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Exam (elaborations)

Microbiology Case Studies: Clinical Scenarios & Practice Questions

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Microbiology Case Studies: Clinical Scenarios & Practice Questions

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Case Studies Microbiology.pdfPage
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TSS Staphylococcus aureus A previously healthy young woman was admitted to the intensive care unit with high
fever, hypotension, nausea, vomiting, disseminated sunburn-like rash, generalized
muscle aches and imminent cardiac and renal failure. Her last menstrual period was
about 5 days ago. A blood sample reveals gram-positive cocci arranged in clusters
that produce beta-hemolytic catalase-positive colonies on sheep blood agar.


Strep throat Streptococcus pyogenes A 10-year-old girl presents to her primary care physician with a severe sore throat,
headache, nausea, and abdominal pain. Examination shows the back of her throat is
covered with white pus-filled nodules. Culture of the exudate on blood agar
produces beta-hemolytic colonies composed of gram-positive cocci in chains.


Neisseria gonorrhea A 15-year-old boy presents at the emergency room with a 24-hour history of painful
urination. He has discharge in his underwear and on the tip of his penis. Urine
appears clear, although many white blood cells are present. The young man gives a
history of heterosexual activity with five partners over the past 6 months. All his
partners were "clean" he said. A Gram stain of the discharge reveals gram-negative
diplococci.




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, Case Studies Microbiology.pdfPage
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Escherichia coli A 20-year-old normally healthy woman with a history of urinary tract infection (UTI)
presents to the emergency room with nausea (no vomiting), left flank pain, fever,
chills, and foul-smelling urine. Urinalysis shows large numbers of white and red
blood cells per high power field accompanied by large numbers of motile, gram-
negative rods.


Escherichia coli (carries exotoxin in this strain) A 9-year-old boy with a 2-day history of diarrhea presents to the emergency room
with blood in his stools and increased stool volume. He has vomited once. The boy
went to a cookout 5 days earlier and ate a hamburger that was still "pink" inside. On
examination he is well, apart from some dehydration. Coliform bacteria exhibiting a
metallic green sheen on EMB agar were identified.


Bubonic plague; Yersinia pestis A male patient returned last weekend from a vacation in Kenya where he went on
safari with his wife. Rodents and fleas were present at the campsite. He presents with
fever, chills, headache, nausea, and weakness. On examination he is found to have
an enlarged lymph node in his groin, which is tender. A sample of blood taken from
the patient shows a capsulated, gram-negative rod present in the bloodstream. The
physician begins treatment of the patient with chloramphenicol immediately.




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