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UAMS MLT-MLS Comprehensive Exam Questions Verified and Provided with A+ Graded Answers | Blood Banking, Transfusion Medicine, Immunohematology, Antibody Identification, Hemolytic Reactions, Blood Component Storage, RhIG, Cryoprecipitate & Compatibility Te

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Prepare for the UAMS MLT-MLS Comprehensive Exam with a detailed medical laboratory science review resource focused on blood banking, immunohematology, transfusion medicine, and blood component management. Review clinically significant antibodies associated with delayed hemolytic transfusion reactions, anti-I antibodies, Duffy antibodies, Rh immune globulin (RhIG), direct antiglobulin test (DAT) interpretation, weak D testing, and ABO compatibility testing. Strengthen your understanding of extravascular hemolysis, enzyme-treated antibody panels, positive autocontrols, cold autoantibodies, and polyspecific versus monospecific antiglobulin reagents. Explore transfusion requirements for premature infants, intrauterine transfusions, irradiated blood components, CMV considerations, and the use of cryoprecipitate to replace fibrinogen and fresh frozen plasma (FFP) in selected coagulation disorders. This resource also covers Lewis antibodies, plasma selection for AB recipients, donor deferral concepts, and storage requirements for whole blood, packed red blood cells, leukocyte-reduced RBCs, washed RBCs, irradiated components, frozen and deglycerolized RBCs, random-donor platelets, apheresis platelets, and granulocytes. Designed for medical laboratory technician (MLT) and medical laboratory scientist (MLS) students, this exam-focused material supports concept review, antibody recognition, component selection, and transfusion-service revision. Use the questions and answers to reinforce foundational knowledge and prepare for comprehensive laboratory science assessments. Updated 2026/2027 for convenient digital study and instant access.

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UAMS MLT-MLS Comprehensive
Exam Questions Verified
and Provided with A+
Graded Answers| Latest
Updated 2026

,Which antibody is most associated with delayed hemolytic transfusion reactions?


Anti-Jka


What antibody is associated with Anti-I?


Mycoplasma pneumonia


IgG antibodies cause______hemolysis from sequestration by spleen.


Extravascular




T/F: Enzyme panels will react with Duffy Antibodies (Fya or Fyb).


False


T/F: RhIG at 28 weeks can cause a mom to have a low titer anti-D.


True


What type of blood should be given if from mom to child?


Irradiated

,Room temp crossmatch detects_____errors.


ABO


Why do premature infants typically need transfusions?


Blood loss from lab tests


When phenotyping, use a positive control that is______positive.


Heterozygously


Why is cryoprecipitate normally used?


To replace fibrinogen


What can make an auto control positive? (Distinguish by warming, looking under scope or
saline replacement)


Rouleaux and Cold auto


Cold auto will react with _____ AHG and ___ Monospecific AHG.


Polyspecific; C3

, What kind of plasma can an AB= patient be transfused with?


AB (+ or =)


____transfusion must be fresh, CMV =, radiated and collected with CDPA


Intrauterine


How should intrauterine transfusions be handled?


Radiated and collected with CDPA


When is FFP used?


When PT and PTT are prolonged


At what temperature do Lewis antibodies react?


RT and sometimes 37


What type of hemolysis do Lewis antibodies cause?


In Vitro


How long are sexual partners of IV drug users differed from donating?


1 year


+DAT can make the Rh control ___ when doing weak D test


Positive

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