HESI A2 MIDTERM COMPREHENSIVE
EXAM QUESTIONS & ANSWERS
(VERIFIED ANSWERS) WITH EXPERT
EXPLANATIONS | 2026 – 2027 UPDATE
(PDF)
1. Which of the following cell organelles is responsible for the production of ATP through
cellular respiration?
A. Golgi Apparatus
B. Lysosome
C. Mitochondria
D. Ribosome
Answer: C
Conceptual Explanation: Mitochondria are known as the powerhouse of the cell because
they generate most of the cell’s supply of adenosine triphosphate (ATP).
2. In human anatomy, which plane divides the body into superior and inferior portions?
A. Sagittal plane
B. Frontal plane
C. Transverse plane
,D. Coronal plane
Answer: C
Conceptual Explanation: The transverse plane (or horizontal plane) divides the body into
top (superior) and bottom (inferior) halves.
3. Which type of chemical bond involves the complete transfer of electrons from one atom to
another?
A. Covalent bond
B. Hydrogen bond
C. Metallic bond
D. Ionic bond
Answer: D
Conceptual Explanation: Ionic bonds are formed when one or more electrons are
transferred from one atom to another, resulting in oppositely charged ions.
4. Solve for x: 3x - 7 = 2x + 5.
A. x = 12
B. x = 2
C. x = -2
D. x = 6
, Answer: A
Conceptual Explanation: Subtract 2x from both sides to get x - 7 = 5. Add 7 to both sides
to get x = 12.
5. What is the primary function of the large intestine in the digestive system?
A. Absorption of water and electrolytes
B. Protein digestion
C. Bile production
D. Absorption of most nutrients
Answer: A
Conceptual Explanation: The large intestine primarily absorbs water and electrolytes
from indigestible food matter and transmits the useless waste material from the body.
6. Choose the correct word to complete the sentence: The nurse had to _____ the patient’s
concern about the surgery.
A. Aggravate
B. Assuage
C. Instigate
D. Deter
Answer: B
EXAM QUESTIONS & ANSWERS
(VERIFIED ANSWERS) WITH EXPERT
EXPLANATIONS | 2026 – 2027 UPDATE
(PDF)
1. Which of the following cell organelles is responsible for the production of ATP through
cellular respiration?
A. Golgi Apparatus
B. Lysosome
C. Mitochondria
D. Ribosome
Answer: C
Conceptual Explanation: Mitochondria are known as the powerhouse of the cell because
they generate most of the cell’s supply of adenosine triphosphate (ATP).
2. In human anatomy, which plane divides the body into superior and inferior portions?
A. Sagittal plane
B. Frontal plane
C. Transverse plane
,D. Coronal plane
Answer: C
Conceptual Explanation: The transverse plane (or horizontal plane) divides the body into
top (superior) and bottom (inferior) halves.
3. Which type of chemical bond involves the complete transfer of electrons from one atom to
another?
A. Covalent bond
B. Hydrogen bond
C. Metallic bond
D. Ionic bond
Answer: D
Conceptual Explanation: Ionic bonds are formed when one or more electrons are
transferred from one atom to another, resulting in oppositely charged ions.
4. Solve for x: 3x - 7 = 2x + 5.
A. x = 12
B. x = 2
C. x = -2
D. x = 6
, Answer: A
Conceptual Explanation: Subtract 2x from both sides to get x - 7 = 5. Add 7 to both sides
to get x = 12.
5. What is the primary function of the large intestine in the digestive system?
A. Absorption of water and electrolytes
B. Protein digestion
C. Bile production
D. Absorption of most nutrients
Answer: A
Conceptual Explanation: The large intestine primarily absorbs water and electrolytes
from indigestible food matter and transmits the useless waste material from the body.
6. Choose the correct word to complete the sentence: The nurse had to _____ the patient’s
concern about the surgery.
A. Aggravate
B. Assuage
C. Instigate
D. Deter
Answer: B
