Module I2 ICase IStudy IAP1
• Question I 1
1 Iout Iof I1 Ipoints
Ben Iis Ia I6-month Iold Iinfant Iwho Ihas Ia Ihistory Iof Irespiratory Iinfections. IHis Iparents Iare
Iconcerned Ithat Ihis Isymptoms Iare Iworsening Iand Ibring Ihim Ito Ihis Ipediatrician, IDr.
Johnson. IThey Iexplain Ithat Ihe Ihas Ia Ipersistent Icough Iand Isometimes Icoughs Iup Iphlegm.
IHe Ialso Iexperiences Iperiodic Iwheezing Iand Ishortness Iof Ibreath. IDr. IJohnson Inotes Ithat Ihis
Iweight Iand Iheight Ihave Inot Iincreased Ias Imuch Ias Ipredicted Isince Ihis Ilast Ivisit. IHe Iis
Iconcerned Ithat IBen Imay Ihave Ia Igenetic Icondition Icalled ICystic IFibrosis.
There Iare Iseveral Iways Ito Itest Ifor ICystic IFibrosis. IIn Iyour Iown Iwords,
I briefly I describe I2 Idiagnostic I tests Ithat I Dr. I Johnson I could I useIto
Idetermine Iif IBen Ihas ICystic IFibrosis.
Selected Two Itests Ithat IDr. IJohnson Icould Iuse Iwould Ibe Ia Isnasal Ipotential Idifference Itest, Ior Ia
IAnswer: IsweatItest. IWith Ia Inasal Ipotential Idifference Itest Ithe Idoctor Iwill Icheck Ithe Icells Iin Ihis
Inose Ito Isee Ihow Iwell Ithe Isalt Iis Imoving Iin Iand Iout Iof Ithem. IHe Ican Icheck Ithe Icells Iby
Iusing IelectrodesIon Ithe Ilining Iof Ithe Inose. IIf Ithe Iresults Icome Iback Iabnormal Ithis Icould
Ishow Ipositive Ifor ICystic IFibrosis. IThe Isecond Itest Ithat Ican Ibe Idone Iis Ia Isweat Itest. IThe
Idoctor Iwill Irub Ia Ispecial Ichemical Ithat Icauses Isweating Iand Ithen Iwill Icreate Ia Ismall
Ielectrical Icurrent Ion ItheIarea. IThe Isweat Iwill Ibe Iwiped Ioff Ion Ia Icloth Iand Itaken Ifor
Ianalyzing. ISomeone Iwho Ihas Itoo Imuch Isalt Iin Itheir Isweat Ican Ibe Idiagnosed Iwith ICystic
IFibrosis. IA Ipositive Idiagnosis Iwill Irequire Itwo Ipositive Iresults Iwhere Ithe Itests Iare Idone
Iof Idifferent Idays. Ihttps://www.webmd.com/children/tc/cystic-fibrosis-exams-and-tests#1
Ihttps://www.nhlbi.nih.gov/health-topics/cystic-fibrosis
Respons Nice Ijob...great Iresources Iused Ifor Iresearch.
e
I
IFeedba
cIk:
• Question I2
1 Iout Iof I1 Ipoints
Cystic IFibrosis Iis Ian Iinherited Icondition. IWhich Iof Ithe Ifollowing Idescribes Ithe
Iinheritance Ipattern?
Selected Autosomal
IAnswer: Irecessive
• Question I3
1 Iout Iof I1 Ipoints
List Iat Ileast I3 Iother Isymptoms Iof ICystic IFibrosis Ithat Iare Inot Imentioned Iin Ithe Icase Istudy
Iabout IBen.
Selected Three Iother Isymptoms Iof ICystic IFibrosis Iare Iexercise Iintolerance, Irepeated Ilung
IAnswer: Iinfections, Isevere Iconstipation Ior Ifoul Ismelling Igreasy Istool.
Ihttps://www.mayoclinic.org/diseases-conditions/cystic-fibrosis/symptoms-causes/syc-
I20353700
Response [None I Given]
IFeedback
:
• Question I 4
1 Iout Iof I1 Ipoints
, Which Iof IBen's Iparents Icarried Ithe Idefective Igene Iwhich Icauses ICystic IFibrosis?
Selected Both
IAnswer: IParetn
s
• Question I 5
1 Iout Iof I1 Ipoints
If Iboth Iof IBen’s Iparents Iare ICystic IFibrosis Icarriers Iand Iplan Ito Ihave Ianother Ichild, Iwhat Iare
Ithe Ichances Ithat Itheir Inext Ichild Iwould INOT Ibe Ia Icarrier Iand Iwould INOT Ibe Iaffected Iby
ICystic IFibrosis?
Selected 25
Answer: %
• Question I 6
1 Iout Iof I1 Ipoints
In Iyour Iown Iwords, Ibriefly Idescribe Ihow Ithe ICystic IFibrosis Igene Iaffects Ithe Icell
Imembrane.
Selected The ICystic IFibrosis Igene Iaffects Ithe Ithe Icell Imembrane Iby Icreating Ia Iprotein ICTFR
IAnswer: I(Cystic IFibrosis ITransmembrane IConductance IRegulator) Ithat Iis Imutated. IThis Iprotein
Iis Iin Icells Ithat Inormally Iline Ithe Ilungs, Isweat Iglands, Iand Idigestive Itrack. IWhen Ithis
Iprotein Iis Imutated Iepithelial Icells Ican Ino Ilonger Iregulate Ihow Ichloride Imoves Ithrough
Ithe Icell Imembrane. IThis Icauses Ia Idisruption Iin Iwater Iand Isodium Ibalance Ineeded Ito
Icreate Ithe IthinIlining Iof Imucous Iin Ithe Ilungs, Ipancreas Iand Ipassageways Ito Iother Iorgans.
IWith Ithis Idisruption Iin Ibalance, Ithe Ithin Ilining Ibecomes Ithick, Isticky, Iand Istuck Iin Ithe
Irespiratory Iand Idigestive Isystems.
https://kidshealth.org/en/parents/cf.html
Respons [None I Given]
e
I
IFeedba
cIk:
• Question I7
1 Iout Iof I1 Ipoints
Which Iof Ithe Ifollowing Iis Inot Ia Icommon Itreatment Ifor ICystic IFibrosis?
Selected Frequent Iblood Itransfusions
IAnswer:
• Question I8
1 Iout Iof I1 Ipoints
In Iyour Iown Iwords, Ibriefly Idescribe Iwhy IBen’s Iskin Imay Itaste Isalty.
Selected When IBen Isweats Ithe Isalt Ithat Iis Inot Iproperly Imoving Ithrough Ithe Icells Irise Iup Iwith
IAnswer: ItheIwater Iand Iis Inot Ireabsorbed. IWhen Ithe Isweat Idries Ithe Isalt Iis Istill Ion Ithe Iouter Ilayer
Iof Iskin Iallowing Ihis Iskin Ito Itaste Isalty.
Response [None I Given]
IFeedback
:
• Question I 1
1 Iout Iof I1 Ipoints
Ben Iis Ia I6-month Iold Iinfant Iwho Ihas Ia Ihistory Iof Irespiratory Iinfections. IHis Iparents Iare
Iconcerned Ithat Ihis Isymptoms Iare Iworsening Iand Ibring Ihim Ito Ihis Ipediatrician, IDr.
Johnson. IThey Iexplain Ithat Ihe Ihas Ia Ipersistent Icough Iand Isometimes Icoughs Iup Iphlegm.
IHe Ialso Iexperiences Iperiodic Iwheezing Iand Ishortness Iof Ibreath. IDr. IJohnson Inotes Ithat Ihis
Iweight Iand Iheight Ihave Inot Iincreased Ias Imuch Ias Ipredicted Isince Ihis Ilast Ivisit. IHe Iis
Iconcerned Ithat IBen Imay Ihave Ia Igenetic Icondition Icalled ICystic IFibrosis.
There Iare Iseveral Iways Ito Itest Ifor ICystic IFibrosis. IIn Iyour Iown Iwords,
I briefly I describe I2 Idiagnostic I tests Ithat I Dr. I Johnson I could I useIto
Idetermine Iif IBen Ihas ICystic IFibrosis.
Selected Two Itests Ithat IDr. IJohnson Icould Iuse Iwould Ibe Ia Isnasal Ipotential Idifference Itest, Ior Ia
IAnswer: IsweatItest. IWith Ia Inasal Ipotential Idifference Itest Ithe Idoctor Iwill Icheck Ithe Icells Iin Ihis
Inose Ito Isee Ihow Iwell Ithe Isalt Iis Imoving Iin Iand Iout Iof Ithem. IHe Ican Icheck Ithe Icells Iby
Iusing IelectrodesIon Ithe Ilining Iof Ithe Inose. IIf Ithe Iresults Icome Iback Iabnormal Ithis Icould
Ishow Ipositive Ifor ICystic IFibrosis. IThe Isecond Itest Ithat Ican Ibe Idone Iis Ia Isweat Itest. IThe
Idoctor Iwill Irub Ia Ispecial Ichemical Ithat Icauses Isweating Iand Ithen Iwill Icreate Ia Ismall
Ielectrical Icurrent Ion ItheIarea. IThe Isweat Iwill Ibe Iwiped Ioff Ion Ia Icloth Iand Itaken Ifor
Ianalyzing. ISomeone Iwho Ihas Itoo Imuch Isalt Iin Itheir Isweat Ican Ibe Idiagnosed Iwith ICystic
IFibrosis. IA Ipositive Idiagnosis Iwill Irequire Itwo Ipositive Iresults Iwhere Ithe Itests Iare Idone
Iof Idifferent Idays. Ihttps://www.webmd.com/children/tc/cystic-fibrosis-exams-and-tests#1
Ihttps://www.nhlbi.nih.gov/health-topics/cystic-fibrosis
Respons Nice Ijob...great Iresources Iused Ifor Iresearch.
e
I
IFeedba
cIk:
• Question I2
1 Iout Iof I1 Ipoints
Cystic IFibrosis Iis Ian Iinherited Icondition. IWhich Iof Ithe Ifollowing Idescribes Ithe
Iinheritance Ipattern?
Selected Autosomal
IAnswer: Irecessive
• Question I3
1 Iout Iof I1 Ipoints
List Iat Ileast I3 Iother Isymptoms Iof ICystic IFibrosis Ithat Iare Inot Imentioned Iin Ithe Icase Istudy
Iabout IBen.
Selected Three Iother Isymptoms Iof ICystic IFibrosis Iare Iexercise Iintolerance, Irepeated Ilung
IAnswer: Iinfections, Isevere Iconstipation Ior Ifoul Ismelling Igreasy Istool.
Ihttps://www.mayoclinic.org/diseases-conditions/cystic-fibrosis/symptoms-causes/syc-
I20353700
Response [None I Given]
IFeedback
:
• Question I 4
1 Iout Iof I1 Ipoints
, Which Iof IBen's Iparents Icarried Ithe Idefective Igene Iwhich Icauses ICystic IFibrosis?
Selected Both
IAnswer: IParetn
s
• Question I 5
1 Iout Iof I1 Ipoints
If Iboth Iof IBen’s Iparents Iare ICystic IFibrosis Icarriers Iand Iplan Ito Ihave Ianother Ichild, Iwhat Iare
Ithe Ichances Ithat Itheir Inext Ichild Iwould INOT Ibe Ia Icarrier Iand Iwould INOT Ibe Iaffected Iby
ICystic IFibrosis?
Selected 25
Answer: %
• Question I 6
1 Iout Iof I1 Ipoints
In Iyour Iown Iwords, Ibriefly Idescribe Ihow Ithe ICystic IFibrosis Igene Iaffects Ithe Icell
Imembrane.
Selected The ICystic IFibrosis Igene Iaffects Ithe Ithe Icell Imembrane Iby Icreating Ia Iprotein ICTFR
IAnswer: I(Cystic IFibrosis ITransmembrane IConductance IRegulator) Ithat Iis Imutated. IThis Iprotein
Iis Iin Icells Ithat Inormally Iline Ithe Ilungs, Isweat Iglands, Iand Idigestive Itrack. IWhen Ithis
Iprotein Iis Imutated Iepithelial Icells Ican Ino Ilonger Iregulate Ihow Ichloride Imoves Ithrough
Ithe Icell Imembrane. IThis Icauses Ia Idisruption Iin Iwater Iand Isodium Ibalance Ineeded Ito
Icreate Ithe IthinIlining Iof Imucous Iin Ithe Ilungs, Ipancreas Iand Ipassageways Ito Iother Iorgans.
IWith Ithis Idisruption Iin Ibalance, Ithe Ithin Ilining Ibecomes Ithick, Isticky, Iand Istuck Iin Ithe
Irespiratory Iand Idigestive Isystems.
https://kidshealth.org/en/parents/cf.html
Respons [None I Given]
e
I
IFeedba
cIk:
• Question I7
1 Iout Iof I1 Ipoints
Which Iof Ithe Ifollowing Iis Inot Ia Icommon Itreatment Ifor ICystic IFibrosis?
Selected Frequent Iblood Itransfusions
IAnswer:
• Question I8
1 Iout Iof I1 Ipoints
In Iyour Iown Iwords, Ibriefly Idescribe Iwhy IBen’s Iskin Imay Itaste Isalty.
Selected When IBen Isweats Ithe Isalt Ithat Iis Inot Iproperly Imoving Ithrough Ithe Icells Irise Iup Iwith
IAnswer: ItheIwater Iand Iis Inot Ireabsorbed. IWhen Ithe Isweat Idries Ithe Isalt Iis Istill Ion Ithe Iouter Ilayer
Iof Iskin Iallowing Ihis Iskin Ito Itaste Isalty.
Response [None I Given]
IFeedback
:
