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Week 1 Case Study: Coagulation
Chamberlain University
BIOS 255-13465
, 2
Discuss which clotting factors the PT and PTT test evaluate
and whether each test measures the intrinsic or the
extrinsic pathways.
According to this website, “The PTT assesses the amount and the function of
certain proteins in the blood called coagulation or clotting factors that are an
important part of blood clot formation” (Expert Board, 2021). The clotting factors for
a PT test include VII, X, V, II, and I (fibrinogen). This test measures the extrinsic
pathways. As for PTT, this test evaluates factors XII, XI, VIII, IX and measures
intrinsic pathways.
Describe the common coagulation pathway.
The common coagulation pathway consists of a series of events that all lead up to
hemostasis. The two paths known as extrinsic and intrinsic, happen at separate times
but come together at a certain point leading to fibrin activation. The common pathway
factors consist of factors I, II, V, VIII, X. This pathway begins at factor X, which is
then activated to factor XA. Once XA is activated, prothrombin and then thrombin are
activated.
Based on Jessie’s test, which factor deficiency do you
believe he has and why?
Week 1 Case Study: Coagulation
Chamberlain University
BIOS 255-13465
, 2
Discuss which clotting factors the PT and PTT test evaluate
and whether each test measures the intrinsic or the
extrinsic pathways.
According to this website, “The PTT assesses the amount and the function of
certain proteins in the blood called coagulation or clotting factors that are an
important part of blood clot formation” (Expert Board, 2021). The clotting factors for
a PT test include VII, X, V, II, and I (fibrinogen). This test measures the extrinsic
pathways. As for PTT, this test evaluates factors XII, XI, VIII, IX and measures
intrinsic pathways.
Describe the common coagulation pathway.
The common coagulation pathway consists of a series of events that all lead up to
hemostasis. The two paths known as extrinsic and intrinsic, happen at separate times
but come together at a certain point leading to fibrin activation. The common pathway
factors consist of factors I, II, V, VIII, X. This pathway begins at factor X, which is
then activated to factor XA. Once XA is activated, prothrombin and then thrombin are
activated.
Based on Jessie’s test, which factor deficiency do you
believe he has and why?
