NURS 5334 ADVANCED
PHARMACOLOGY TEST 2 REVIEW
QUESTION SET WITH ACCURATE
ANSWERS
◉ maximal efficacy
Answer: the largest effect that a drug can produce (height of the
curve)
match the intensity of response w/ patient's need
very high max efficacy is not always more desirable
◉ relative potency
Answer: the amount of drug we must give to elicit an effect
rarely an important characteristic of the drug
can be important if lack of potency forces inconveniently large
doses
implies nothing about max efficacy; refers to dose needed to
produce effects
, ◉ receptor
Answer: any functional macromolecule in a cell to which drug
binds to produce its effects (generally proteins)
receptors include enzymes, ribosomes, & tubulin
◉ receptor binding
Answer: Binding of a drug to its receptor is usually reversible
◉ Receptor activity is regulated by ___ ___.
Answer: endogenous compounds
◉ endogenous compund
Answer: compound naturally produced by the body which binds
to and activates that receptor
EX: serotonin, dopamine
◉ When a drug binds to a receptor, it will either ___ or ___ the
body's own regulatory molecules.
Answer: BLOCK or MIMIC
receptor binding increases or decreases the rate of physiologic
activity normally controlled by that receptor
PHARMACOLOGY TEST 2 REVIEW
QUESTION SET WITH ACCURATE
ANSWERS
◉ maximal efficacy
Answer: the largest effect that a drug can produce (height of the
curve)
match the intensity of response w/ patient's need
very high max efficacy is not always more desirable
◉ relative potency
Answer: the amount of drug we must give to elicit an effect
rarely an important characteristic of the drug
can be important if lack of potency forces inconveniently large
doses
implies nothing about max efficacy; refers to dose needed to
produce effects
, ◉ receptor
Answer: any functional macromolecule in a cell to which drug
binds to produce its effects (generally proteins)
receptors include enzymes, ribosomes, & tubulin
◉ receptor binding
Answer: Binding of a drug to its receptor is usually reversible
◉ Receptor activity is regulated by ___ ___.
Answer: endogenous compounds
◉ endogenous compund
Answer: compound naturally produced by the body which binds
to and activates that receptor
EX: serotonin, dopamine
◉ When a drug binds to a receptor, it will either ___ or ___ the
body's own regulatory molecules.
Answer: BLOCK or MIMIC
receptor binding increases or decreases the rate of physiologic
activity normally controlled by that receptor
