PHRM 3820 Tobacco Cessation Questions with Correct Answers
(Grade A+)
Question 1: What percent of adults currently smoke?
Answer: 13.7%
Question 2: What is the pH of the mouth?
Answer: 7.0
Question 3: cigarette buccal nicotine absorption
Answer: acidic media -> limited absorption
Question 4: pipe, cigar, spit tobacco, oral products buccal nicotine absorption
Answer: alkaline media -> significant absorption
Question 5: How is nicotine absorbed in the lungs?
Answer: "distilled" from burning tobacco and carried in tar droplets to air sacs rapidly absorbed across
respiratory epithelium due to pH 7.4, large alveolar surface area, and extensive capillary system
Question 6: How much nicotine is absorbed per cigarette?
Answer: 1mg
Question 7: dopamine reward pathway
Answer: nicotine stimulates nicotinic receptors in brain, which trigger dopamine release in the prefrontal
cortex mechanism of addiction
Question 8: dopamine levels of nicotine compared to other drugs of abuse
Answer: immediate increase in dopamine, similar to amphetamine steady decline similar to others
Question 9: systemic effects of nicotine
Answer: primarily stimulatory, but can reduce anxiety HR increase 10-20 bpm BP increase 5-10 mmHg
binds to receptors throughout the body
Question 10: timeline of withdrawal symptoms
Answer: symptoms manifest in first 1-2 days peak within the first week subside in 2-4 weeks
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(Grade A+)
Question 1: What percent of adults currently smoke?
Answer: 13.7%
Question 2: What is the pH of the mouth?
Answer: 7.0
Question 3: cigarette buccal nicotine absorption
Answer: acidic media -> limited absorption
Question 4: pipe, cigar, spit tobacco, oral products buccal nicotine absorption
Answer: alkaline media -> significant absorption
Question 5: How is nicotine absorbed in the lungs?
Answer: "distilled" from burning tobacco and carried in tar droplets to air sacs rapidly absorbed across
respiratory epithelium due to pH 7.4, large alveolar surface area, and extensive capillary system
Question 6: How much nicotine is absorbed per cigarette?
Answer: 1mg
Question 7: dopamine reward pathway
Answer: nicotine stimulates nicotinic receptors in brain, which trigger dopamine release in the prefrontal
cortex mechanism of addiction
Question 8: dopamine levels of nicotine compared to other drugs of abuse
Answer: immediate increase in dopamine, similar to amphetamine steady decline similar to others
Question 9: systemic effects of nicotine
Answer: primarily stimulatory, but can reduce anxiety HR increase 10-20 bpm BP increase 5-10 mmHg
binds to receptors throughout the body
Question 10: timeline of withdrawal symptoms
Answer: symptoms manifest in first 1-2 days peak within the first week subside in 2-4 weeks
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