Gluconeogenesis Diagram Study Guide 2021 _ South University

Gluconeogenesis Diagram – 2021 / 2022 Glycerol Fatty acid metabolism (adipose tissue) Dihydroxyacetone phosphate Lactate Exercising skeletal muscle, RBCs Carbon skeleton of some amino acids Glucogenic amino acids (later) substrates for gluconeogenesis Regulated steps require bypass reactions (red Gluconeogenesis is not just boxes) with different enzymes because DG is too reverse glycolysis large and because these are also control points for gluconeogenesis The first step of gluconeogenesis Move pyruvate into the (In the muscle this reaction occurs but only to mitochondria where pyruvate replace TCA cycle intermediates) carboxylase converts it to In liver, kidney, and small intestines where oxaloacetate gluconeogenesis occurs, oxaloacetate can be converted to phosphoenolpyruvate via PEP carboxykinase (part of first step)In liver, oxaloacetate can be converted to kidney, and small intestines phosphoenolpyruvate via PEP carboxykinase where gluconeogenesis occurs, Oxaloacetate can be: depending on what molecule gluconeogenesis is actually starting from Oxaloacetate will EITHER be converted to phosphoenolpyruvate (PEP) OR malate Cannot pass the mitochondrial membrane Oxaloacetate