CHEM 210 Module 6 | Biochemistry Exam Q&A | Portage
Learning
These are original practice questions written for study.. They cover common CHEM
210 Module 6 | Biochemistry topics: metabolic integration, fed and fasted states,
hormonal regulation, diabetes mellitus, obesity, vitamins and coenzymes, inborn errors
of metabolism, and clinical applications.
Question 1:
In the fed state, which hormone is primarily elevated?
A. Glucagon
B. Insulin
C. Cortisol
D. Epinephrine
Correct answer: B
Rationale: Insulin is the primary anabolic hormone in the fed state.
Question 2:
Insulin promotes which process in adipose tissue?
A. Lipolysis
B. Lipogenesis
C. Ketogenesis
D. Glycogenolysis
Correct answer: B
Rationale: Insulin stimulates fat storage and inhibits lipolysis.
Question 3:
Insulin promotes glycogen synthesis by activating:
A. Glycogen phosphorylase
B. Glycogen synthase
C. Hormone-sensitive lipase
D. Pyruvate dehydrogenase kinase
Correct answer: B
Rationale: Insulin activates glycogen synthase and inhibits glycogen phosphorylase.
,Question 4:
In the fed state, glucose enters muscle cells primarily via:
A. GLUT1
B. GLUT2
C. GLUT4
D. GLUT5
Correct answer: C
Rationale: Insulin stimulates GLUT4 translocation in muscle and adipose tissue.
Question 5:
Which tissue uses GLUT2 for glucose uptake?
A. Muscle
B. Adipose
C. Liver
D. Brain
Correct answer: C
Rationale: GLUT2 is insulin-independent and found in liver and pancreatic beta cells.
Question 6:
In the fed state, the liver primarily stores glucose as:
A. Glycogen
B. Ketone bodies
C. Free fatty acids
D. Urea
Correct answer: A
Rationale: The liver stores glucose as glycogen via glycogenesis.
Question 7:
In the fed state, excess acetyl-CoA is used for:
A. Fatty acid synthesis
B. Ketogenesis
C. Gluconeogenesis
D. Glycogenolysis
Correct answer: A
Rationale: Excess acetyl-CoA is used for fatty acid synthesis in the fed state.
, Question 8:
Which enzyme is activated by insulin and promotes fatty acid synthesis?
A. Acetyl-CoA carboxylase
B. Hormone-sensitive lipase
C. Glycogen phosphorylase
D. CPT-1
Correct answer: A
Rationale: Insulin activates acetyl-CoA carboxylase.
Question 9:
Insulin inhibits which enzyme in adipose tissue?
A. Lipoprotein lipase
B. Hormone-sensitive lipase
C. Glycogen synthase
D. Acetyl-CoA carboxylase
Correct answer: B
Rationale: Insulin inhibits hormone-sensitive lipase, reducing lipolysis.
Question 10:
In the fed state, protein synthesis is:
A. Increased
B. Decreased
C. Unchanged
D. Stopped
Correct answer: A
Rationale: Insulin promotes protein synthesis and inhibits protein breakdown.
Question 11:
In the fasted state, which hormone is primarily elevated?
A. Insulin
B. Glucagon
C. Leptin
D. Aldosterone
Correct answer: B
Rationale: Glucagon is the primary catabolic hormone in the fasted state.
Learning
These are original practice questions written for study.. They cover common CHEM
210 Module 6 | Biochemistry topics: metabolic integration, fed and fasted states,
hormonal regulation, diabetes mellitus, obesity, vitamins and coenzymes, inborn errors
of metabolism, and clinical applications.
Question 1:
In the fed state, which hormone is primarily elevated?
A. Glucagon
B. Insulin
C. Cortisol
D. Epinephrine
Correct answer: B
Rationale: Insulin is the primary anabolic hormone in the fed state.
Question 2:
Insulin promotes which process in adipose tissue?
A. Lipolysis
B. Lipogenesis
C. Ketogenesis
D. Glycogenolysis
Correct answer: B
Rationale: Insulin stimulates fat storage and inhibits lipolysis.
Question 3:
Insulin promotes glycogen synthesis by activating:
A. Glycogen phosphorylase
B. Glycogen synthase
C. Hormone-sensitive lipase
D. Pyruvate dehydrogenase kinase
Correct answer: B
Rationale: Insulin activates glycogen synthase and inhibits glycogen phosphorylase.
,Question 4:
In the fed state, glucose enters muscle cells primarily via:
A. GLUT1
B. GLUT2
C. GLUT4
D. GLUT5
Correct answer: C
Rationale: Insulin stimulates GLUT4 translocation in muscle and adipose tissue.
Question 5:
Which tissue uses GLUT2 for glucose uptake?
A. Muscle
B. Adipose
C. Liver
D. Brain
Correct answer: C
Rationale: GLUT2 is insulin-independent and found in liver and pancreatic beta cells.
Question 6:
In the fed state, the liver primarily stores glucose as:
A. Glycogen
B. Ketone bodies
C. Free fatty acids
D. Urea
Correct answer: A
Rationale: The liver stores glucose as glycogen via glycogenesis.
Question 7:
In the fed state, excess acetyl-CoA is used for:
A. Fatty acid synthesis
B. Ketogenesis
C. Gluconeogenesis
D. Glycogenolysis
Correct answer: A
Rationale: Excess acetyl-CoA is used for fatty acid synthesis in the fed state.
, Question 8:
Which enzyme is activated by insulin and promotes fatty acid synthesis?
A. Acetyl-CoA carboxylase
B. Hormone-sensitive lipase
C. Glycogen phosphorylase
D. CPT-1
Correct answer: A
Rationale: Insulin activates acetyl-CoA carboxylase.
Question 9:
Insulin inhibits which enzyme in adipose tissue?
A. Lipoprotein lipase
B. Hormone-sensitive lipase
C. Glycogen synthase
D. Acetyl-CoA carboxylase
Correct answer: B
Rationale: Insulin inhibits hormone-sensitive lipase, reducing lipolysis.
Question 10:
In the fed state, protein synthesis is:
A. Increased
B. Decreased
C. Unchanged
D. Stopped
Correct answer: A
Rationale: Insulin promotes protein synthesis and inhibits protein breakdown.
Question 11:
In the fasted state, which hormone is primarily elevated?
A. Insulin
B. Glucagon
C. Leptin
D. Aldosterone
Correct answer: B
Rationale: Glucagon is the primary catabolic hormone in the fasted state.
