GENETICS EXAM 4 TEST BANK QUESTIONS
AND WELL VERIFIED ANSWERS ACTUAL
EXAM!!! 2026
The subunit(s) of an E. coli RNA polymerase that recognize the promoter sequence in the DNA
is/are: - ANSWER -sigma (initial step of RNA synthesis and transcription is RNA
polymerase sigma binding to promoter)
The nucleotide sequence TATAAT is commonly associated with: - ANSWER -the -10
region of bacterial chromosomes
An intrinsic transcriptional terminator in a prokaryotic cell would likely be: - ANSWER -a
nucleotide sequence that forms a hairpin with a GC-rich stem followed by a string of U's when
transcribed
The bonds that bind the alpha and beta subunits of an enzyme to each other are in fact
responsible for the protein's:
a) primary structure
b) secondary structure
c) tertiary structure
d) quaternary structure - ANSWER -secondary structure
An example of a developmentally regulated gene family would be: - ANSWER -globin
genes
Dicer and RISC are involved in the process known as: - ANSWER -RNA [gene] silencing
Which of the following is NOT an example of a posttranslational modification? a) N-terminal
amino acid(s) commonly removed or modified b) Signal/targeting peptide removal c)
Phosphorylation, methylation, acetylation d) glycosylation e) All of the above are example of
PM - ANSWER -All of the above are examples of posttranslational modifications
, Which of the following is NOT an example of a posttranscriptional modification? a) Capping the
5' end of a pre-mRNA b) intron removal c) RNA editing d) addition of poly(a) to the 5' end of a
pre-mRNA e) all of the above are correct examples - ANSWER -e) all of the the above are
correct examples of common posttranscriptional modifications of RNAs in higher Eukaryotes
The simple test used to assess mutagenicity of compounds using Salmonella auxotrophs was
developed by: - ANSWER -Bruce Ames
Transposable elements were first discovered by Barbara McClintock who was studying what
organism? - ANSWER -Zea Mays
A human genetic disorder that results from an inability to carry out excision repair of
pyrimidine dimers is: - ANSWER -xeroderma pigmentosum
A human gene is found to have a number of CpG dinucleotides that are methylated at the C
base. It is very likely that this gene: - ANSWER -is turned off
A very strong indicator that cancer involves the mutation of multiple genes is the fact that: -
ANSWER -The annual incidence rate of all forms of cancer goes up with age
A group of genes that normally regulate cell cycle checkpoints and/or initiate the process of
apoptosis would be the: - ANSWER -signal transduction pathway encoding genes
An enhanceosome is very likely to have: - ANSWER -DNA-binding domain
In the context of the trp operon of E. coli, the molecule tryptophan is the: - ANSWER -
corepressor
The single human gene whose mutation is associated most commonly with the cancerous state
is: - ANSWER -p53
An example of gene expression that is regulated by altering the half-life of the mRNA is: -
ANSWER -Tubulin expression in eukaryotes
AND WELL VERIFIED ANSWERS ACTUAL
EXAM!!! 2026
The subunit(s) of an E. coli RNA polymerase that recognize the promoter sequence in the DNA
is/are: - ANSWER -sigma (initial step of RNA synthesis and transcription is RNA
polymerase sigma binding to promoter)
The nucleotide sequence TATAAT is commonly associated with: - ANSWER -the -10
region of bacterial chromosomes
An intrinsic transcriptional terminator in a prokaryotic cell would likely be: - ANSWER -a
nucleotide sequence that forms a hairpin with a GC-rich stem followed by a string of U's when
transcribed
The bonds that bind the alpha and beta subunits of an enzyme to each other are in fact
responsible for the protein's:
a) primary structure
b) secondary structure
c) tertiary structure
d) quaternary structure - ANSWER -secondary structure
An example of a developmentally regulated gene family would be: - ANSWER -globin
genes
Dicer and RISC are involved in the process known as: - ANSWER -RNA [gene] silencing
Which of the following is NOT an example of a posttranslational modification? a) N-terminal
amino acid(s) commonly removed or modified b) Signal/targeting peptide removal c)
Phosphorylation, methylation, acetylation d) glycosylation e) All of the above are example of
PM - ANSWER -All of the above are examples of posttranslational modifications
, Which of the following is NOT an example of a posttranscriptional modification? a) Capping the
5' end of a pre-mRNA b) intron removal c) RNA editing d) addition of poly(a) to the 5' end of a
pre-mRNA e) all of the above are correct examples - ANSWER -e) all of the the above are
correct examples of common posttranscriptional modifications of RNAs in higher Eukaryotes
The simple test used to assess mutagenicity of compounds using Salmonella auxotrophs was
developed by: - ANSWER -Bruce Ames
Transposable elements were first discovered by Barbara McClintock who was studying what
organism? - ANSWER -Zea Mays
A human genetic disorder that results from an inability to carry out excision repair of
pyrimidine dimers is: - ANSWER -xeroderma pigmentosum
A human gene is found to have a number of CpG dinucleotides that are methylated at the C
base. It is very likely that this gene: - ANSWER -is turned off
A very strong indicator that cancer involves the mutation of multiple genes is the fact that: -
ANSWER -The annual incidence rate of all forms of cancer goes up with age
A group of genes that normally regulate cell cycle checkpoints and/or initiate the process of
apoptosis would be the: - ANSWER -signal transduction pathway encoding genes
An enhanceosome is very likely to have: - ANSWER -DNA-binding domain
In the context of the trp operon of E. coli, the molecule tryptophan is the: - ANSWER -
corepressor
The single human gene whose mutation is associated most commonly with the cancerous state
is: - ANSWER -p53
An example of gene expression that is regulated by altering the half-life of the mRNA is: -
ANSWER -Tubulin expression in eukaryotes
