UAMS - IMMUNOHEMATOLOGY LECTURE 1
EXAM QUESTIONS AND ANSWERS
Intravascular Hemolysis - Correct Answers -Cell membrane is destroyed by
complement (not by antibody)
Extravascular Hemolysis - Correct Answers -Antibody is attached to red cell membrane.
Complex is removed by sleen
Give an example of extravascular hemolysis - Correct Answers --Delayed trasnfusion
reactions
-Fetal Death
Humoral Immunity - Correct Answers -Production of antibodies (Igs) by B lymphs
converted to plasma cells
Antibodies - Correct Answers -Protein synthesized by plasma cell
How is the production of an antibody initialized? - Correct Answers -Following the
interaction of an antigen with a macrophage
Cellular immunity - Correct Answers -Direct interaction of T lymphs with foreign cells
Complement - Correct Answers -Lyses antibody coated red cells and serves to mediate
opsonization to prepare for phagocytosis by neutrophils and macrophages
Antigen - Correct Answers -Substance capable of inducing a specific immune response
Epitope - Correct Answers -Portion of antigen where the antibody combines. "Goodness
of Fit"
Name 2 types of antibodies - Correct Answers -Alloantibody and autoantibody
Alloantibody - Correct Answers -Antibody to foreign substance
Autoantibody - Correct Answers -Antibody to self
Where are antigens located? - Correct Answers -On the red cells
Where are antibodies located? - Correct Answers -In serum or plasma
What is antigen-antibody reaction dependent upon? - Correct Answers -Structure of the
molecule
EXAM QUESTIONS AND ANSWERS
Intravascular Hemolysis - Correct Answers -Cell membrane is destroyed by
complement (not by antibody)
Extravascular Hemolysis - Correct Answers -Antibody is attached to red cell membrane.
Complex is removed by sleen
Give an example of extravascular hemolysis - Correct Answers --Delayed trasnfusion
reactions
-Fetal Death
Humoral Immunity - Correct Answers -Production of antibodies (Igs) by B lymphs
converted to plasma cells
Antibodies - Correct Answers -Protein synthesized by plasma cell
How is the production of an antibody initialized? - Correct Answers -Following the
interaction of an antigen with a macrophage
Cellular immunity - Correct Answers -Direct interaction of T lymphs with foreign cells
Complement - Correct Answers -Lyses antibody coated red cells and serves to mediate
opsonization to prepare for phagocytosis by neutrophils and macrophages
Antigen - Correct Answers -Substance capable of inducing a specific immune response
Epitope - Correct Answers -Portion of antigen where the antibody combines. "Goodness
of Fit"
Name 2 types of antibodies - Correct Answers -Alloantibody and autoantibody
Alloantibody - Correct Answers -Antibody to foreign substance
Autoantibody - Correct Answers -Antibody to self
Where are antigens located? - Correct Answers -On the red cells
Where are antibodies located? - Correct Answers -In serum or plasma
What is antigen-antibody reaction dependent upon? - Correct Answers -Structure of the
molecule