NR 507 MIDTERM ADVANCED PATHOPHYSIOLOGY ACTUAL
PAPER SOLVED QUESTIONS
◉ What are 5 s/s of asthma
Answer: coughing
wheezing
shortness of breath
rapid breathing
chest tightness
◉ Pathophysiology of asthma (5)
Answer: -airway inflammation, bronchial hyper-reactivity and smooth muscle spasm
-excess mucus production and accumulation
,-hypertrophy of bronchial smooth muscle
-airflow obstruction
-decreased alveolar ventilation
◉ Bronchioles
Answer: smaller passageways that originate from the bronchi that become the alveoli
◉ 3 layers of the bronchioles
Answer: innermost layer
middle layer - lamina propria
outermost layer
◉ lamina propria
Answer: the middle layer of the bronchioles
,◉ structure of the lamina propria
Answer: embedded with connective tissue cells and immune cells
◉ purpose of the lamina propria
Answer: white blood cells are present to help protect the airways
◉ How does the lamina propria effect the lungs in regards to asthma
Answer: the WBCs protective feature goes into overdrive causing an inflammatory response that
damages host tissue
◉ What does the innermost layer of the bronchioles contain
Answer: columnar epithelial ells and mucus producing goblet cells
◉ What does the outermost layer of the bronchioles contain
Answer: smooth muscle cells
, ◉ what does the outermost layer of the bronchioles do
Answer: control the airways ability to constrict and dilate
◉ alveolar hyperinflation
Answer: When air is unable to move out of the alveolar like it should due to bronchial walls collapsing
around possible mucus plug thus trapping air inside
◉ how does hyperinflation occur?
Answer: the ongoing inflammatory process of asthma produces mucus and pus plug that the bronchial
walls collapse around
◉ Effect of hyperinflation of the alveolar
Answer: -expanded thorax and hypercapnia (retention of CO2)
- respiratory acidosis
PAPER SOLVED QUESTIONS
◉ What are 5 s/s of asthma
Answer: coughing
wheezing
shortness of breath
rapid breathing
chest tightness
◉ Pathophysiology of asthma (5)
Answer: -airway inflammation, bronchial hyper-reactivity and smooth muscle spasm
-excess mucus production and accumulation
,-hypertrophy of bronchial smooth muscle
-airflow obstruction
-decreased alveolar ventilation
◉ Bronchioles
Answer: smaller passageways that originate from the bronchi that become the alveoli
◉ 3 layers of the bronchioles
Answer: innermost layer
middle layer - lamina propria
outermost layer
◉ lamina propria
Answer: the middle layer of the bronchioles
,◉ structure of the lamina propria
Answer: embedded with connective tissue cells and immune cells
◉ purpose of the lamina propria
Answer: white blood cells are present to help protect the airways
◉ How does the lamina propria effect the lungs in regards to asthma
Answer: the WBCs protective feature goes into overdrive causing an inflammatory response that
damages host tissue
◉ What does the innermost layer of the bronchioles contain
Answer: columnar epithelial ells and mucus producing goblet cells
◉ What does the outermost layer of the bronchioles contain
Answer: smooth muscle cells
, ◉ what does the outermost layer of the bronchioles do
Answer: control the airways ability to constrict and dilate
◉ alveolar hyperinflation
Answer: When air is unable to move out of the alveolar like it should due to bronchial walls collapsing
around possible mucus plug thus trapping air inside
◉ how does hyperinflation occur?
Answer: the ongoing inflammatory process of asthma produces mucus and pus plug that the bronchial
walls collapse around
◉ Effect of hyperinflation of the alveolar
Answer: -expanded thorax and hypercapnia (retention of CO2)
- respiratory acidosis
