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1. Which finding is most consistent with uncontrolled asthma?
A. Daytime symptoms once every 3 weeks
B. Nighttime awakening once every 2 months
C. Needing a rescue inhaler several times per week
D. No activity limitation
ANSWER: C. Needing a rescue inhaler several times per week
RATIONALE: Frequent reliever use is a marker of poor asthma control.
Other indicators include frequent daytime symptoms, nighttime
awakening, and activity limitation.
2. Which medication is the preferred inhaled corticosteroid (ICS)
component of long-term asthma control?
A. Albuterol
B. Budesonide
C. Ipratropium
,D. Tiotropium
ANSWER: B. Budesonide
RATIONALE: Budesonide is an inhaled corticosteroid that decreases
airway inflammation and is used for long-term asthma control.
Albuterol is a short-acting bronchodilator, while ipratropium and
tiotropium are anticholinergics.
3. What is the primary therapeutic effect of inhaled corticosteroids in
asthma?
A. Immediate relaxation of bronchial smooth muscle
B. Reduction of airway inflammation
C. Direct stimulation of beta-2 receptors
D. Increased mucus production
ANSWER: B. Reduction of airway inflammation
RATIONALE: ICS therapy suppresses airway inflammation and
hyperresponsiveness. It is a controller treatment rather than an
immediate rescue medication.
,4. Which instruction is most important after using an inhaled
corticosteroid?
A. Drink grapefruit juice
B. Rinse the mouth after administration
C. Take it only during an acute attack
D. Avoid drinking water for 2 hours
ANSWER: B. Rinse the mouth after administration
RATIONALE: Rinsing the mouth decreases the risk of oral candidiasis
and local adverse effects associated with inhaled corticosteroids.
5. Which medication is a short-acting beta-2 agonist (SABA)?
A. Salmeterol
B. Albuterol
C. Tiotropium
D. Montelukast
ANSWER: B. Albuterol
, RATIONALE: Albuterol is a SABA that rapidly relaxes bronchial smooth
muscle. Salmeterol is a LABA; tiotropium is a LAMA; montelukast is a
leukotriene receptor antagonist.
6. Which adverse effect is most associated with beta-2 agonists?
A. Bradycardia
B. Tremor and tachycardia
C. Severe constipation
D. Urinary retention
ANSWER: B. Tremor and tachycardia
RATIONALE: Beta-2 agonists can cause tremor, nervousness,
palpitations, and tachycardia. Hypokalemia can also occur, particularly
with high doses.
7. Which statement about LABAs in asthma is correct?
A. LABAs should routinely be used alone
B. LABAs replace corticosteroids
C. LABAs should be combined with an ICS in asthma
D. LABAs are only used for acute attacks