Pharm Exam 2 EXPECTED QUESTIONS WITH VERIFIED
ANSWERS
Question 1.
These medications reduce the perception of pain and create a sense of euphoria
ANSWER
Opioids
- Morphine, codeine, fentanyl, oxycodone
- Bind to opioid receptors
- More potent than nonopioids and used for mod-severe pain
Question 2.
These medications work by reducing inflammation and blocking pain signals
ANSWER
Nonopioids
- NSAIDS
- Acetaminophen
Question 3.
Opioid _______ are substances that block the opioid receptors in your nervous system.
ANSWER
antagonists
Opioid agonists "activate" the body's pain-blocking system
Opioid antagonists "deactivate" and can quickly reverse the effects of an opioid overdose, like:
Slow or stopped breathing
Extreme drowsiness
Unconsciousness
- Narcan
Question 4.
Withdrawal symptoms from opioid use subsides around the ___ day after a patient abruptly stops
ANSWER
5th
,Question 5.
NSAIDs (ibuprofen, naproxen) reduce inflammation and pain by inhibiting ________ enzymes
ANSWER
Cyclooxygenase (COX) enzymes
Question 6.
Acetaminophen (paracetamol) primarily works by affecting _____ and _____ pathways in the brain
ANSWER
Pain; Fever
Question 7.
These medications can be used for mild to mod pain and can be used for various types of pain
including back pain, dental pain, and MSK injury pain
ANSWER
Nonopioids
Question 8.
What type of nonopioid analgesics can cause gastrointestinal pain?
ANSWER
NSAID's
"I SAID my tummy hurts :("
Question 9.
What type of nonopioid analgesics can cause liver damage with overdose?
ANSWER
Acetaminophen
"Minnows live in the sea" (ASEAtaMINophen)(LIVE = liver)
,Question 10.
True or False: Opioids are the first line treatment for many types of pain
ANSWER
i. FALSE
ii. Nonopioids are often the first line of treatment for pain
Question 11.
True or False: Opioids are used for more severe pains as compared to nonopioids
ANSWER
TRUE
Question 12.
What are the 3 types of opioid receptors that opioids work by binding to and activating
ANSWER
Mu, Delta, Kappa
- When opioids bind to these receptors, they block pain signals from reaching the brain and
can also produce feelings of pleasure and euphoria.
Question 13.
What are the natural opioids (opiates)
ANSWER
Morphine, codeine
""Codeine, codeine, codeine coooodieeeeneneee please don't take my natural morpheeeeen"
sung like Jolene by dolly parton
Question 14.
What are the semi-synthetic opioids?
ANSWER
Hydromorphone, Oxycodone, Oxymorphone
"semi trucks horns go HOO HOO"
, Question 15.
What are the synthetic opioids?
ANSWER
Fentanyl, Methadone, Tramadol
"Its a Sin (synthetic) to Follow My Teacher"
Synthetic opioids are used for pain relief and as part of balanced anesthesia.
Question 16.
A chronic disease characterized by compulsive drug seeking and use despite harmful consequences
and is a serious side effect of opioid use
ANSWER
Opioid Use Disorder OUD
Question 17.
is a medication used to treat Opioid Use Disor-
der (OUD), is a long-acting full opioid agonist, and a schedule II-controlled medication
ANSWER
Methadone
- reduces opioid craving and withdrawal and blunts or blocks the effects of opioids. It is a
strong opioid agonist with less severe withdrawal symptoms. Taken daily, it is available in
liquid, powder and diskettes forms.
Methadone is a full opioid agonist.
It doesn't block opioids like an antagonist would.
It prevents other opioids from working effectively by occupying the receptors first and for a
long time.
- methadone takes effect slowly and lasts longer compared to "short acting" opioids
Question 18.
A 35-year-old man presents with restlessness, muscle aches, diarrhea and cravings. He appears
anxious and says he hasn't slept in two nights.
What is this patient most likely experiencing based on his symptoms?
ANSWER
Opioid Withdrawal
ANSWERS
Question 1.
These medications reduce the perception of pain and create a sense of euphoria
ANSWER
Opioids
- Morphine, codeine, fentanyl, oxycodone
- Bind to opioid receptors
- More potent than nonopioids and used for mod-severe pain
Question 2.
These medications work by reducing inflammation and blocking pain signals
ANSWER
Nonopioids
- NSAIDS
- Acetaminophen
Question 3.
Opioid _______ are substances that block the opioid receptors in your nervous system.
ANSWER
antagonists
Opioid agonists "activate" the body's pain-blocking system
Opioid antagonists "deactivate" and can quickly reverse the effects of an opioid overdose, like:
Slow or stopped breathing
Extreme drowsiness
Unconsciousness
- Narcan
Question 4.
Withdrawal symptoms from opioid use subsides around the ___ day after a patient abruptly stops
ANSWER
5th
,Question 5.
NSAIDs (ibuprofen, naproxen) reduce inflammation and pain by inhibiting ________ enzymes
ANSWER
Cyclooxygenase (COX) enzymes
Question 6.
Acetaminophen (paracetamol) primarily works by affecting _____ and _____ pathways in the brain
ANSWER
Pain; Fever
Question 7.
These medications can be used for mild to mod pain and can be used for various types of pain
including back pain, dental pain, and MSK injury pain
ANSWER
Nonopioids
Question 8.
What type of nonopioid analgesics can cause gastrointestinal pain?
ANSWER
NSAID's
"I SAID my tummy hurts :("
Question 9.
What type of nonopioid analgesics can cause liver damage with overdose?
ANSWER
Acetaminophen
"Minnows live in the sea" (ASEAtaMINophen)(LIVE = liver)
,Question 10.
True or False: Opioids are the first line treatment for many types of pain
ANSWER
i. FALSE
ii. Nonopioids are often the first line of treatment for pain
Question 11.
True or False: Opioids are used for more severe pains as compared to nonopioids
ANSWER
TRUE
Question 12.
What are the 3 types of opioid receptors that opioids work by binding to and activating
ANSWER
Mu, Delta, Kappa
- When opioids bind to these receptors, they block pain signals from reaching the brain and
can also produce feelings of pleasure and euphoria.
Question 13.
What are the natural opioids (opiates)
ANSWER
Morphine, codeine
""Codeine, codeine, codeine coooodieeeeneneee please don't take my natural morpheeeeen"
sung like Jolene by dolly parton
Question 14.
What are the semi-synthetic opioids?
ANSWER
Hydromorphone, Oxycodone, Oxymorphone
"semi trucks horns go HOO HOO"
, Question 15.
What are the synthetic opioids?
ANSWER
Fentanyl, Methadone, Tramadol
"Its a Sin (synthetic) to Follow My Teacher"
Synthetic opioids are used for pain relief and as part of balanced anesthesia.
Question 16.
A chronic disease characterized by compulsive drug seeking and use despite harmful consequences
and is a serious side effect of opioid use
ANSWER
Opioid Use Disorder OUD
Question 17.
is a medication used to treat Opioid Use Disor-
der (OUD), is a long-acting full opioid agonist, and a schedule II-controlled medication
ANSWER
Methadone
- reduces opioid craving and withdrawal and blunts or blocks the effects of opioids. It is a
strong opioid agonist with less severe withdrawal symptoms. Taken daily, it is available in
liquid, powder and diskettes forms.
Methadone is a full opioid agonist.
It doesn't block opioids like an antagonist would.
It prevents other opioids from working effectively by occupying the receptors first and for a
long time.
- methadone takes effect slowly and lasts longer compared to "short acting" opioids
Question 18.
A 35-year-old man presents with restlessness, muscle aches, diarrhea and cravings. He appears
anxious and says he hasn't slept in two nights.
What is this patient most likely experiencing based on his symptoms?
ANSWER
Opioid Withdrawal
