NUR 334
Pharm Exam 2 2026 – Pharmacology Questions,
Answers & Detailed Rationales
📚 WHAT'S INCLUDED
➢ NUR 334 Pharmacology Exam 2 study material
➢ Pharmacology practice questions and answers
➢ Detailed rationales explaining the reasoning behind answers
, NUR 334 Pharm Exam 2 2026 –
Pharmacology Questions, Answers &
Detailed Rationales
1. What drug class does gentamicin belong to?
A. Penicillins
B. Fluoroquinolones
C. Aminoglycosides
D. Macrolides
Correct Answer: C. Aminoglycosides
Rationale: Gentamicin is a prototype drug of the aminoglycoside class,
which also includes streptomycin, amikacin, neomycin, and tobramycin.
Aminoglycosides are bactericidal antibiotics that inhibit protein
synthesis and are used for serious gram-negative infections.
2. What is the indicated use of aminoglycosides? (Select all that apply)
A. Treat severe infections of the abdomen and urinary tract
B. Hospital-acquired pneumonia
C. Bacteremia and endocarditis
,D. Treatment of mild viral infections
E. Serious gram-negative bacterial infections
Correct Answer: A, B, C, E
Rationale: Aminoglycosides are indicated for severe infections of the
abdomen and urinary tract, hospital-acquired pneumonia, bacteremia,
and endocarditis. They are also used for serious gram-negative bacterial
infections and infections caused by staphylococci when penicillins or
other less toxic drugs are contraindicated. They are NOT used for viral
infections.
3. Which antibiotics inhibit protein synthesis? (Select all that apply)
A. Tetracyclines
B. Macrolides
C. Aminoglycosides
D. Penicillins
Correct Answer: A, B, C
Rationale: Tetracyclines, macrolides, and aminoglycosides all work by
inhibiting bacterial protein synthesis. Penicillins work by inhibiting cell
wall synthesis, not protein synthesis.
, 4. Which of the following are pharmacokinetic properties of
gentamicin? (Select all that apply)
A. Well absorbed IM and IV
B. Widely distributed in extracellular fluid
C. Crosses the placenta
D. Good penetration into CSF
E. Greater than 90% renal excretion
Correct Answer: A, B, C, E
Rationale: Gentamicin is well absorbed IM and IV, widely distributed in
extracellular fluid, crosses the placenta, and small amounts enter breast
milk. However, it has POOR penetration into CSF. More than 90% is
excreted renally, with a half-life of 2-4 hours (longer in renal
impairment).
5. What drugs fall into the aminoglycoside drug class? (Select all that
apply)
A. Gentamicin
B. Streptomycin
C. Amikacin
D. Neomycin
E. Tobramycin
Pharm Exam 2 2026 – Pharmacology Questions,
Answers & Detailed Rationales
📚 WHAT'S INCLUDED
➢ NUR 334 Pharmacology Exam 2 study material
➢ Pharmacology practice questions and answers
➢ Detailed rationales explaining the reasoning behind answers
, NUR 334 Pharm Exam 2 2026 –
Pharmacology Questions, Answers &
Detailed Rationales
1. What drug class does gentamicin belong to?
A. Penicillins
B. Fluoroquinolones
C. Aminoglycosides
D. Macrolides
Correct Answer: C. Aminoglycosides
Rationale: Gentamicin is a prototype drug of the aminoglycoside class,
which also includes streptomycin, amikacin, neomycin, and tobramycin.
Aminoglycosides are bactericidal antibiotics that inhibit protein
synthesis and are used for serious gram-negative infections.
2. What is the indicated use of aminoglycosides? (Select all that apply)
A. Treat severe infections of the abdomen and urinary tract
B. Hospital-acquired pneumonia
C. Bacteremia and endocarditis
,D. Treatment of mild viral infections
E. Serious gram-negative bacterial infections
Correct Answer: A, B, C, E
Rationale: Aminoglycosides are indicated for severe infections of the
abdomen and urinary tract, hospital-acquired pneumonia, bacteremia,
and endocarditis. They are also used for serious gram-negative bacterial
infections and infections caused by staphylococci when penicillins or
other less toxic drugs are contraindicated. They are NOT used for viral
infections.
3. Which antibiotics inhibit protein synthesis? (Select all that apply)
A. Tetracyclines
B. Macrolides
C. Aminoglycosides
D. Penicillins
Correct Answer: A, B, C
Rationale: Tetracyclines, macrolides, and aminoglycosides all work by
inhibiting bacterial protein synthesis. Penicillins work by inhibiting cell
wall synthesis, not protein synthesis.
, 4. Which of the following are pharmacokinetic properties of
gentamicin? (Select all that apply)
A. Well absorbed IM and IV
B. Widely distributed in extracellular fluid
C. Crosses the placenta
D. Good penetration into CSF
E. Greater than 90% renal excretion
Correct Answer: A, B, C, E
Rationale: Gentamicin is well absorbed IM and IV, widely distributed in
extracellular fluid, crosses the placenta, and small amounts enter breast
milk. However, it has POOR penetration into CSF. More than 90% is
excreted renally, with a half-life of 2-4 hours (longer in renal
impairment).
5. What drugs fall into the aminoglycoside drug class? (Select all that
apply)
A. Gentamicin
B. Streptomycin
C. Amikacin
D. Neomycin
E. Tobramycin
