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Terms in this set (83)
Most oral drugs are
Receptor families 008
1)Kinase-linked receptors
2)Ligand-gated ion channels
3)G protein-coupled
receptor systems
4)Nuclear receptors
80% What percentage of drugs are taken by mouth
The four processes of Pharmacokinetics
Absorption, distribution,
metabolism, and excretion
The pharmacokinetic phase is composed of four processes
Absorption
Distribution metabolism (or
transformation) and
excretion (or elimination)
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Elimination 007
The action of the kidneys
filtering free unbound drugs,
water soluble drugs, and
drugs that are unchanged
and in which they leave the
body in the urine.
Active absorption Which type of absorption requires a carrier
Disintegration 003
The act or process of
decaying or disintegrating
The nurse supplies knowledge of pharmacokinetics when
Adverse drug effects assessing the patient for possible
Aspirin, or weak acid, is excreted rapidly in ....... Urine
Alkaline
Toxic effects 011
Are likely to occur from
overdosing or drug
accumulation, can be life
threatening.
Why is the bioavailability of the IV route 100%
Because IV doses reach the
systemic circulation
immediately without going
through the G.I. tract
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Terms in this set (83)
Most oral drugs are
Receptor families 008
1)Kinase-linked receptors
2)Ligand-gated ion channels
3)G protein-coupled
receptor systems
4)Nuclear receptors
80% What percentage of drugs are taken by mouth
The four processes of Pharmacokinetics
Absorption, distribution,
metabolism, and excretion
The pharmacokinetic phase is composed of four processes
Absorption
Distribution metabolism (or
transformation) and
excretion (or elimination)
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Elimination 007
The action of the kidneys
filtering free unbound drugs,
water soluble drugs, and
drugs that are unchanged
and in which they leave the
body in the urine.
Active absorption Which type of absorption requires a carrier
Disintegration 003
The act or process of
decaying or disintegrating
The nurse supplies knowledge of pharmacokinetics when
Adverse drug effects assessing the patient for possible
Aspirin, or weak acid, is excreted rapidly in ....... Urine
Alkaline
Toxic effects 011
Are likely to occur from
overdosing or drug
accumulation, can be life
threatening.
Why is the bioavailability of the IV route 100%
Because IV doses reach the
systemic circulation
immediately without going
through the G.I. tract
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