NSG 6005 FINAL EXAM 1 – QUESTION WITH
ANSWERS
The U.S. Food and Drug Administration (FDA) regulates:
The official labeling for all prescriptions and over-the-counter drugs
Nurse practitioner prescriptive authority is regulated by:
The State Board of Nursing for each state
Electronic health records (EHRs)
Allow for all patient data to be centralized in one location for access by multiple providers
Alterations in drug metabolism among Asians may lead to
Slower metabolism of antidepressants, requiring lower doses
Pharmacokinetics among Asians are universal to all the Asian ethnic groups.
B. False
Gender differences between men and women in pharmacokinetics include:
Higher proportion of body fat so that lipophilic drugs have relatively greater volumes of
distribution
The factor that has the greatest effect on males developing male sexual characteristics is:
Androgen production
An advantage of prescribing a sublingual medication is that the medication is:
A. Absorbed rapidly
Infants and young children are at higher risk of ADRs due to:
B. Lack of safety and efficacy studies in the pediatric population
Pharmacokinetic factors that affect prescribing include:
C. Bioavailability
Carbamazepine has a Black Box warning recommending testing for the HLA-B*1502 allele in
patients with Asian ancestry prior to starting therapy due to:
C. Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele
Genetic polymorphisms account for differences in metabolism, including:
D. All of the above
A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):
A. Cytotoxic hypersensitivity reaction
The elderly are at high risk of ADRs due to:
, D. Age-related decrease in renal function
The time required for the amount of drug in the body to decrease by 50% is called:
Half-life
The angiotensin converting enzyme (ACE) inhibitor lisinopril is a known teratogen. Teratogens
cause Type ____ ADR
D
Common OTC pain relievers such as acetaminophen or ibuprofen:
Are harmful if taken in higher than recommended amounts
A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to
prescribing because:
Distribution of drugs to target tissue may be affected
Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:
Decreased response to warfarin
The first step in the prescribing process according to the World Health Organization is:
C.
Diagnosing the patient’s problem
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because:
A six-year-old may have problems swallowing a pill
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
C
Onset of Action
When obtaining a drug history from Harold, he gives you a complete list of his prescription
medications. He denies taking any other drugs, but you find that he occasionally takes aspirin for
his arthritis flare-ups. This is an example of
A common misconception that intermittently taken OTC medications are not an important part of
his drug history
Which one of the following statements about bioavailability is true?
*Bioavailability issues are especially important for drugs with narrow therapeutic ranges
or sustained release mechanisms
All brands of a drug have the same bioavailability
Drugs that are administered more than once a day have a greater bioavailability than drugs given
once daily
Combining an active drug with an inert substance does not affect bioavailability
Beta blockers treat hypertension because they:
Reduce peripheral resistance
ANSWERS
The U.S. Food and Drug Administration (FDA) regulates:
The official labeling for all prescriptions and over-the-counter drugs
Nurse practitioner prescriptive authority is regulated by:
The State Board of Nursing for each state
Electronic health records (EHRs)
Allow for all patient data to be centralized in one location for access by multiple providers
Alterations in drug metabolism among Asians may lead to
Slower metabolism of antidepressants, requiring lower doses
Pharmacokinetics among Asians are universal to all the Asian ethnic groups.
B. False
Gender differences between men and women in pharmacokinetics include:
Higher proportion of body fat so that lipophilic drugs have relatively greater volumes of
distribution
The factor that has the greatest effect on males developing male sexual characteristics is:
Androgen production
An advantage of prescribing a sublingual medication is that the medication is:
A. Absorbed rapidly
Infants and young children are at higher risk of ADRs due to:
B. Lack of safety and efficacy studies in the pediatric population
Pharmacokinetic factors that affect prescribing include:
C. Bioavailability
Carbamazepine has a Black Box warning recommending testing for the HLA-B*1502 allele in
patients with Asian ancestry prior to starting therapy due to:
C. Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele
Genetic polymorphisms account for differences in metabolism, including:
D. All of the above
A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):
A. Cytotoxic hypersensitivity reaction
The elderly are at high risk of ADRs due to:
, D. Age-related decrease in renal function
The time required for the amount of drug in the body to decrease by 50% is called:
Half-life
The angiotensin converting enzyme (ACE) inhibitor lisinopril is a known teratogen. Teratogens
cause Type ____ ADR
D
Common OTC pain relievers such as acetaminophen or ibuprofen:
Are harmful if taken in higher than recommended amounts
A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to
prescribing because:
Distribution of drugs to target tissue may be affected
Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:
Decreased response to warfarin
The first step in the prescribing process according to the World Health Organization is:
C.
Diagnosing the patient’s problem
A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because:
A six-year-old may have problems swallowing a pill
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
C
Onset of Action
When obtaining a drug history from Harold, he gives you a complete list of his prescription
medications. He denies taking any other drugs, but you find that he occasionally takes aspirin for
his arthritis flare-ups. This is an example of
A common misconception that intermittently taken OTC medications are not an important part of
his drug history
Which one of the following statements about bioavailability is true?
*Bioavailability issues are especially important for drugs with narrow therapeutic ranges
or sustained release mechanisms
All brands of a drug have the same bioavailability
Drugs that are administered more than once a day have a greater bioavailability than drugs given
once daily
Combining an active drug with an inert substance does not affect bioavailability
Beta blockers treat hypertension because they:
Reduce peripheral resistance
