CPIA Exam 2027 Questions and Answers | Detailed Review
with Correct Solutions | Grade A+
Question 1.
Which of the following should be considered a significant change to an animal use
proposal?
A. change in departmental affiliation of the principal investigator
B. change in start date of study
C. change in anesthetic agent
D. change in fluid administration
Correct Answer: C. change in anesthetic agent
Question 2.
Which of the following entities are required to release information per the Freedom of
Information Act?
A. OLAW
B. AAALAC
C. IACUC
D. HSUS
Correct Answer: A. OLAW
Question 3.
Training and instruction of personnel must include guidance in which of the following
areas?
A. Effective writing of animal use proposals
B. Proper use of personal protective equipment
C. Appropriate communication with animal activist groups
D. Research or testing methods that limit the use of animals
Correct Answer: D. Research or testing methods that limit the use of animals
Question 4.
Which of the following procedures may correctly be applied to Designated Member
Review?
A. The IACUC Chair appoints one member to do the Designated Member Review.
B. The designated member reviewer is authorized to approve, require modifications, or
disapprove the proposal.
C. All members receive information about the proposal and send their votes to the
designated member reviewer for tallying.
D. Designated member review may be utilized to review proposals when there is
insufficient time to notify the full membership of the proposal details.
Correct Answer: A. The IACUC Chair appoints one member to do the
Designated Member Review.
,Question 5.
In which of the following circumstances may animal work begin before receipt of IACUC
approval?
A. It is a continuing study awaiting three year renewal and for which the renewal
protocol has been submitted to the IACUC.
B. It is a small pilot study on non-AWAR species.
C. It is a teaching activity that uses students' personally owned dogs and cats.
D. There are no circumstances in which animal work may begin before IACUC approval.
Correct Answer: D. There are no circumstances in which animal work may
begin before IACUC approval.
Question 6.
Which of the statements below about the responsibility and authority of the Institutional
Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the animal
care and use program.
B. The IO must be the institution's Chief Executive Officer or some appointed by him
with authority to fund resources.
C. The IO may reinstate an animal activity that was previously suspended by the IACUC.
D. The IO may suspend an animal activity that was previously approved by the IACUC.
Correct Answer: C. The IO may reinstate an animal activity that was previously
suspended by the IACUC.
Question 7.
With regard to conducting official IACUC business, the definition of a quorum is:
A. More than fifty percent (a majority) of voting members.
B. Fifty percent of voting and non-voting members combined.
C. More than fifty percent (a majority) of voting and non-voting members combined.
D. Fifty percent of the voting members.
Correct Answer: A. More than fifty percent (a majority) of voting members
Question 8.
The proper sequence for a designated member review by the IACUC is:
A. Review materials are sent to all voting members, full committee review is not
requested by any member, the chairperson assigns one or more IACUC members as
designated reviewers.
B. Review materials are sent to a quorum of designated reviewers, review results are
solicited from designated reviewers, full committee approval of results is requested.
C. Review materials are sent to all voting members, a majority of members do not
request full committee review, the chairperson assigns one or more IACUC members as
designated reviewers.
D. Review materials are sent to a quorum of voting members, a majority of a quorum
,does not request full committee review, the chairperson assigns one or more IACUC
members as designated reviewers.
Correct Answer: A. Review materials are sent to all voting members, full
committee review is not requested by any member, the chairperson assigns
one or more IACUC members as designated reviewers.
Question 9.
Notifying investigators of IACUC protocol review outcomes in writing is:
A. A common courtesy not required by regulatory authorities.
B. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only after the
minutes have been prepared and approved by the IACUC during a convened meeting.
C. Required by both the USDA Animal Welfare Act Regulations and PHS Policy.
D. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only after the IO
is notified of the review outcome.
Correct Answer: C. Required by both the USDA Animal Welfare Act Regulations
and PHS Policy.
Question 10.
According to the Animal Welfare Act Regulations of the USDA, when conducting a
semi-annual evaluation, the IACUC must conduct the evaluation:
A. With at least 1 IACUC member and allow participation by any member who wishes to
do so.
B. With at least 2 IACUC members and allow participation by any member who wishes to
do so.
C. With a majority of IACUC members present, including the non-affiliated member.
D. With all IACUC members present.
Correct Answer: B. With at least 2 IACUC members and allow participation by
any member who wishes to do so.
Question 11.
Who is given the authority to decide if a deficiency identified during a semi- annual
IACUC evaluation is significant or minor?
A. The IACUC and IO together.
B. The veterinarian and the IACUC together.
C. Only the IACUC.
D. Only the IO.
Correct Answer: A. The IACUC and IO together.
Question 12.
What information must be provided in the report for deficiencies identified during the
IACUC semi-annual self-evaluation?
A. A reasonable and specific plan and schedule for correcting significant deficiencies,
, and a description of minor deficiencies.
B. A reasonable and specific plan for correcting significant and minor deficiencies and a
schedule for completing the corrective actions.
C. The name and title of the IACUC member who will perform the corrections and the
institutional official in charge of verifying the corrections.
D. The name and title of institutional support personnel who will provide the corrections
and the IACUC members in charge of verifying the corrections.
Correct Answer: B. A reasonable and specific plan for correcting significant
and minor deficiencies and a schedule for completing the corrective actions.
Question 13.
Which of the following institutions must follow the PHS Policy?
A. Institutions that use any animals for research, teaching, or testing.
B. Institutions that use vertebrate animals for research, teaching, or testing.
C. Institutions that accept USDA research funds.
D. Institutions that accept PHS funding.
Correct Answer: D. Institutions that accept PHS funding.
Question 14.
The three Rs of Russell and Burch stand for what?
A. Research, refinement, and recovery.
B. Replace, recognize, and recover.
C. Replacement, reduction, and refinement.
D. Research, results, and review.
Correct Answer: C. Replacement, reduction, and refinement.
Question 15.
What is a primary mission of the Animal Welfare Information Center (AWIC)?
A. Publishes the Animal Welfare Act Regulations and Standards.
B. Provides assistance with alternatives and database searches.
C. Publishes the Guide for the Care and Use of Laboratory Animals.
D. Provides assistance with identifying the best laboratory animal cage washing
equipment.
Correct Answer: B. Provides assistance with alternatives and database
searches.
Question 16.
Which agency requires an annual report of the number of animals used by pain/distress
category?
A. American Association for Laboratory Animal Science
B. Association for Assessment and Accreditation of Laboratory Animal Care
C. Office of Laboratory Animal Welfare
with Correct Solutions | Grade A+
Question 1.
Which of the following should be considered a significant change to an animal use
proposal?
A. change in departmental affiliation of the principal investigator
B. change in start date of study
C. change in anesthetic agent
D. change in fluid administration
Correct Answer: C. change in anesthetic agent
Question 2.
Which of the following entities are required to release information per the Freedom of
Information Act?
A. OLAW
B. AAALAC
C. IACUC
D. HSUS
Correct Answer: A. OLAW
Question 3.
Training and instruction of personnel must include guidance in which of the following
areas?
A. Effective writing of animal use proposals
B. Proper use of personal protective equipment
C. Appropriate communication with animal activist groups
D. Research or testing methods that limit the use of animals
Correct Answer: D. Research or testing methods that limit the use of animals
Question 4.
Which of the following procedures may correctly be applied to Designated Member
Review?
A. The IACUC Chair appoints one member to do the Designated Member Review.
B. The designated member reviewer is authorized to approve, require modifications, or
disapprove the proposal.
C. All members receive information about the proposal and send their votes to the
designated member reviewer for tallying.
D. Designated member review may be utilized to review proposals when there is
insufficient time to notify the full membership of the proposal details.
Correct Answer: A. The IACUC Chair appoints one member to do the
Designated Member Review.
,Question 5.
In which of the following circumstances may animal work begin before receipt of IACUC
approval?
A. It is a continuing study awaiting three year renewal and for which the renewal
protocol has been submitted to the IACUC.
B. It is a small pilot study on non-AWAR species.
C. It is a teaching activity that uses students' personally owned dogs and cats.
D. There are no circumstances in which animal work may begin before IACUC approval.
Correct Answer: D. There are no circumstances in which animal work may
begin before IACUC approval.
Question 6.
Which of the statements below about the responsibility and authority of the Institutional
Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the animal
care and use program.
B. The IO must be the institution's Chief Executive Officer or some appointed by him
with authority to fund resources.
C. The IO may reinstate an animal activity that was previously suspended by the IACUC.
D. The IO may suspend an animal activity that was previously approved by the IACUC.
Correct Answer: C. The IO may reinstate an animal activity that was previously
suspended by the IACUC.
Question 7.
With regard to conducting official IACUC business, the definition of a quorum is:
A. More than fifty percent (a majority) of voting members.
B. Fifty percent of voting and non-voting members combined.
C. More than fifty percent (a majority) of voting and non-voting members combined.
D. Fifty percent of the voting members.
Correct Answer: A. More than fifty percent (a majority) of voting members
Question 8.
The proper sequence for a designated member review by the IACUC is:
A. Review materials are sent to all voting members, full committee review is not
requested by any member, the chairperson assigns one or more IACUC members as
designated reviewers.
B. Review materials are sent to a quorum of designated reviewers, review results are
solicited from designated reviewers, full committee approval of results is requested.
C. Review materials are sent to all voting members, a majority of members do not
request full committee review, the chairperson assigns one or more IACUC members as
designated reviewers.
D. Review materials are sent to a quorum of voting members, a majority of a quorum
,does not request full committee review, the chairperson assigns one or more IACUC
members as designated reviewers.
Correct Answer: A. Review materials are sent to all voting members, full
committee review is not requested by any member, the chairperson assigns
one or more IACUC members as designated reviewers.
Question 9.
Notifying investigators of IACUC protocol review outcomes in writing is:
A. A common courtesy not required by regulatory authorities.
B. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only after the
minutes have been prepared and approved by the IACUC during a convened meeting.
C. Required by both the USDA Animal Welfare Act Regulations and PHS Policy.
D. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only after the IO
is notified of the review outcome.
Correct Answer: C. Required by both the USDA Animal Welfare Act Regulations
and PHS Policy.
Question 10.
According to the Animal Welfare Act Regulations of the USDA, when conducting a
semi-annual evaluation, the IACUC must conduct the evaluation:
A. With at least 1 IACUC member and allow participation by any member who wishes to
do so.
B. With at least 2 IACUC members and allow participation by any member who wishes to
do so.
C. With a majority of IACUC members present, including the non-affiliated member.
D. With all IACUC members present.
Correct Answer: B. With at least 2 IACUC members and allow participation by
any member who wishes to do so.
Question 11.
Who is given the authority to decide if a deficiency identified during a semi- annual
IACUC evaluation is significant or minor?
A. The IACUC and IO together.
B. The veterinarian and the IACUC together.
C. Only the IACUC.
D. Only the IO.
Correct Answer: A. The IACUC and IO together.
Question 12.
What information must be provided in the report for deficiencies identified during the
IACUC semi-annual self-evaluation?
A. A reasonable and specific plan and schedule for correcting significant deficiencies,
, and a description of minor deficiencies.
B. A reasonable and specific plan for correcting significant and minor deficiencies and a
schedule for completing the corrective actions.
C. The name and title of the IACUC member who will perform the corrections and the
institutional official in charge of verifying the corrections.
D. The name and title of institutional support personnel who will provide the corrections
and the IACUC members in charge of verifying the corrections.
Correct Answer: B. A reasonable and specific plan for correcting significant
and minor deficiencies and a schedule for completing the corrective actions.
Question 13.
Which of the following institutions must follow the PHS Policy?
A. Institutions that use any animals for research, teaching, or testing.
B. Institutions that use vertebrate animals for research, teaching, or testing.
C. Institutions that accept USDA research funds.
D. Institutions that accept PHS funding.
Correct Answer: D. Institutions that accept PHS funding.
Question 14.
The three Rs of Russell and Burch stand for what?
A. Research, refinement, and recovery.
B. Replace, recognize, and recover.
C. Replacement, reduction, and refinement.
D. Research, results, and review.
Correct Answer: C. Replacement, reduction, and refinement.
Question 15.
What is a primary mission of the Animal Welfare Information Center (AWIC)?
A. Publishes the Animal Welfare Act Regulations and Standards.
B. Provides assistance with alternatives and database searches.
C. Publishes the Guide for the Care and Use of Laboratory Animals.
D. Provides assistance with identifying the best laboratory animal cage washing
equipment.
Correct Answer: B. Provides assistance with alternatives and database
searches.
Question 16.
Which agency requires an annual report of the number of animals used by pain/distress
category?
A. American Association for Laboratory Animal Science
B. Association for Assessment and Accreditation of Laboratory Animal Care
C. Office of Laboratory Animal Welfare
