_!#~@Page
@~~!@#)_________!#~@Page
2026/10/05@~~!@#)_________!#~@Page
1 of 1710/5/2026, 5:02:10
1 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
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AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566
NR566 Final Study Guide
Be familiar with the interactive activities throughout course modules. You could see
variations of those same questions on your exams.
Week 5
Complete the following table to study/prepare for the treatment of STIs/STDs according to
National STD curriculum completed in Week 5 of the course.
STI/STD First line drug, dose, route, frequency
Chlamydia Doxycycline 100mg PO BID x 7 days
(Among Adolescents and Adults) Alternative = Azithromycin 1G PO once
Uncomplicated gonococcal urethritis Ceftriaxone 250mg IM once (+) Azithromycin 1G PO once
Bacterial Vaginosis Metronidazole 500mg PO BID x 7 days OR
Metronidazole gel (.75%) 1 full applicator intravaginally X 5
days
Herpes Simplex Virus Acyclovir 400mg PO TID x 7-10 days
(First Clinical Episode)
Pelvic Inflammatory Disease (PID) (IM or Oral Doxycycline 100mg PO BID x 14 days (+) Cefoxitin 2mg IM
Regimens) OR Ceftriaxone 250mg IM (+ if severe) w/ or w/o metronidazole
500mg PO BIDx 14 days
Syphilis Benzathine penicillin G 2.4 million units IM single dose
(Primary and Secondary)
• Doxazosin (Cardura)
o BPH medication: alpha blocker
o Side Effects
▪ Hypotension
• Caution in patients taking nitro, antihypertensives and PDE 5-
inhibitors
▪ Fainting
▪ Dizziness
▪ Somnolence
▪ Nasal Congestion
▪ Floppy eye syndrome – complications due to cataract surgery recovery
• Dutasteride
o Used to reduce symptoms of BPH
o Patient teaching and response to delayed onset of therapeutic effect
▪ Side effect: Reduces ejaculate volume and libido
▪ Men cannot donate blood for 6 months after stopping to avoid
transmission to female partners – it takes months to clear the drug from
the system
_!#~@Page
@#)_________!#~@Page
20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx@~~!@#)_________!#~@Page
1 of 1710/5/2026,
1 of5:02:10
1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide
1 of 1710/5/2026, 5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&
,_!#~@Page
@~~!@#)_________!#~@Page
2026/10/05@~~!@#)_________!#~@Page
2 of 1710/5/2026, 5:02:10
2 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10
2 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566
NR566 Final Study Guide
▪
Capsule MUST be swallowed whole to avoid damage to oropharyngeal
mucosa
▪ Results can take 6- 12 months to occur, and prostate shrinkage occurs
slowly
▪ Evaluate PSA @ 6 months- if no change, evaluate for prostate CA
▪ Can be absorbed through skin
▪ Is teratogenic- drug should not be handled by pregnant women
• Terazosin – alpha agonist: relaxes smooth muscle in bladder and decreased obstruction
of urethra
o How to know it’s working
▪ Improvement and increased urinary flow occur rapidly
• Various routes of administration of estrogen therapy and when each would be
used
o Oral
▪ Most convenient route
▪ Used more than any other route
▪ Estradiol available alone OR combo with progestins
o Transdermal
▪ Spray: applied daily to inner forearms
▪ Emulsion: applied daily to top of thighs and back of calves
▪ Gel: applied daily to one arm from shoulder to wrist
▪ Patches: apply to trunk region (not breast or waistline)
o Highly advantageous due to:
▪ less n/v
▪ decreased fluctuation of estrogen blood levels
▪ lower risk for DVT
▪ total estrogen dose greatly reduced (bypasses
liver)
o Intravaginal
▪ Inserts, creams, and rings
▪ Only used for local effects
• Vulva and vaginal atrophy
▪ Fem-ring can be used for systemic effects (hot flashes and night sweats)
AND local effects
o Parenteral
▪ IV and IM routes rarely used
▪ IV usually reserved for control of emergent heavy bleeding
• When is it safe and not safe to prescribe progesterone (AKA: progestin)
o Progestin is ONLY indicated if the patient has a uterus
o Contraindications:
▪ Active thrombophlebitis (blood clot that causes inflammation and pain)
▪ Hx of thrombolytic disorder
▪ Active liver dz
▪ Breast CA
▪ NOT indicated for undiagnosed vaginal bleeding
o Side effects of progestin-only oral contraceptives
▪ Side effects:
_!#~@Page
@#)_________!#~@Page
20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx@~~!@#)_________!#~@Page
2 of 1710/5/2026,
2 of5:02:10
1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide
2 of 1710/5/2026, 5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&
,_!#~@Page
@~~!@#)_________!#~@Page
2026/10/05@~~!@#)_________!#~@Page
3 of 1710/5/2026, 5:02:10
3 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10
3 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566
NR566 Final Study Guide
• Less effective form of BC
• Irregular bleeding (spotting, cycle inconsistencies, amenorrhea)
▪ MUST be taken at same time every day – effectiveness can be greatly
reduced if not
▪ Must use backup for 1st 7 days of initiating therapy
▪ Must use backup if administration is inconsistent
• Benefits of prescribing medroxyprogesterone acetate (Depo-Provera)
o Injection occurs only 1 time every 3 months
o When d/c’d fertility is delayed by 3 months
o Reduces the risk of endometrial cancer
• Testosterone therapy
o Patient teaching in general
▪ Avoid contact with user’s skin where testosterone was applied
▪ Wash contaminated skin if accidental application occurs
▪ Female virilization
• Deepening of voice, acne, body hair changes, cycle irregularities
▪ Report all s/s of liver dysfunction
• Jaundice to eyes or skin
• Fatigue
• Appetite loss
• Nausea
• Dark urine/ light stools
▪ Report swelling of extremities or unusual weight gain
▪ Need to use reliable contraception if female b/c therapy can cause fetal
malformations
▪ Risk for thromboembolic events
• Consider teaching specific to different routes
o Oral Therapy
▪ Not first line agents
▪ Risk for hepatoxicity
o Transdermal
▪ Patches are applied once daily to upper arms, thigh, back or abdomen
▪ Side effects mostly = rash
▪ Gels can cause less irritation and deliver more consistent testosterone
▪ Gels must be washed off if contact occurs in women or children
▪ Gel users = wash hands after application and cover skin with clothing
once dried
▪ Should wait 5-6 hours after gel application to shower/swim
▪ Testosterone measurement should occur after 14 days
▪ Avoid smoking/ flames due to flammability of preparations
o Nasal Gel
▪ Contraindicated in patients with septal deviation or chronic sinusitis
▪ Can cause irritation = rhinorrhea, epistaxis, or nasopharyngitis
▪ Blow nose before administration
▪ Massage below nasal bridge after administration
▪ Avoid blowing nose for 1 hr after
_!#~@Page
@#)_________!#~@Page
20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx@~~!@#)_________!#~@Page
3 of 1710/5/2026,
3 of5:02:10
1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide
3 of 1710/5/2026, 5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&
@~~!@#)_________!#~@Page
2026/10/05@~~!@#)_________!#~@Page
1 of 1710/5/2026, 5:02:10
1 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10
1 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566
NR566 Final Study Guide
Be familiar with the interactive activities throughout course modules. You could see
variations of those same questions on your exams.
Week 5
Complete the following table to study/prepare for the treatment of STIs/STDs according to
National STD curriculum completed in Week 5 of the course.
STI/STD First line drug, dose, route, frequency
Chlamydia Doxycycline 100mg PO BID x 7 days
(Among Adolescents and Adults) Alternative = Azithromycin 1G PO once
Uncomplicated gonococcal urethritis Ceftriaxone 250mg IM once (+) Azithromycin 1G PO once
Bacterial Vaginosis Metronidazole 500mg PO BID x 7 days OR
Metronidazole gel (.75%) 1 full applicator intravaginally X 5
days
Herpes Simplex Virus Acyclovir 400mg PO TID x 7-10 days
(First Clinical Episode)
Pelvic Inflammatory Disease (PID) (IM or Oral Doxycycline 100mg PO BID x 14 days (+) Cefoxitin 2mg IM
Regimens) OR Ceftriaxone 250mg IM (+ if severe) w/ or w/o metronidazole
500mg PO BIDx 14 days
Syphilis Benzathine penicillin G 2.4 million units IM single dose
(Primary and Secondary)
• Doxazosin (Cardura)
o BPH medication: alpha blocker
o Side Effects
▪ Hypotension
• Caution in patients taking nitro, antihypertensives and PDE 5-
inhibitors
▪ Fainting
▪ Dizziness
▪ Somnolence
▪ Nasal Congestion
▪ Floppy eye syndrome – complications due to cataract surgery recovery
• Dutasteride
o Used to reduce symptoms of BPH
o Patient teaching and response to delayed onset of therapeutic effect
▪ Side effect: Reduces ejaculate volume and libido
▪ Men cannot donate blood for 6 months after stopping to avoid
transmission to female partners – it takes months to clear the drug from
the system
_!#~@Page
@#)_________!#~@Page
20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx@~~!@#)_________!#~@Page
1 of 1710/5/2026,
1 of5:02:10
1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide
1 of 1710/5/2026, 5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&
,_!#~@Page
@~~!@#)_________!#~@Page
2026/10/05@~~!@#)_________!#~@Page
2 of 1710/5/2026, 5:02:10
2 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10
2 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566
NR566 Final Study Guide
▪
Capsule MUST be swallowed whole to avoid damage to oropharyngeal
mucosa
▪ Results can take 6- 12 months to occur, and prostate shrinkage occurs
slowly
▪ Evaluate PSA @ 6 months- if no change, evaluate for prostate CA
▪ Can be absorbed through skin
▪ Is teratogenic- drug should not be handled by pregnant women
• Terazosin – alpha agonist: relaxes smooth muscle in bladder and decreased obstruction
of urethra
o How to know it’s working
▪ Improvement and increased urinary flow occur rapidly
• Various routes of administration of estrogen therapy and when each would be
used
o Oral
▪ Most convenient route
▪ Used more than any other route
▪ Estradiol available alone OR combo with progestins
o Transdermal
▪ Spray: applied daily to inner forearms
▪ Emulsion: applied daily to top of thighs and back of calves
▪ Gel: applied daily to one arm from shoulder to wrist
▪ Patches: apply to trunk region (not breast or waistline)
o Highly advantageous due to:
▪ less n/v
▪ decreased fluctuation of estrogen blood levels
▪ lower risk for DVT
▪ total estrogen dose greatly reduced (bypasses
liver)
o Intravaginal
▪ Inserts, creams, and rings
▪ Only used for local effects
• Vulva and vaginal atrophy
▪ Fem-ring can be used for systemic effects (hot flashes and night sweats)
AND local effects
o Parenteral
▪ IV and IM routes rarely used
▪ IV usually reserved for control of emergent heavy bleeding
• When is it safe and not safe to prescribe progesterone (AKA: progestin)
o Progestin is ONLY indicated if the patient has a uterus
o Contraindications:
▪ Active thrombophlebitis (blood clot that causes inflammation and pain)
▪ Hx of thrombolytic disorder
▪ Active liver dz
▪ Breast CA
▪ NOT indicated for undiagnosed vaginal bleeding
o Side effects of progestin-only oral contraceptives
▪ Side effects:
_!#~@Page
@#)_________!#~@Page
20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx@~~!@#)_________!#~@Page
2 of 1710/5/2026,
2 of5:02:10
1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide
2 of 1710/5/2026, 5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&
,_!#~@Page
@~~!@#)_________!#~@Page
2026/10/05@~~!@#)_________!#~@Page
3 of 1710/5/2026, 5:02:10
3 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
5:02:10
3 of 1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_
5:02:10 AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566
NR566 Final Study Guide
• Less effective form of BC
• Irregular bleeding (spotting, cycle inconsistencies, amenorrhea)
▪ MUST be taken at same time every day – effectiveness can be greatly
reduced if not
▪ Must use backup for 1st 7 days of initiating therapy
▪ Must use backup if administration is inconsistent
• Benefits of prescribing medroxyprogesterone acetate (Depo-Provera)
o Injection occurs only 1 time every 3 months
o When d/c’d fertility is delayed by 3 months
o Reduces the risk of endometrial cancer
• Testosterone therapy
o Patient teaching in general
▪ Avoid contact with user’s skin where testosterone was applied
▪ Wash contaminated skin if accidental application occurs
▪ Female virilization
• Deepening of voice, acne, body hair changes, cycle irregularities
▪ Report all s/s of liver dysfunction
• Jaundice to eyes or skin
• Fatigue
• Appetite loss
• Nausea
• Dark urine/ light stools
▪ Report swelling of extremities or unusual weight gain
▪ Need to use reliable contraception if female b/c therapy can cause fetal
malformations
▪ Risk for thromboembolic events
• Consider teaching specific to different routes
o Oral Therapy
▪ Not first line agents
▪ Risk for hepatoxicity
o Transdermal
▪ Patches are applied once daily to upper arms, thigh, back or abdomen
▪ Side effects mostly = rash
▪ Gels can cause less irritation and deliver more consistent testosterone
▪ Gels must be washed off if contact occurs in women or children
▪ Gel users = wash hands after application and cover skin with clothing
once dried
▪ Should wait 5-6 hours after gel application to shower/swim
▪ Testosterone measurement should occur after 14 days
▪ Avoid smoking/ flames due to flammability of preparations
o Nasal Gel
▪ Contraindicated in patients with septal deviation or chronic sinusitis
▪ Can cause irritation = rhinorrhea, epistaxis, or nasopharyngitis
▪ Blow nose before administration
▪ Massage below nasal bridge after administration
▪ Avoid blowing nose for 1 hr after
_!#~@Page
@#)_________!#~@Page
20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx@~~!@#)_________!#~@Page
3 of 1710/5/2026,
3 of5:02:10
1710/5/2026,
AM&@*&#^*^($(@*^$&*&(*^$$&$&*$^^&&@&*^$&^20240402132334_660c06d6213c0_nr566_final_exam_study_guide.docx
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