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ATI RN Comprehensive Predictor 2025 – Original NCLEX-RN Readiness Practice Exam | 180 Questions with Answers and Rationales

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This document contains 180 original multiple-choice nursing practice questions with answers and rationales designed to support ATI RN Comprehensive Predictor preparation and NCLEX-RN readiness review. Topics cover key nursing concepts across NCLEX-RN client-needs categories, including management of care, safety and infection control, health promotion, psychosocial integrity, basic care and comfort, pharmacological and parenteral therapies, reduction of risk potential, and physiological adaptation. This independent study resource is broadly organized around the NCSBN 2023 NCLEX-RN Test Plan, which was in effect during 2025, along with standard nursing safety and clinical practice concepts. The questions are original and are not copied from ATI, a proprietary predictor, or any live or licensure examination. This document is not ATI-endorsed, professor-verified, or a guarantee of a grade or passing result, and it does not claim to represent ATI’s proprietary predictor blueprint. For educational use only; follow current evidence, prescribing information, facility policies, and instructor guidance, and independently verify medication calculations and clinical interventions in practice.

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ATI RN COMPREHENSIVE PREDICTOR
2025 | Original NCLEX-RN Readiness Practice Exam

180 Multiple-Choice Questions with Answers and Rationales


Independent practice material — not an actual ATI or NCLEX exam.

These questions are original and are not copied from ATI, a proprietary predictor, or any
live/licensure examination. This document is not ATI-endorsed, professor-verified, or a
guarantee of a grade or passing result. It is a study resource broadly organized around
NCLEX-RN client-needs categories; ATI’s proprietary predictor blueprint is not represented.

Educational use only. This exam is not patient-specific clinical advice. Follow current evidence,
prescribing information, facility policy, and instructor guidance; medication calculations and
interventions should be independently verified in practice.

Reference framework: NCSBN 2023 NCLEX-RN Test Plan, which was in effect during 2025,
plus current standard nursing safety and clinical practice concepts.




Page 1 of 66

,Table of Contents
Section 1: Management of Care & Professional Practice (Questions 1–25) ...................................... 3

Section 2: Safety & Infection Control (Questions 26–45) ...................................... 12

Section 3: Health Promotion & Maintenance (Questions 46–65) ...................................... 19

Section 4: Psychosocial Integrity (Questions 66–85) ...................................... 26

Section 5: Basic Care & Comfort (Questions 86–105) ...................................... 33

Section 6: Pharmacological & Parenteral Therapies (Questions 106–130) ...................................... 40

Section 7: Reduction of Risk Potential (Questions 131–155) ...................................... 49

Section 8: Physiological Adaptation & Clinical Judgment (Questions 156–180)
...................................... 58




Page 2 of 66

,Section 1: Management of Care & Professional Practice (Questions
1–25)
Q1: Which nursing action is recommended for airway-first prioritization?
A. Delegate the initial assessment to assistive personnel
B. Ask the client to complete a pain scale first
C. Offer oral fluids to soothe the throat
D. Stay with the client, call for emergency assistance, and support the airway and oxygenation
[CORRECT]
Correct Answer: D
Rationale: Airway obstruction is an immediate threat; emergency support and
airway/oxygenation measures take priority over routine assessment. The other options are
unsafe, less appropriate, or fail to address the priority.
Q2: Which principle should guide the RN’s care for airway-first prioritization?
A. Offer oral fluids to soothe the throat
B. Delegate the initial assessment to assistive personnel
C. Stay with the client, call for emergency assistance, and support the airway and oxygenation
[CORRECT]
D. Leave to obtain the chart before calling for help
Correct Answer: C
Rationale: Airway obstruction is an immediate threat; emergency support and
airway/oxygenation measures take priority over routine assessment. The other options are
unsafe, less appropriate, or fail to address the priority.
Q3: For a client with airway-first prioritization, the nurse reviews this situation: a client
admitted with pneumonia suddenly develops stridor and cannot speak in full sentences.
Which established nursing principle applies?
A. Stay with the client, call for emergency assistance, and support the airway and oxygenation
[CORRECT]
B. Leave to obtain the chart before calling for help
C. Ask the client to complete a pain scale first
D. Offer oral fluids to soothe the throat
Correct Answer: A
Rationale: Airway obstruction is an immediate threat; emergency support and
airway/oxygenation measures take priority over routine assessment. The other options are
unsafe, less appropriate, or fail to address the priority.




Page 3 of 66

, Q4: A nurse receives report that a client admitted with pneumonia suddenly develops
stridor and cannot speak in full sentences. Which action should the nurse take first?
A. Stay with the client, call for emergency assistance, and support the airway and oxygenation
[CORRECT]
B. Leave to obtain the chart before calling for help
C. Delegate the initial assessment to assistive personnel
D. Ask the client to complete a pain scale first
Correct Answer: A
Rationale: Airway obstruction is an immediate threat; emergency support and
airway/oxygenation measures take priority over routine assessment. The other options are
unsafe, less appropriate, or fail to address the priority.
Q5: The nurse is notified that a client admitted with pneumonia suddenly develops stridor
and cannot speak in full sentences. Which intervention addresses the greatest immediate
risk?
A. Delegate the initial assessment to assistive personnel
B. Offer oral fluids to soothe the throat
C. Stay with the client, call for emergency assistance, and support the airway and oxygenation
[CORRECT]
D. Ask the client to complete a pain scale first
Correct Answer: C
Rationale: Airway obstruction is an immediate threat; emergency support and
airway/oxygenation measures take priority over routine assessment. The other options are
unsafe, less appropriate, or fail to address the priority.
Q6: Which nursing action is recommended for delegation to assistive personnel?
A. Delegate the predictable hygiene care, then confirm completion and reassess as needed
[CORRECT]
B. Delegate evaluation of a new change in mental status
C. Ask assistive personnel to teach incentive spirometry
D. Assign medication administration outside the worker’s authorized role
Correct Answer: A
Rationale: Routine, predictable hygiene may be delegated to trained assistive personnel;
assessment, teaching, evaluation, and clinical judgment remain the RN’s responsibility. The
other options are unsafe, less appropriate, or fail to address the priority.




Page 4 of 66

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