Adverse Effects and Drug Interactions-NUR 318 – UPDATED Questions with 100% Verified …
Adverse Effects and Drug Interactions-NUR 318 –
UPDATED Questions with 100% Verified Answers
Section 1: Hypersensitivity, Type, Effects (Q1–Q14)
Question & Answer
Q1 Side Effects
A Can be beneficial or harmful, usually predictable (GLP-1: nausea from the slowing of gastric
emptying)
Q2 Adverse Effects
A Undesired and unexpected, usually more severe. (GLP-1: pancreatitis)
Q3 Primary Actions
A an extension of the drugs primary/intended action
Q4 Secondary Actions
A Effects other than the desired effect. can be either beneficial ot detrimental.
Q5 Hypersensitivity
A When the body creates antibodies against a medication (can range from mild-severe)
Q6 Type 1 Immediate Hypersensitivity
A the release of histamine causing various manifestations such as hives/rash, lip/tounge swelling,
difficulty breathing, dialated pupils, anaphylaxis. usually happens immendiately
Q7 Anaphylaxis
A a life threatening medical emergency that can be treated with epinephrine. requires airway
monitoring and potentially oxygen administration. (secondary treatment is diphenhydramine)
Q8 Type 2 antibody mediated hypersensitivity
A IgG/ IgM attack antigens causing cell death. Seen over a course of a few days. ex: blood
transfusions from a different blood type.
Q9 type 3 immune complex hypersensitivity
A damage to tissues from IgG and IgM circulation in the blood. allergy to protein in certain
medications (usually animal proteins) seen a week or more after exposure to drug.
Q10 Type 4 cell mediated hypersensitivity
A skin manifestations. (itchy rash, hives, peeling skin, blister/ oozing) involves T-cells. occurs
anywhere from hours-days after exposure
Q11 dermatological reactions
A rashes/ hives, Stevens-Johnson syndrome, stomatitis (canker sores)
Page 1 of 6
, Adverse Effects and Drug Interactions-NUR 318 – UPDATED Questions with 100% Verified …
Question & Answer
Q12 Stevens-Johnson Syndrome
A A severe, possibly fatal reaction that mimics a burn; may be due to a medication. starts with flu-like
symptoms then progresses to a painful rash w/ massive blisters
Q13 Gastrointestinal effects
A decrease in mucosal membranes, nausea/vomitting/diarrhea, slow peristalsis
Q14 Superinfections
A infections caused by the destruction of normal flora bacteria by certain drugs, which allow other
bacteria to enter the body and cause infection; may occur during the course of antibiotic therapy
(C. diff)
Section 2: Damage, Interactions, Blood (Q15–Q28)
Question & Answer
Q15 Blood Dyscrasia
A abnormal or pathologic condition of the blood (bone marrow suppression)
Q16 Hepatotoxicity
A liver damage due to medications (jaundice, elevated liver enzymes, fever, malaise, nausea,
abdominal pain)
Q17 Nephrotoxicity
A damage to kidneys from renal vasoconstriction, tubular damage, intratublar obstruction. clinical
manifestations include elevated BUN and creatinine, decreased urine output, fatigue, and
electrolyte imbalances)
Q18 Hypoglycemia
A low blood sugar (insulin lowers BS)
Q19 Hyperglycemia
A high blood sugar (prednisone raises BS)
Q20 Hypokalemia
A Low potassium. Caused by loop diuretics; furosemide. NEVER PUSH POTASSIUM QUICKLY
Q21 Hyperkalemia
A High potassium. caused by Spironolactone; antineoplastic drugs potassium sparing diuretics)
Q22 Ocular damage
A damage to the small blood vessels in eyes (chloroquine)
Q23 Auditory damage
A damage to the 8th cranial nerve (macrolide and aminoglycoside antibiotics)
Page 2 of 6
Adverse Effects and Drug Interactions-NUR 318 –
UPDATED Questions with 100% Verified Answers
Section 1: Hypersensitivity, Type, Effects (Q1–Q14)
Question & Answer
Q1 Side Effects
A Can be beneficial or harmful, usually predictable (GLP-1: nausea from the slowing of gastric
emptying)
Q2 Adverse Effects
A Undesired and unexpected, usually more severe. (GLP-1: pancreatitis)
Q3 Primary Actions
A an extension of the drugs primary/intended action
Q4 Secondary Actions
A Effects other than the desired effect. can be either beneficial ot detrimental.
Q5 Hypersensitivity
A When the body creates antibodies against a medication (can range from mild-severe)
Q6 Type 1 Immediate Hypersensitivity
A the release of histamine causing various manifestations such as hives/rash, lip/tounge swelling,
difficulty breathing, dialated pupils, anaphylaxis. usually happens immendiately
Q7 Anaphylaxis
A a life threatening medical emergency that can be treated with epinephrine. requires airway
monitoring and potentially oxygen administration. (secondary treatment is diphenhydramine)
Q8 Type 2 antibody mediated hypersensitivity
A IgG/ IgM attack antigens causing cell death. Seen over a course of a few days. ex: blood
transfusions from a different blood type.
Q9 type 3 immune complex hypersensitivity
A damage to tissues from IgG and IgM circulation in the blood. allergy to protein in certain
medications (usually animal proteins) seen a week or more after exposure to drug.
Q10 Type 4 cell mediated hypersensitivity
A skin manifestations. (itchy rash, hives, peeling skin, blister/ oozing) involves T-cells. occurs
anywhere from hours-days after exposure
Q11 dermatological reactions
A rashes/ hives, Stevens-Johnson syndrome, stomatitis (canker sores)
Page 1 of 6
, Adverse Effects and Drug Interactions-NUR 318 – UPDATED Questions with 100% Verified …
Question & Answer
Q12 Stevens-Johnson Syndrome
A A severe, possibly fatal reaction that mimics a burn; may be due to a medication. starts with flu-like
symptoms then progresses to a painful rash w/ massive blisters
Q13 Gastrointestinal effects
A decrease in mucosal membranes, nausea/vomitting/diarrhea, slow peristalsis
Q14 Superinfections
A infections caused by the destruction of normal flora bacteria by certain drugs, which allow other
bacteria to enter the body and cause infection; may occur during the course of antibiotic therapy
(C. diff)
Section 2: Damage, Interactions, Blood (Q15–Q28)
Question & Answer
Q15 Blood Dyscrasia
A abnormal or pathologic condition of the blood (bone marrow suppression)
Q16 Hepatotoxicity
A liver damage due to medications (jaundice, elevated liver enzymes, fever, malaise, nausea,
abdominal pain)
Q17 Nephrotoxicity
A damage to kidneys from renal vasoconstriction, tubular damage, intratublar obstruction. clinical
manifestations include elevated BUN and creatinine, decreased urine output, fatigue, and
electrolyte imbalances)
Q18 Hypoglycemia
A low blood sugar (insulin lowers BS)
Q19 Hyperglycemia
A high blood sugar (prednisone raises BS)
Q20 Hypokalemia
A Low potassium. Caused by loop diuretics; furosemide. NEVER PUSH POTASSIUM QUICKLY
Q21 Hyperkalemia
A High potassium. caused by Spironolactone; antineoplastic drugs potassium sparing diuretics)
Q22 Ocular damage
A damage to the small blood vessels in eyes (chloroquine)
Q23 Auditory damage
A damage to the 8th cranial nerve (macrolide and aminoglycoside antibiotics)
Page 2 of 6
