1
NR 293 PHARMACOLOGY – EXAM 1 QUESTIONS
AND ANSWERS | UPDATED | PASS GUARANTEED |
CHAMBERLAIN UNIVERSITY | Q&As WITH
RATIONALES
COMPETENCY DOMAINS
• Pharmacokinetics and Pharmacodynamics
• Medication Administration Safety and the Rights of Medication Administration
• Drug Nomenclature, Classification, and Prototypes
• Drug Therapy Across the Lifespan (Pediatric, Geriatric, Pregnancy)
• Antimicrobial Pharmacology (Antibiotics, Antifungals, Antivirals)
• Cardiovascular Pharmacology
• Endocrine Pharmacology
• Dosage Calculations and High-Alert Medications
• Professional, Legal, and Ethical Considerations in Pharmacology
INTRODUCTION
This comprehensive examination is designed to assess the knowledge, skills, and competency of
candidates preparing for the NR 293 Pharmacology Exam 1 at Chamberlain University. The
assessment evaluates essential competencies across core domains through multiple-choice and
scenario-based questions. Candidates must demonstrate critical thinking, analytical skills, and
decision-making abilities required to apply pharmacological knowledge effectively in
,2
professional nursing practice. Questions progress from foundational principles to advanced
clinical application, with calculation items integrated throughout.
A nurse is reviewing the concept of pharmacokinetics with a nursing student. Which statement
by the student indicates correct understanding?
A. “Pharmacokinetics is the study of what the drug does to the body.”
B. “Pharmacokinetics is the study of what the body does to the drug.”
C. “Pharmacokinetics is the study of a drug’s mechanism of action.”
D. “Pharmacokinetics is the study of a drug’s adverse effects.”
☑ Correct Answer: B
☑ Explanation: Pharmacokinetics describes how the body handles a drug—absorption,
distribution, metabolism, and excretion. Pharmacodynamics describes what the drug does to
the body, including mechanism of action and adverse effects .
A nurse is preparing to administer an oral medication. The nurse understands that the first-pass
effect primarily occurs in which organ?
A. The kidneys
,3
B. The liver
C. The lungs
D. The heart
☑ Correct Answer: B
☑ Explanation: The first-pass effect is the metabolism of a drug in the liver before it reaches
systemic circulation. Orally absorbed drugs travel via the portal vein to the liver, where a portion
is metabolized and inactivated .
A client asks why a medication is given sublingually rather than orally. The nurse’s best
response is that sublingual administration:
A. avoids first-pass metabolism.
B. requires a larger dose.
C. causes more gastrointestinal upset.
D. is less expensive.
☑ Correct Answer: A
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☑ Explanation: Sublingual drugs dissolve under the tongue and are absorbed directly into the
systemic circulation, bypassing the liver and the first-pass effect .
A drug has a half-life of 6 hours. Approximately how long will it take for the drug to be almost
completely eliminated from the body?
A. 6 hours
B. 12 hours
C. 24–30 hours
D. 48 hours
☑ Correct Answer: C
☑ Explanation: Most drugs are considered effectively removed after approximately 4–5 half-
lives. For a half-life of 6 hours, 4–5 half-lives equals 24–30 hours .
A client with malnutrition and low serum albumin is at increased risk for toxicity from drugs
that are:
A. highly protein-bound.
NR 293 PHARMACOLOGY – EXAM 1 QUESTIONS
AND ANSWERS | UPDATED | PASS GUARANTEED |
CHAMBERLAIN UNIVERSITY | Q&As WITH
RATIONALES
COMPETENCY DOMAINS
• Pharmacokinetics and Pharmacodynamics
• Medication Administration Safety and the Rights of Medication Administration
• Drug Nomenclature, Classification, and Prototypes
• Drug Therapy Across the Lifespan (Pediatric, Geriatric, Pregnancy)
• Antimicrobial Pharmacology (Antibiotics, Antifungals, Antivirals)
• Cardiovascular Pharmacology
• Endocrine Pharmacology
• Dosage Calculations and High-Alert Medications
• Professional, Legal, and Ethical Considerations in Pharmacology
INTRODUCTION
This comprehensive examination is designed to assess the knowledge, skills, and competency of
candidates preparing for the NR 293 Pharmacology Exam 1 at Chamberlain University. The
assessment evaluates essential competencies across core domains through multiple-choice and
scenario-based questions. Candidates must demonstrate critical thinking, analytical skills, and
decision-making abilities required to apply pharmacological knowledge effectively in
,2
professional nursing practice. Questions progress from foundational principles to advanced
clinical application, with calculation items integrated throughout.
A nurse is reviewing the concept of pharmacokinetics with a nursing student. Which statement
by the student indicates correct understanding?
A. “Pharmacokinetics is the study of what the drug does to the body.”
B. “Pharmacokinetics is the study of what the body does to the drug.”
C. “Pharmacokinetics is the study of a drug’s mechanism of action.”
D. “Pharmacokinetics is the study of a drug’s adverse effects.”
☑ Correct Answer: B
☑ Explanation: Pharmacokinetics describes how the body handles a drug—absorption,
distribution, metabolism, and excretion. Pharmacodynamics describes what the drug does to
the body, including mechanism of action and adverse effects .
A nurse is preparing to administer an oral medication. The nurse understands that the first-pass
effect primarily occurs in which organ?
A. The kidneys
,3
B. The liver
C. The lungs
D. The heart
☑ Correct Answer: B
☑ Explanation: The first-pass effect is the metabolism of a drug in the liver before it reaches
systemic circulation. Orally absorbed drugs travel via the portal vein to the liver, where a portion
is metabolized and inactivated .
A client asks why a medication is given sublingually rather than orally. The nurse’s best
response is that sublingual administration:
A. avoids first-pass metabolism.
B. requires a larger dose.
C. causes more gastrointestinal upset.
D. is less expensive.
☑ Correct Answer: A
, 4
☑ Explanation: Sublingual drugs dissolve under the tongue and are absorbed directly into the
systemic circulation, bypassing the liver and the first-pass effect .
A drug has a half-life of 6 hours. Approximately how long will it take for the drug to be almost
completely eliminated from the body?
A. 6 hours
B. 12 hours
C. 24–30 hours
D. 48 hours
☑ Correct Answer: C
☑ Explanation: Most drugs are considered effectively removed after approximately 4–5 half-
lives. For a half-life of 6 hours, 4–5 half-lives equals 24–30 hours .
A client with malnutrition and low serum albumin is at increased risk for toxicity from drugs
that are:
A. highly protein-bound.