NURS 615 Advanced Pharmacotherapeutics 2027 Exam 1
Questions and Answers
Question 1.
What is the process of rational drug prescribing?
Correct Answer: 1. Define the patient's problem. 2. Specify the therapeutic
objective. 3. Collaborate with the patient. 4. Choose the treatment. 5. Educate
the patient. 6. Monitor effectiveness
Question 2.
What does I Can PresCribE A Drug stand for?
Correct Answer: Indication, Contraindications, Precautions, Cost/Compliance,
Efficacy, Adverse effects, Dose/Duration/Direction
Question 3.
What are the criteria for choosing an effective drug?
Correct Answer: Use evidence-based guidelines, consider pharmacodynamics
& pharmacokinetics, determine cost- effectiveness, consider patient
preferences & adherence
Question 4.
What is passive monitoring?
Correct Answer: Patient is educated on expected outcome and instructed to
contact the provider if it doesn't happen.
Question 5.
What is active monitoring?
Correct Answer: Follow-up lab tests to measure therapeutic effectiveness.
Question 6.
What is the therapeutic window?
Correct Answer: The range between effectiveness and toxicity of a drug.
Wider=safer & less monitoring
Question 7.
What are the therapeutic factors?
Correct Answer: Evidence for therapeutic effect, safety profiles, cost, patient
factors (previous adverse reactions, health beliefs, current drug therapy, age,
, pregnancy status), ease of prescribing & monitoring (formularies), guidelines
• Who regulates prescribing? -✓✓The state boards of nursing
Question 8.
What is the Federal Food and Drug Act of 1906?
Correct Answer: The first federal law designed to protect the public;
designated that drugs must meet certain standards for strength & purity &
prohibited the manufacture of adulterated drugs. *Focused primarily on how
drugs were labeled or branded.*
Question 9.
What is the 1938 amendment to the Federal Food and Drug act?
Correct Answer: After children died from sulfa drugs; added 3
principles-restricted drug adulteration, misbranding, and interstate commerce
of unapproved drugs
Question 10.
What is the Harris-Kefauver Amendment of 1962?
Correct Answer: Due to drug thalidomide. Requires safety and efficacy of drug
to be proven before it is marketed. All drugs previously on the market were
re-evaluted.
Question 11.
What is the Orphan Drug Act of 1983?
Correct Answer: Fosters drug development for rare diseases
Question 12.
What is the Drug Price Competition and Patent Term Restoration Act of 1984?
Correct Answer: This expanded the number of generic drugs by allowing
pharmaceutical companies to prove bioequivalence rather than redoing
clinical trials (once patents expired)
Question 13.
What is the Pediatric Research Equity Act of 2003?
Correct Answer: This required pediatric studies of safety and efficacy
Question 14.
What is the Drug Quality Safety and Security Act of 2013?
Questions and Answers
Question 1.
What is the process of rational drug prescribing?
Correct Answer: 1. Define the patient's problem. 2. Specify the therapeutic
objective. 3. Collaborate with the patient. 4. Choose the treatment. 5. Educate
the patient. 6. Monitor effectiveness
Question 2.
What does I Can PresCribE A Drug stand for?
Correct Answer: Indication, Contraindications, Precautions, Cost/Compliance,
Efficacy, Adverse effects, Dose/Duration/Direction
Question 3.
What are the criteria for choosing an effective drug?
Correct Answer: Use evidence-based guidelines, consider pharmacodynamics
& pharmacokinetics, determine cost- effectiveness, consider patient
preferences & adherence
Question 4.
What is passive monitoring?
Correct Answer: Patient is educated on expected outcome and instructed to
contact the provider if it doesn't happen.
Question 5.
What is active monitoring?
Correct Answer: Follow-up lab tests to measure therapeutic effectiveness.
Question 6.
What is the therapeutic window?
Correct Answer: The range between effectiveness and toxicity of a drug.
Wider=safer & less monitoring
Question 7.
What are the therapeutic factors?
Correct Answer: Evidence for therapeutic effect, safety profiles, cost, patient
factors (previous adverse reactions, health beliefs, current drug therapy, age,
, pregnancy status), ease of prescribing & monitoring (formularies), guidelines
• Who regulates prescribing? -✓✓The state boards of nursing
Question 8.
What is the Federal Food and Drug Act of 1906?
Correct Answer: The first federal law designed to protect the public;
designated that drugs must meet certain standards for strength & purity &
prohibited the manufacture of adulterated drugs. *Focused primarily on how
drugs were labeled or branded.*
Question 9.
What is the 1938 amendment to the Federal Food and Drug act?
Correct Answer: After children died from sulfa drugs; added 3
principles-restricted drug adulteration, misbranding, and interstate commerce
of unapproved drugs
Question 10.
What is the Harris-Kefauver Amendment of 1962?
Correct Answer: Due to drug thalidomide. Requires safety and efficacy of drug
to be proven before it is marketed. All drugs previously on the market were
re-evaluted.
Question 11.
What is the Orphan Drug Act of 1983?
Correct Answer: Fosters drug development for rare diseases
Question 12.
What is the Drug Price Competition and Patent Term Restoration Act of 1984?
Correct Answer: This expanded the number of generic drugs by allowing
pharmaceutical companies to prove bioequivalence rather than redoing
clinical trials (once patents expired)
Question 13.
What is the Pediatric Research Equity Act of 2003?
Correct Answer: This required pediatric studies of safety and efficacy
Question 14.
What is the Drug Quality Safety and Security Act of 2013?
