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Question 1
A patient is prescribed amoxicillin for strep throat. Which instruction is most important?
A) Take the medication with food
B) Complete the full course even if symptoms improve
C) Stop taking if a rash develops
D) Take at bedtime only
Answer
Answer: B
Rationale
Completing the full antibiotic course prevents resistance and relapse. Rash may indicate allergy, but full
course is key for strep.
Question 2
Which antibiotic class is associated with tendinitis and tendon rupture?
A) Penicillins
B) Fluoroquinolones
C) Macrolides
D) Cephalosporins
Answer
Answer: B
,Rationale
Fluoroquinolones (ciprofloxacin, levofloxacin) increase risk of tendonitis and tendon rupture, especially
Achilles tendon.
Question 3
A patient on vancomycin develops flushing of the face and neck during infusion. This is known
as:
A) Anaphylaxis
B) Red man syndrome
C) Stevens-Johnson syndrome
D) Serum sickness
Answer
Answer: B
Rationale
Red man syndrome is a histamine-mediated reaction from rapid vancomycin infusion; slow the rate
and premedicate with antihistamines.
Question 4
Which antibiotic requires monitoring of serum levels to prevent ototoxicity and nephrotoxicity?
A) Amoxicillin
B) Gentamicin
C) Azithromycin
D) Doxycycline
Answer
Answer: B
Rationale
2
,Aminoglycosides (gentamicin, tobramycin) are nephrotoxic and ototoxic; monitor peak and trough
levels.
Question 5
A patient is prescribed metronidazole. Which instruction is essential?
A) Take with dairy products
B) Avoid alcohol during and for 3 days after therapy
C) Take on an empty stomach
D) Avoid sunlight
Answer
Answer: B
Rationale
Metronidazole with alcohol causes a disulfiram-like reaction (flushing, nausea, vomiting, headache).
Question 6
Which antibiotic is contraindicated in children under 8 years due to tooth discoloration?
A) Amoxicillin
B) Tetracycline
C) Azithromycin
D) Cephalexin
Answer
Answer: B
Rationale
Tetracyclines bind to developing teeth and bones, causing permanent discoloration; avoid in children
<8 and pregnancy.
3
, Question 7
A patient on isoniazid (INH) for TB should receive which vitamin supplement?
A) Vitamin B12
B) Vitamin B6 (pyridoxine)
C) Vitamin C
D) Folic acid
Answer
Answer: B
Rationale
INH interferes with pyridoxine metabolism, causing peripheral neuropathy; supplement with B6.
Question 8
Which antifungal is used for systemic fungal infections and requires monitoring of liver
function?
A) Nystatin
B) Ketoconazole
C) Clotrimazole
D) Miconazole
Answer
Answer: B
Rationale
Oral ketoconazole is hepatotoxic; monitor LFTs. Topical azoles have minimal systemic absorption.
Question 9
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