factor for
enzymes that break down lipids and carbohydrates in the brain and support in the making of
amino acids; without thiamine to breakdown glucose, the brain function becomes impaired
(McCance, Huether, Brashers, & Rote, 2013). Clinical symptoms of Korsakoff syndrome maybe
mood changes, disorientation, memory lapse, the inability to recall new information, disruption
of thought process, and confusion (O’Malley & O’Malley, 2016).
Tests to order:
To determine appropriate diagnosis, a CT and MRI of the head to determine the extent of brain
injury or any neurological dysfunction. Labs such as CBC, BMP, liver and renal function, VitB12, thiamin, and niacin serum levels, and alcohol and drug screen should be tested. Further
questioning the patient of his past medical history and/or family history. Along with physical and
neurological assessment.
An MRI comes back and there seems to be a lesion in the temporal lobe does this change
your differential? The EEG also comes back with unusual excitatory activity. What is your
definitive diagnosis? In retrospect did anything bias your first differential?
This does not change my differential due to the information given in this case study. A lesion and
excitatory activity can be related to trauma within the brain. The patient being homeless puts him
at risk for TBI due to harsh elements of the environment. No, nothing biased me from my
differential. With research, it’s noted that homeless people are at risk for TBI and many exhibit
some form of mental health issue (Anderson et al., 2014). Just because the patient is homeless
does not change the fact he should be treated just as any other patient who comes through the ED
with TBI, mental illness, or who may have ETOCH issues.
Anderson, J., Kot, N., Ennis, N., Colantonio, A., Ouchterlony, D., Cusimano, M. D., &
Topolovec-Vranic, J. (2014). Traumatic brain injury and cognitive impairment in men
who are homeless. An International Multidisciplinary Journal, 36(26), . doi:
10.3109/.2014.
McCance, K. L., Huether, S. E., Brashers, V. L., & Rote, N. S. (2013). Pathophysiology: The
biologic basis for disease in adults and children. (7th ed.). St. Louis, MO: Mosby
Mott, T. F., McConnon, M. L., & Rieger, B. P. (2012). Subacute to chronic mild traumatic brain
injury. American Family Physician, 86(11), .
O’Malley, G. F. & O’Malley, R. (2016). Wernicke encephalopathy. Retrieved from:
Stergiopoulos, V., Cusi, A., Bekele, T., Skosireva, A., Latimer, E., Schultz, C…Rourke, S. B.
(2015). Neurocognitive impairment in large sample of homeless adults with mental
illness. Acta Psychiatrica Scandinavica, 131, 256-268. doi: 10.1111/acps.1239
Content preview
NSG 3370 WEEK 7 PART 1 DISCUSSION
You are at the local mall and you see a patient who appears to be homeless by his physical
appearance and you witness the person “walk 50 feet to a table sit down, and after 5 seconds he
gets up and walks to a tree and urinates on it” He repeats this action 5 times apparently oblivious
to his surroundings. When the police come he ignores them as if they aren’t there. Later, you go
to work and sitting in exam room 3 is the same person! Now, he is your patient, when you talk to
him he has no recollection of his behavior by the mall.
• What is your differential diagnosis?
• What tests do you order?
• An MRI comes back and there seems to be a lesion in the temporal lobe does this change
your differential? The EEG also comes back with unusual excitatory activity. What is
your definitive diagnosis? In retrospect did anything bias your first differential?
This case study is complex due to little information on the patient. The only information to assist
in making a differential diagnosis is assuming he is homeless due to his physical appearance, his
repetitive state of mind and oblivious to his surroundings, and now the patient is unaware of his
actions. Several differential diagnosis comes to mind. Such information to assist in making a
definitive diagnosis would be the patient’s age and history of his past medical, family, and social.
Assuming this patient is homeless, many factors aid in his behaviour. Differential diagnosis are
as follows:
Traumatic Brain Injury
Mental Illness
Korsakoff syndrome
Traumatic brain injury (TBI) can be caused by many factors such as falls, motor vehicle
accidents, and assaults. Short term and long term deficits can alter neurological function that are
caused by direct blow to the head. TBI is defined as a “blow or jolt to the head or a penetrating
head injury that disrupts the [normal] function of the brain” (Anderson et al., 2014, p. 2210). The
pathological aspect of TBI depends on the structural changes from head injury whether open or
closed; damage to the cortical tissue; and hematoma formation that can damage subcortical
structures leading to ischemia (Mott, McConnon, & Rieger (2012). Considering the patient
exhibits no open head injury, the assumption is he possibly is suffering from closed head injury
due to trauma/blow to the head. With a closed head injury, the frontal and temporal lobes are
predominantly susceptible for severe damage (Anderson et al., 2014). TBI symptoms depending
on severity of damage can affect concentration, fatigue, memory lapse, confusion, and difficulty
sleeping. Along with TBI there may also be impaired decision making and the ability to solve