PHARMACOLOGY FOR THE PRIMARY CARE PROVIDER 6TH
EDITION TEST BANK | COMPLETE QUESTIONS & VERIFIED
ANSWERS | DETAILED RATIONALES | LATEST 2026–2027 EXAM
PREP
,table of contents
unit 1: principles of pharmacology for advanced practice ......................................................................... 4
chapter 1 pharmacokinetics and pharmacodynamics .............................................................................. 4
chapter 2 pharmacogenomics ................................................................................................................ 14
chapter 3 prescribing considerations ..................................................................................................... 18
unit 2: topical medications ........................................................................................................................ 35
chapter 4 integumentary system medications ....................................................................................... 35
chapter 5 eye and ear medications ........................................................................................................ 41
unit 3: pulmonary system medications ..................................................................................................... 44
chapter 6 allergy and respiratory medications ....................................................................................... 44
chapter 7 asthma medications ............................................................................................................... 48
chapter 8 chronic obstructive pulmonary disease medications ............................................................. 53
unit 4: cardiovascular system medications ............................................................................................... 57
chapter 9 antihyperlipidemic medications ............................................................................................. 57
chapter 10 antihypertensive medications .............................................................................................. 61
chapter11 coronary heart disease medications ..................................................................................... 65
chapter 12 heart failure medications ..................................................................................................... 68
chapter 13 antiarrhythmic medications ................................................................................................. 72
unit 5: hematologic system medications................................................................................................... 75
chapter 14 anemia medications ............................................................................................................. 75
chapter15 anticlotting medications ........................................................................................................ 80
chapter 16 oral anticancer medications — practice questions .............................................................. 87
unit 6: gastrointestinal system medications ............................................................................................. 94
chapter 17 gastroesophageal reflux disease, gastritis, and peptic ulcer disease medications .............. 94
chapter 18 constipation and diarrhea and ibs medications ................................................................... 97
chapter19 antiemetic medications ....................................................................................................... 100
unit 7: genitourinary system medications ............................................................................................... 104
chapter 20 male genitourinary medications......................................................................................... 104
chapter 21 urinary incontinence medications and urinary analgesics ................................................. 107
unit 8: reproductive system medications ................................................................................................ 111
chapter 22 contraceptive medications ................................................................................................. 111
chapter 23 hormone replacement therapy for biologic males and females ........................................ 116
unit 9: musculoskeletal system medications .......................................................................................... 122
, chapter 24 antiinflammatory medications ........................................................................................... 122
chapter 25 disease-modifying and immune therapy medications ....................................................... 126
chapter 26 antigout medications .......................................................................................................... 130
chapter 27 osteoporosis medications................................................................................................... 134
chapter 28 muscle relaxant medications .............................................................................................. 138
unit 10: central nervous system medications ......................................................................................... 141
chapter 29 migraine headache medications......................................................................................... 141
chapter 30 attention-deficit/hyperactivity disorder medications ........................................................ 146
chapter 31 antiepileptic medications ................................................................................................... 150
chapter 32 parkinson’s disease medications ........................................................................................ 153
chapter 33 dementia and alzheimer’s disease medications................................................................. 157
chapter 34 opioids for pain management and substance use disorder ............................................... 160
unit 11: mental health and behavior-modifying medications ................................................................ 164
chapter 35 antianxiety and insomnia medications ............................................................................... 164
chapter 36 mood disorder medications................................................................................................ 167
chapter 37 antipsychotic medications .................................................................................................. 171
unit 12: endocrine system medications .................................................................................................. 175
chapter 38 thyroid medications ............................................................................................................ 175
chapter 39 adrenal gland medications ................................................................................................. 179
chapter 40 diabetes mellitus medications ............................................................................................ 184
unit 13: anti-infective medications .......................................................................................................... 188
chapter 41 principles for prescribing anti-infective medications in primary care ................................ 188
chapter 42 penicillins ............................................................................................................................ 191
chapter 43 cephalosporins.................................................................................................................... 194
chapter 44 tetracyclines........................................................................................................................ 197
chapter 45 macrolides .......................................................................................................................... 199
chapter 46 fluoroquinolones ................................................................................................................ 201
chapter 47 sulfonamides ...................................................................................................................... 204
chapter 48 antitubercular medications ................................................................................................ 208
chapter 49 antifungal medications ....................................................................................................... 211
chapter 50 antiretroviral medications .................................................................................................. 214
chapter 51 antiprotozoal medications .................................................................................................. 225
unit 14: health promotion........................................................................................................................ 228
, chapter 52 immunizations and immunomodulation medications and schedules ............................... 228
chapter 53 weight management medications ...................................................................................... 235
chapter 54 smoking cessation medications .......................................................................................... 239
Unit 1: principles of pharmacology for advanced practice
Chapter 1 pharmacokinetics and pharmacodynamics
Multiple choice
1. A primary care np prescribes an oral medication that undergoes extensive first-pass
metabolism in the liver. Which effect should the np expect?
A. Increased bioavailability.
B. Decreased bioavailability.
C. Complete absorption into the systemic circulation.
D. Delayed renal excretion without changes in drug levels.
ACCURATE ANS: b
First-pass metabolism occurs when a drug is metabolized in the intestine and/or liver before
reaching the systemic circulation. Extensive first-pass metabolism reduces the amount of active
drug that reaches the circulation and therefore reduces oral bioavailability.
Dif: cognitive level: applying (application)
Ref: chapter 1
EDITION TEST BANK | COMPLETE QUESTIONS & VERIFIED
ANSWERS | DETAILED RATIONALES | LATEST 2026–2027 EXAM
PREP
,table of contents
unit 1: principles of pharmacology for advanced practice ......................................................................... 4
chapter 1 pharmacokinetics and pharmacodynamics .............................................................................. 4
chapter 2 pharmacogenomics ................................................................................................................ 14
chapter 3 prescribing considerations ..................................................................................................... 18
unit 2: topical medications ........................................................................................................................ 35
chapter 4 integumentary system medications ....................................................................................... 35
chapter 5 eye and ear medications ........................................................................................................ 41
unit 3: pulmonary system medications ..................................................................................................... 44
chapter 6 allergy and respiratory medications ....................................................................................... 44
chapter 7 asthma medications ............................................................................................................... 48
chapter 8 chronic obstructive pulmonary disease medications ............................................................. 53
unit 4: cardiovascular system medications ............................................................................................... 57
chapter 9 antihyperlipidemic medications ............................................................................................. 57
chapter 10 antihypertensive medications .............................................................................................. 61
chapter11 coronary heart disease medications ..................................................................................... 65
chapter 12 heart failure medications ..................................................................................................... 68
chapter 13 antiarrhythmic medications ................................................................................................. 72
unit 5: hematologic system medications................................................................................................... 75
chapter 14 anemia medications ............................................................................................................. 75
chapter15 anticlotting medications ........................................................................................................ 80
chapter 16 oral anticancer medications — practice questions .............................................................. 87
unit 6: gastrointestinal system medications ............................................................................................. 94
chapter 17 gastroesophageal reflux disease, gastritis, and peptic ulcer disease medications .............. 94
chapter 18 constipation and diarrhea and ibs medications ................................................................... 97
chapter19 antiemetic medications ....................................................................................................... 100
unit 7: genitourinary system medications ............................................................................................... 104
chapter 20 male genitourinary medications......................................................................................... 104
chapter 21 urinary incontinence medications and urinary analgesics ................................................. 107
unit 8: reproductive system medications ................................................................................................ 111
chapter 22 contraceptive medications ................................................................................................. 111
chapter 23 hormone replacement therapy for biologic males and females ........................................ 116
unit 9: musculoskeletal system medications .......................................................................................... 122
, chapter 24 antiinflammatory medications ........................................................................................... 122
chapter 25 disease-modifying and immune therapy medications ....................................................... 126
chapter 26 antigout medications .......................................................................................................... 130
chapter 27 osteoporosis medications................................................................................................... 134
chapter 28 muscle relaxant medications .............................................................................................. 138
unit 10: central nervous system medications ......................................................................................... 141
chapter 29 migraine headache medications......................................................................................... 141
chapter 30 attention-deficit/hyperactivity disorder medications ........................................................ 146
chapter 31 antiepileptic medications ................................................................................................... 150
chapter 32 parkinson’s disease medications ........................................................................................ 153
chapter 33 dementia and alzheimer’s disease medications................................................................. 157
chapter 34 opioids for pain management and substance use disorder ............................................... 160
unit 11: mental health and behavior-modifying medications ................................................................ 164
chapter 35 antianxiety and insomnia medications ............................................................................... 164
chapter 36 mood disorder medications................................................................................................ 167
chapter 37 antipsychotic medications .................................................................................................. 171
unit 12: endocrine system medications .................................................................................................. 175
chapter 38 thyroid medications ............................................................................................................ 175
chapter 39 adrenal gland medications ................................................................................................. 179
chapter 40 diabetes mellitus medications ............................................................................................ 184
unit 13: anti-infective medications .......................................................................................................... 188
chapter 41 principles for prescribing anti-infective medications in primary care ................................ 188
chapter 42 penicillins ............................................................................................................................ 191
chapter 43 cephalosporins.................................................................................................................... 194
chapter 44 tetracyclines........................................................................................................................ 197
chapter 45 macrolides .......................................................................................................................... 199
chapter 46 fluoroquinolones ................................................................................................................ 201
chapter 47 sulfonamides ...................................................................................................................... 204
chapter 48 antitubercular medications ................................................................................................ 208
chapter 49 antifungal medications ....................................................................................................... 211
chapter 50 antiretroviral medications .................................................................................................. 214
chapter 51 antiprotozoal medications .................................................................................................. 225
unit 14: health promotion........................................................................................................................ 228
, chapter 52 immunizations and immunomodulation medications and schedules ............................... 228
chapter 53 weight management medications ...................................................................................... 235
chapter 54 smoking cessation medications .......................................................................................... 239
Unit 1: principles of pharmacology for advanced practice
Chapter 1 pharmacokinetics and pharmacodynamics
Multiple choice
1. A primary care np prescribes an oral medication that undergoes extensive first-pass
metabolism in the liver. Which effect should the np expect?
A. Increased bioavailability.
B. Decreased bioavailability.
C. Complete absorption into the systemic circulation.
D. Delayed renal excretion without changes in drug levels.
ACCURATE ANS: b
First-pass metabolism occurs when a drug is metabolized in the intestine and/or liver before
reaching the systemic circulation. Extensive first-pass metabolism reduces the amount of active
drug that reaches the circulation and therefore reduces oral bioavailability.
Dif: cognitive level: applying (application)
Ref: chapter 1
