SBB COMPREHENSIVE EXAM QUESTIONS
AND CORRECT ANSWERS STUDY GUIDE
●● The beta 1-3 linkage between galactose and N-actylglucosamine is
found in:
Answer: Secretions
●● Which of the following represents the Type II chain?
Answer: Beta 1-4 linkage between galactose and N acetyl glucosamine
●● Rank the order of decreasing H concentration on RBCs
Answer: 0>A2>B>A2B>A1>A1B
●● All of the following are genotypes for the A1 phenotype except:
1. A1/A1
2. A1/A2
3. A2/B
4. A1/O
Answer: A2/B
●● The ABO genes are located on which chromosome?
Answer: 9
,●● Which glycosyltransferase is needed before A and B antigens are
formed?
Answer: L-fucosyltransferase
●● What is the typical reaction of the A3 subgroup?
Answer: mixed field reaction with Anti-A and Anti-A,B
●● What is the typical reaction of the Ael subgroup?
Answer: Positive reaction with anti-H
●● What clinical condition may yield positive reactions with Anti-A,
negative with Anti-B, negative with A1 and B cells.
Answer: Hypogammaglobulinemia
●● What differentiates a Bombay anti-H from an anti-H cold agglutin?
Answer: Reactivity at body temperature
●● The is antigen is associated with linear carbohydrate chains?
Answer: i antigen
, ●● The following reactions are found on a 35 yr old male. Anti-A 4+,
Anti-B 0, Anti-A,B-4+, A1 cells 3+, B cells 4+, O cells 3+. How could
these be explained?
Answer: Anti-M in plasma
●● Anti-IH would react best with which RBC?
Answer: O
●● The acquired B phenomenon is only found in which ABO group?
Answer: A
●● Which of the following is true about the A2 subgroup?
1. 1-8% of persons will product anti-A1
2. Anti-A1 does not react with A2 RBCs
3. Anti-A2 is formed
4. Two of the above
Answer: Two of the above (1-8% of persons will product anti-A1 and
Anti-A1 does not react with A2 RBC )
●● Anti-Lu3 is associated with:
Answer: Recessive type Lu(a-b-)
●● The dominant Lu(a-b-) type is associated with what gene?
AND CORRECT ANSWERS STUDY GUIDE
●● The beta 1-3 linkage between galactose and N-actylglucosamine is
found in:
Answer: Secretions
●● Which of the following represents the Type II chain?
Answer: Beta 1-4 linkage between galactose and N acetyl glucosamine
●● Rank the order of decreasing H concentration on RBCs
Answer: 0>A2>B>A2B>A1>A1B
●● All of the following are genotypes for the A1 phenotype except:
1. A1/A1
2. A1/A2
3. A2/B
4. A1/O
Answer: A2/B
●● The ABO genes are located on which chromosome?
Answer: 9
,●● Which glycosyltransferase is needed before A and B antigens are
formed?
Answer: L-fucosyltransferase
●● What is the typical reaction of the A3 subgroup?
Answer: mixed field reaction with Anti-A and Anti-A,B
●● What is the typical reaction of the Ael subgroup?
Answer: Positive reaction with anti-H
●● What clinical condition may yield positive reactions with Anti-A,
negative with Anti-B, negative with A1 and B cells.
Answer: Hypogammaglobulinemia
●● What differentiates a Bombay anti-H from an anti-H cold agglutin?
Answer: Reactivity at body temperature
●● The is antigen is associated with linear carbohydrate chains?
Answer: i antigen
, ●● The following reactions are found on a 35 yr old male. Anti-A 4+,
Anti-B 0, Anti-A,B-4+, A1 cells 3+, B cells 4+, O cells 3+. How could
these be explained?
Answer: Anti-M in plasma
●● Anti-IH would react best with which RBC?
Answer: O
●● The acquired B phenomenon is only found in which ABO group?
Answer: A
●● Which of the following is true about the A2 subgroup?
1. 1-8% of persons will product anti-A1
2. Anti-A1 does not react with A2 RBCs
3. Anti-A2 is formed
4. Two of the above
Answer: Two of the above (1-8% of persons will product anti-A1 and
Anti-A1 does not react with A2 RBC )
●● Anti-Lu3 is associated with:
Answer: Recessive type Lu(a-b-)
●● The dominant Lu(a-b-) type is associated with what gene?
