Sbb Complete Examination Test Questions With Verified Solutions

SBB COMPLETE EXAMINATION TEST
QUESTIONS WITH VERIFIED SOLUTIONS

●● ATP source for RBCs
Answer: 90% from Glycolysis (Embden-Meyerhoff pathway)
10% from pentose phosphate pathway


●● Methemoglobin Reductase Pathway
Answer: necessary to maintain heme iron in ferrous (Fe2+) state
Deficiency causes accumulation of methemoglobin, nonfunctional from
of Hgb


●● Leubering Rapaport Shunt
Answer: permits accumulation of 2,3-DPG


●● "Tense form" of Hgb
Answer: DEOXYGENATED
widening of beta-chain
lower affinity for O2
expels 2,3-DPG


●● "Relaxed form" of Hgb

,Answer: OXYGENATED
beta-chain pulled together
higher affinity for O2
expels 2,3-DPG


●● "Shift Right"
Answer: higher P50 value
decreased pH (increased H+ ion), acidosis
increased 2,3-DPG
higher temperature
high pCO2


Seen in compensated anemia


●● "Shift Left"
Answer: lower P50 value
increased pH (decresed H+ ion), alkalosis
decreasede 2,3-DPG
lower temeratures
low pCO2


Seen in storage of RBC

,●● Type 2 precursor
Answer: Gal-GlcNAc
B1-4


●● Type 1 precursor
Answer: Gal-GlcNAc
B1-3


Secreted (Se, Le)


●● Type 2 H antigen transeferase & Sugar
Answer: FUT-1


Alpha-2-L-fucosyltransferase


Fuctose alpha1-2


●● A antigen transferase & sugar
Answer: D-galactosaminetrasferase


N-acetylgalactosamine alpha1-3

, ●● B antigen transferase & sugar
Answer: D-galacotsyltransferase


galactose alpha1-3


●● Ax subgroup
Answer: weakly positive anti-A
weakly positive anti-A,B


●● Am subgroup
Answer: Negative anti-A
Secretes A & H


●● Ael subgroup
Answer: Negative anti-A
Secretes H only


●● Highest expression of H
Lowest expression of H
Answer: O>A2>B>A2B>A1>A1B> H deficient