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HESI ADMISSION ASSESSMENT (A2)
ACTUAL EXAM 2026/2027 QUESTIONS
WITH VERIFIED ANSWERS & COMPLETE
RATIONALES
**1. A nurse must administer 0.75 mg of a drug from a vial
labeled 0.5 mg/mL. Using a 1 mL syringe graduated in 0.01 mL
increments, what volume should be drawn up?**
A. 0.75 mL
B. 1.5 mL
C. 0.5 mL
D. 1.0 mL
**Correct answer:** B
**Rationale:** Volume = dose ÷ concentration = 0.75 mg ÷ 0.5
mg/mL = **1.5 mL**. The dose is divided by the concentration
to determine the volume to be drawn up .
---
**2. Which of the following is an example of active transport in
the cell?**
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A. Osmosis of water across the membrane
B. Diffusion of oxygen from high to low concentration
C. Movement of sodium against its concentration gradient
D. Facilitated diffusion of glucose via a carrier protein
**Correct answer:** C
**Rationale:** Active transport requires energy (ATP) to move
molecules against their concentration gradient, as in the
sodium-potassium pump. Osmosis and diffusion are passive
processes. Facilitated diffusion is also passive, requiring no
energy .
---
**3. The organelle responsible for protein synthesis is the:**
A. Ribosome
B. Mitochondrion
C. Golgi apparatus
D. Nucleus
**Correct answer:** A
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**Rationale:** Ribosomes are the sites of translation, where
mRNA is used to synthesize proteins. Mitochondria produce
ATP. The Golgi apparatus modifies and packages proteins. The
nucleus contains DNA and directs transcription .
---
**4. Which of the following is NOT a function of the skeletal
system?**
A. Production of blood cells
B. Protection of internal organs
C. Regulation of body temperature
D. Storage of calcium and phosphorus
**Correct answer:** C
**Rationale:** Regulation of body temperature is a function of
the skin and circulatory system, not the skeletal system.
Hematopoiesis (blood cell production), protection, and mineral
storage are primary skeletal functions .
---
**5. Which chamber of the heart receives deoxygenated blood
from the body?**
HESI ADMISSION ASSESSMENT (A2)
ACTUAL EXAM 2026/2027 QUESTIONS
WITH VERIFIED ANSWERS & COMPLETE
RATIONALES
**1. A nurse must administer 0.75 mg of a drug from a vial
labeled 0.5 mg/mL. Using a 1 mL syringe graduated in 0.01 mL
increments, what volume should be drawn up?**
A. 0.75 mL
B. 1.5 mL
C. 0.5 mL
D. 1.0 mL
**Correct answer:** B
**Rationale:** Volume = dose ÷ concentration = 0.75 mg ÷ 0.5
mg/mL = **1.5 mL**. The dose is divided by the concentration
to determine the volume to be drawn up .
---
**2. Which of the following is an example of active transport in
the cell?**
,2 | Page
A. Osmosis of water across the membrane
B. Diffusion of oxygen from high to low concentration
C. Movement of sodium against its concentration gradient
D. Facilitated diffusion of glucose via a carrier protein
**Correct answer:** C
**Rationale:** Active transport requires energy (ATP) to move
molecules against their concentration gradient, as in the
sodium-potassium pump. Osmosis and diffusion are passive
processes. Facilitated diffusion is also passive, requiring no
energy .
---
**3. The organelle responsible for protein synthesis is the:**
A. Ribosome
B. Mitochondrion
C. Golgi apparatus
D. Nucleus
**Correct answer:** A
, 3 | Page
**Rationale:** Ribosomes are the sites of translation, where
mRNA is used to synthesize proteins. Mitochondria produce
ATP. The Golgi apparatus modifies and packages proteins. The
nucleus contains DNA and directs transcription .
---
**4. Which of the following is NOT a function of the skeletal
system?**
A. Production of blood cells
B. Protection of internal organs
C. Regulation of body temperature
D. Storage of calcium and phosphorus
**Correct answer:** C
**Rationale:** Regulation of body temperature is a function of
the skin and circulatory system, not the skeletal system.
Hematopoiesis (blood cell production), protection, and mineral
storage are primary skeletal functions .
---
**5. Which chamber of the heart receives deoxygenated blood
from the body?**
