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Question 1
Which phase of pharmacokinetics involves the movement of a drug from its site of
administration into the bloodstream?
A) Distribution
B) Absorption
C) Metabolism
D) Excretion
Answer
Answer: B
Rationale
Absorption is the process by which a drug enters the bloodstream from its administration site.
Question 2
A drug that binds to a receptor and produces a maximal response is called a(n):
A) Partial agonist
B) Antagonist
C) Full agonist
D) Inverse agonist
,Answer
Answer: C
Rationale
A full agonist activates the receptor to produce a full biological response.
Question 3
The generic name of a drug is:
A) The name given by the manufacturer
B) The nonproprietary name, often related to the drug’s chemical structure
C) The brand name under which it is marketed
D) A name protected by trademark
Answer
Answer: B
Rationale
Generic names are standardized and used internationally; brand names are proprietary.
Question 4
Which schedule of controlled substances has the highest potential for abuse and no accepted
medical use?
A) Schedule II
B) Schedule I
C) Schedule III
D) Schedule V
Answer
Answer: B
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,Rationale
Schedule I drugs (e.g., heroin, LSD) have high abuse potential and no current medical use.
Question 5
A client asks why a prescription drug costs more than an over-the-counter version. What is the
best response?
A) “Prescription drugs are always stronger.”
B) “Prescription drugs require a provider’s order and may be newer or have specific dosing.”
C) “OTC drugs are safer.”
D) “The government sets the prices.”
Answer
Answer: B
Rationale
Prescription status reflects need for professional oversight, not necessarily strength or safety.
Question 6
Which organ is primarily responsible for drug metabolism?
A) Kidneys
B) Liver
C) Lungs
D) Stomach
Answer
Answer: B
Rationale
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, The liver contains cytochrome P450 enzymes that metabolize most drugs.
Question 7
A nurse is administering a medication to a 2-year-old child. Which factor most affects dosing?
A) The child’s weight
B) Body surface area and weight
C) Age alone
D) The child’s height
Answer
Answer: B
Rationale
Pediatric doses are most accurately calculated using weight or body surface area, not age alone.
Question 8
Which of the following is a high-alert medication?
A) Acetaminophen
B) Heparin
C) Multivitamin
D) Loratadine
Answer
Answer: B
Rationale
High-alert medications (e.g., heparin, insulin, opioids) have a high risk of harm if used incorrectly.
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