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ACTUAL EXAM TEST BANK 100
QUESTIONS AND CORRECT
DETAILED ANSWERS WITH
RATIONALES|AGRADE
The mechanism of radioactive iodine in the treatment of Grave's disease is to:
A. Destroy the overactive thyroid tissue
B. Reduce the production of TSH
C. Alter thyroid metabolic rate
D. Relieve distress caused by increased thyroid size
A. Destroy the overactive thyroid tissue
--By decreasing viability of a portion of the thyroid gland the aim is to have normal levels of
thyroid hormone produced.
When norepinephrine binds with alpha-2 receptors, the expected physiologic response is
which one of the following?
A. Bradycardia
B. Tachycardia
C. Bladder relaxation
D. Hypertension
A. Bradycardia
--
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A patient receiving the loop diuretic furosemide may experience which "first dose" adverse
reaction?
A. Hypokalemia
B. Ototoxicity
C. Nephrotoxicity
D. Hypotension
D. Hypotension
--The loop diuretic category is the fastest acting diuretic therefore the first dose adverse
effect most common would be hypotension. Hypokalemia may also be the case if the
patient had borderline low potassium before receiving the medication but that information
is not evident. Ototoxicity and nephrotoxicity are more common with repeated doses of this
medication category.
A 30-week pregnant female should not receive which vaccine?
A. Tdap
B. Influenza
C. Hepatitis B
D. varicella
D. varicella
--The effects of the varicella vaccine are unknown therefore this vaccine is contraindicated.
Congenital defects are a possible consequence to the fetus when live vaccines are
administered during pregnancy, particularly the first 2 trimesters. Non-pregnant females
should not become pregnant for at least 1 month after receiving the vaccine.
The cornerstone of pharmacotherapy in treating Alzheimer's disease is:
A. Cholinesterase inhibitors
B. NMDA receptor antagonists
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C. Psychotropic medications
D. Anxiolytics
A. Cholinesterase inhibitors
What is the gold standard for the suspected diagnosis of Celiac Disease?
Endoscopy with small intestine biopsy
A 44-year-old woman has recently been diagnosed with advanced metastatic non-small-cell
lung cancer. Genetic testing is ordered to determine if the patient's tumor has any genomic
alterations and to guide treatment decisions. A few weeks later, the patient's test results
come back positive for a genetic mutation. The APN starts osimertinib (Tagrisso). Based on
this information, what type of genetic mutation does this patient have?
EGFR mutation
A 20-year-old male meets with an advanced professional nurse (APN) to discuss symptoms
that have been slowly progressing over the past several years. He is mainly concerned
because he has been falling frequently. Since childhood, his gait has consisted of walking on
his toes. During middle school, he was able to participate in sports but was unable to
participate in high school sports due to difficulty with running and jumping. Lately, he has
noticed it takes longer and is more difficult to change positions from sitting to standing than
it used to in the past. He has also been waking up with muscle and joint stiffness. The APRN
notes that his family history is not significant for any chronic or genetic diseases. Which
condition is likely to be the cause of these symptoms?
Becker muscular dystrophy
--Becker muscular dystrophy (often called Becker MD or BMD) is a form of muscular
dystrophy, a genetic disorder that gradually makes the body's muscles weaker and smaller.
It causes less severe problems than the most common type, Duchenne muscular dystrophy.
Which statement should the provider give the patient regarding the pathophysiology of SLE
and its relation to thrombocytopenia?
SLE disrupts immune homeostasis and promotes development of self-reactive antibodies.
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WGU D027 OA EXAM 2025/ 2026
ACTUAL EXAM TEST BANK 100
QUESTIONS AND CORRECT
DETAILED ANSWERS WITH
RATIONALES|AGRADE
The mechanism of radioactive iodine in the treatment of Grave's disease is to:
A. Destroy the overactive thyroid tissue
B. Reduce the production of TSH
C. Alter thyroid metabolic rate
D. Relieve distress caused by increased thyroid size
A. Destroy the overactive thyroid tissue
--By decreasing viability of a portion of the thyroid gland the aim is to have normal levels of
thyroid hormone produced.
When norepinephrine binds with alpha-2 receptors, the expected physiologic response is
which one of the following?
A. Bradycardia
B. Tachycardia
C. Bladder relaxation
D. Hypertension
A. Bradycardia
--
A)*)()(*)(WGU
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2 of 28OA EXAM
A patient receiving the loop diuretic furosemide may experience which "first dose" adverse
reaction?
A. Hypokalemia
B. Ototoxicity
C. Nephrotoxicity
D. Hypotension
D. Hypotension
--The loop diuretic category is the fastest acting diuretic therefore the first dose adverse
effect most common would be hypotension. Hypokalemia may also be the case if the
patient had borderline low potassium before receiving the medication but that information
is not evident. Ototoxicity and nephrotoxicity are more common with repeated doses of this
medication category.
A 30-week pregnant female should not receive which vaccine?
A. Tdap
B. Influenza
C. Hepatitis B
D. varicella
D. varicella
--The effects of the varicella vaccine are unknown therefore this vaccine is contraindicated.
Congenital defects are a possible consequence to the fetus when live vaccines are
administered during pregnancy, particularly the first 2 trimesters. Non-pregnant females
should not become pregnant for at least 1 month after receiving the vaccine.
The cornerstone of pharmacotherapy in treating Alzheimer's disease is:
A. Cholinesterase inhibitors
B. NMDA receptor antagonists
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C. Psychotropic medications
D. Anxiolytics
A. Cholinesterase inhibitors
What is the gold standard for the suspected diagnosis of Celiac Disease?
Endoscopy with small intestine biopsy
A 44-year-old woman has recently been diagnosed with advanced metastatic non-small-cell
lung cancer. Genetic testing is ordered to determine if the patient's tumor has any genomic
alterations and to guide treatment decisions. A few weeks later, the patient's test results
come back positive for a genetic mutation. The APN starts osimertinib (Tagrisso). Based on
this information, what type of genetic mutation does this patient have?
EGFR mutation
A 20-year-old male meets with an advanced professional nurse (APN) to discuss symptoms
that have been slowly progressing over the past several years. He is mainly concerned
because he has been falling frequently. Since childhood, his gait has consisted of walking on
his toes. During middle school, he was able to participate in sports but was unable to
participate in high school sports due to difficulty with running and jumping. Lately, he has
noticed it takes longer and is more difficult to change positions from sitting to standing than
it used to in the past. He has also been waking up with muscle and joint stiffness. The APRN
notes that his family history is not significant for any chronic or genetic diseases. Which
condition is likely to be the cause of these symptoms?
Becker muscular dystrophy
--Becker muscular dystrophy (often called Becker MD or BMD) is a form of muscular
dystrophy, a genetic disorder that gradually makes the body's muscles weaker and smaller.
It causes less severe problems than the most common type, Duchenne muscular dystrophy.
Which statement should the provider give the patient regarding the pathophysiology of SLE
and its relation to thrombocytopenia?
SLE disrupts immune homeostasis and promotes development of self-reactive antibodies.
A)*)()(*)(WGU
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