PANCE -INFECTIOUS DISEASE |ACTUAL
QUESTIONS AND VERIFIED ANSWERS|BRAND NEW
2026-2027 UPDATE|GRADED A+
Question 1
Which of the following is the most definitive method for diagnosing anaplasmosis?
A. Peripheral blood smear
B. Polymerase chain reaction (PCR)
C. Serologic testing for antibodies
D. Blood cultures
E. Bone marrow biopsy
CORRECT ANSWER
B. Polymerase chain reaction (PCR)
Question 2
Which of the following statements regarding anaplasmosis and Lyme disease is true?
A. Both anaplasmosis and Lyme disease are endemic in the southeastern United States
B. Lyme disease is more common in the Rocky Mountain region than anaplasmosis
C. Anaplasmosis is primarily found in the Pacific Northwest, whereas Lyme disease is not
D. Both anaplasmosis and Lyme disease are transmitted by the same tick species
E. Lyme disease has a higher incidence in urban areas compared to anaplasmosis
CORRECT ANSWER
D. Both anaplasmosis and Lyme disease are transmitted by the same tick species
1
, Anaplasma phagocytophilum
Question 3
Anaplasmosis is caused by a ____________ and presents with ____________
A. Bacterium; neurologic symptoms
B. Bacterium; flu-like symptoms
C. Spirochete; neurologic symptoms
D. Spirochete; flu-like symptoms
CORRECT ANSWER
B. Bacterium; flu-like symptoms
Question 4
A 9-year-old boy presents with a low-grade fever and enlarged, tender lymph nodes in his
neck. His mother reports he was recently scratched by their kitten. Which of the following
is the most likely etiological agent responsible for his symptoms?
A. Borrelia burgdorferi
B. Bartonella henselae
C. Rickettsia rickettsii
D. Ehrlichia chaffeensis
E. Anaplasma phagocytophilum
CORRECT ANSWER
B. Bartonella henselae
2
,Question 5
A 45-year-old homeless man presents with recurrent episodes of fever, headache, and
severe bone pain in his shins. He reports poor hygiene and frequent louse infestation.
Which of the following is the most likely etiological agent responsible for his symptoms?
A. Borrelia recurrentis
B. Bartonella quintana
C. Bartonella henselae
D. Bacillary angiomatosis
E. Coxiella burnetii
CORRECT ANSWER
B. Bartonella quintana
The clinical presentation of recurrent fever, headache, and bone pain (especially shin
bone pain), combined with the history of poor hygiene and louse infestation, strongly
suggests trench fever. This disease is specifically caused by the bacterium Bartonella
quintana, which is transmitted through the bite of body lice (Pediculus humanus
corporis). The bacteria multiply within the louse's gut and are excreted in their feces.
When an infected louse bites, scratching the bite site inoculates the bacteria into the
bloodstream. Trench fever is reappearing in the homeless population in the US.
Question 6
12-year-old boy presents with a 3-day history of fever, headache, and a tender, enlarging
lymph node in his left axilla. He reports being scratched by a kitten 10 days ago. Which of
the following is the most appropriate next step in the diagnosis of this patient's condition?
A. Bartonella henselae IgM antibody test
B. Blood culture for Bartonella species
C. Chest X-ray to rule out pulmonary involvement
D. Lymph node biopsy for histopathologic examination
3
, E. PCR testing of lymph node aspirate for Bartonella DNA
CORRECT ANSWER
E. PCR testing of lymph node aspirate for Bartonella DNA
Question 7
A 25-year-old man with a history of HIV/AIDS (CD4 count: 50 cells/µL) presents with
multiple red, vascular skin lesions on his lower extremities. A skin biopsy reveals bacillary
angiomatosis. Which of the following is the most appropriate treatment for this patient's
condition?
A. Azithromycin 500 mg orally on day 1, followed by 250 mg orally daily for 4 days
B. Doxycycline 100 mg orally twice daily for 3-4 months
C. Ciprofloxacin 500 mg orally twice daily for 7 days
D. Rifampin 300 mg orally twice daily for 2 weeks
E. Trimethoprim-sulfamethoxazole 160/800 mg orally twice daily for 6 weeks
CORRECT ANSWER
B. Doxycycline 100 mg orally twice daily for 3-4 months
Question 8
A complication of Bartonella henselae & Bartonella quintana infection; seen in AIDS
patients, CD4 < 100
A. Coccidioidomycosis
B. Cryptococcosis
C. Pneumocystis pneumonia
D. Phlegmasia cerulea dolens
E. Bacillary angiomatosis
4
QUESTIONS AND VERIFIED ANSWERS|BRAND NEW
2026-2027 UPDATE|GRADED A+
Question 1
Which of the following is the most definitive method for diagnosing anaplasmosis?
A. Peripheral blood smear
B. Polymerase chain reaction (PCR)
C. Serologic testing for antibodies
D. Blood cultures
E. Bone marrow biopsy
CORRECT ANSWER
B. Polymerase chain reaction (PCR)
Question 2
Which of the following statements regarding anaplasmosis and Lyme disease is true?
A. Both anaplasmosis and Lyme disease are endemic in the southeastern United States
B. Lyme disease is more common in the Rocky Mountain region than anaplasmosis
C. Anaplasmosis is primarily found in the Pacific Northwest, whereas Lyme disease is not
D. Both anaplasmosis and Lyme disease are transmitted by the same tick species
E. Lyme disease has a higher incidence in urban areas compared to anaplasmosis
CORRECT ANSWER
D. Both anaplasmosis and Lyme disease are transmitted by the same tick species
1
, Anaplasma phagocytophilum
Question 3
Anaplasmosis is caused by a ____________ and presents with ____________
A. Bacterium; neurologic symptoms
B. Bacterium; flu-like symptoms
C. Spirochete; neurologic symptoms
D. Spirochete; flu-like symptoms
CORRECT ANSWER
B. Bacterium; flu-like symptoms
Question 4
A 9-year-old boy presents with a low-grade fever and enlarged, tender lymph nodes in his
neck. His mother reports he was recently scratched by their kitten. Which of the following
is the most likely etiological agent responsible for his symptoms?
A. Borrelia burgdorferi
B. Bartonella henselae
C. Rickettsia rickettsii
D. Ehrlichia chaffeensis
E. Anaplasma phagocytophilum
CORRECT ANSWER
B. Bartonella henselae
2
,Question 5
A 45-year-old homeless man presents with recurrent episodes of fever, headache, and
severe bone pain in his shins. He reports poor hygiene and frequent louse infestation.
Which of the following is the most likely etiological agent responsible for his symptoms?
A. Borrelia recurrentis
B. Bartonella quintana
C. Bartonella henselae
D. Bacillary angiomatosis
E. Coxiella burnetii
CORRECT ANSWER
B. Bartonella quintana
The clinical presentation of recurrent fever, headache, and bone pain (especially shin
bone pain), combined with the history of poor hygiene and louse infestation, strongly
suggests trench fever. This disease is specifically caused by the bacterium Bartonella
quintana, which is transmitted through the bite of body lice (Pediculus humanus
corporis). The bacteria multiply within the louse's gut and are excreted in their feces.
When an infected louse bites, scratching the bite site inoculates the bacteria into the
bloodstream. Trench fever is reappearing in the homeless population in the US.
Question 6
12-year-old boy presents with a 3-day history of fever, headache, and a tender, enlarging
lymph node in his left axilla. He reports being scratched by a kitten 10 days ago. Which of
the following is the most appropriate next step in the diagnosis of this patient's condition?
A. Bartonella henselae IgM antibody test
B. Blood culture for Bartonella species
C. Chest X-ray to rule out pulmonary involvement
D. Lymph node biopsy for histopathologic examination
3
, E. PCR testing of lymph node aspirate for Bartonella DNA
CORRECT ANSWER
E. PCR testing of lymph node aspirate for Bartonella DNA
Question 7
A 25-year-old man with a history of HIV/AIDS (CD4 count: 50 cells/µL) presents with
multiple red, vascular skin lesions on his lower extremities. A skin biopsy reveals bacillary
angiomatosis. Which of the following is the most appropriate treatment for this patient's
condition?
A. Azithromycin 500 mg orally on day 1, followed by 250 mg orally daily for 4 days
B. Doxycycline 100 mg orally twice daily for 3-4 months
C. Ciprofloxacin 500 mg orally twice daily for 7 days
D. Rifampin 300 mg orally twice daily for 2 weeks
E. Trimethoprim-sulfamethoxazole 160/800 mg orally twice daily for 6 weeks
CORRECT ANSWER
B. Doxycycline 100 mg orally twice daily for 3-4 months
Question 8
A complication of Bartonella henselae & Bartonella quintana infection; seen in AIDS
patients, CD4 < 100
A. Coccidioidomycosis
B. Cryptococcosis
C. Pneumocystis pneumonia
D. Phlegmasia cerulea dolens
E. Bacillary angiomatosis
4
