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Test Bank - Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), 9781975222321, Chapter 1-61 All Chapters

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Test Bank - Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), 9781975222321, Chapter 1-61 All Chapters

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ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
n7 n7 n7 n7 n7




NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
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n7 TESTBANK/COMPLETE GUIDE 2026-2027ALL CHAPTERS 1-61
n7 n7 n7 n7

,Chapter 1: The Foundation of Pharmacology: Quality and Safety
n7 n7 n7 n7 n7 n7 n7 n7




1. A patient diagnosed with obsessive–compulsive disorder has been prescribed
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oralparoxetine hydrochloride. What is the expected effect for this
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prescription?
n7


A. Curative effect on symptoms n7 n7 n7


B. Systemic effect on symptoms n7 n7 n7


C. Local effect on symptoms n7 n7 n7


D. Parenteral effect on symptoms n7 n7 n7




ACCURATE ANSWER:-B n7


REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into n7 n7 n7 n7 n7 n7 n7 n7


the body, circulated through the bloodstream to their sites of action in various body
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


tissues, and eventually eliminated from the body. Curative agents are given to cure a
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


disease process. Inthis case, paroxetine hydrochloride will control the symptoms but
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


not cure the disorder.
n7 n7 n7 n7


Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


mainly at the site of application. Paroxetine hydrochloride is not administered
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
n7 n7 n7 7
n n7 n7 n7 n7


intravenously.
n7




POINTS: 1 REFERENCE: p. 3, Introduction n7 n7 OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
n7 n7 n7 n7 n7 n7 n7


Parenteral TherapiesTOP:
n7 Chapter: 1: The Foundation of Pharmacology:
n7 n7 n7 n7 n7 n7 n7


Quality and Safety
n7 n7 n7


KEY: Integrated Process: Nursing Process
n7 n7 n7 n7


BLM: Cognitive Level: Understand
n 7 NOT: Multiple Choice n7 n7 n7 n7




2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


is a naturally occurring substance that has been cheG
n7 n7 n7 mRicA
alDlyEm
SoBdOifOieSd.TW
n7
.C
haOt Mi s n7 n7 n7 n7 n7 n7 n7 n7 n7


another name for this type of pharmaceutical drug?
n7 n7 n7 n7 n7 n7 n7 n7


A. Synthetic drug n7


B. Semisynthetic drug n7


C. Biotechnology drug n7


D. Prototype drug n7




ACCURATE ANSWER:-B n7


REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are n7 n7 n7 n7 n7 n7


naturally occurring substances that have been chemically modified. Synthetic
n7 n7 n7 n7 n7 n7 n7 n7 n7


pharmaceutical drug are more standardized in their chemical characteristics, more
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consistent in their effects, and less likely to produce allergic reactions.
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


Biotechnology pharmaceutical drug involve manipulating DNAand RNA and
n7 n7 n7 n7 n7 n7 7
n n7 n7


recombining genes into hybrid molecules that can be inserted into living organisms.
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


Prototype pharmaceutical drug are the first drug of a particular group to be
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developed.
n7




POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: 1 n7 n7 n7


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
n7 n7 n7 n7 n7 n7 n7


Parenteral TherapiesTOP:
n7 Chapter: 1: The Foundation of Pharmacology:
n7 n7 n7 n7 n7 n7 n7


Quality and Safety
n7 n7 n7


KEY: Integrated Process: Nursing Process
n7 n7 n7 n7


BLM: Cognitive Level: Understand
n 7 NOT: Multiple Choice n7 n7 n7 n7




3. Which classification applies to morphine?
n7 n7 n7 n7


A. Central nervous system depressant n7 n7 n7


B. Central nervous system stimulant n7 n7 n7

, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A n7


REASONING:->>>Pharmaceutical drug are classified according to their effects on n7 n7 n7 n7 n7 n7 n7 n7


particular body systems, their therapeutic uses, and their chemical characteristics.
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


Morphine is classified as a central nervous system depressant and will produce this
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effect in the hospital client. Acentral nervous system stimulant increases attention and
n7 n7 n7 n7 n7 n7 7
n n7 n7 n7 n7 n7 n7


raises mood. An anti-inflammatoryagent decreases inflammation at the site of tissue or
n7 n7 n7 n7 7
n n7 n7 n7 n7 n7 n7 n7 n7


joint inflammation. An antihypertensiveagent reduces blood pressure.
n7 n7 n7 n7 7
n n7 n7 n7




POINTS: 1 REFERENCE: p. 3, Drug n7 n7


Classifications and PrototypesOBJ:
n7 1 n7 n7 7
n


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
n7 n7 n7 n7 n7 n7 n7


Parenteral TherapiesTOP:
n7 Chapter: 1: The Foundation of Pharmacology:
n7 n7 n7 n7 n7 n7 n7


Quality and Safety
n7 n7 n7


KEY: Integrated Process: Nursing Process
n7 n7 n7 n7


BLM: Cognitive Level: Remember
n 7 NOT: Multiple Choice n7 n7 n 7 n7




4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical
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drug belongs to whichdrug group?
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A. Selective serotonin reuptake inhibitors n7 n7 n7


B. Diuretics
C. Penicillins
D. ACE inhibitors n7




ACCURATE ANSWER:-C n7


REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
GRADESBOOST.CO
with generic names ending in ―cillin‖ are penicillins). Selective serotonin
n7 n7 n7
n7


n7 n7
n7 n7


n7 n7
n7 n7


n7
n7 n7


n7
n7 n7 n7




reuptakeinhibitors are pharmaceutical drugs
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that have antidepressant effects; SSRI is a broad classification, not a generic name.
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


Diureticsare pharmaceutical drugs that increase urine output; diuretic is a broad
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


classification, not a generic name. ACE inhibitor is the broad classification for the
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angiotensin receptor blockers, not thegeneric name.
n7 n7 n7 n7 n7 7
n n7




POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: 2 n7 n7 n7


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
n7 n7 n7 n7 n7 n7 n7


Parenteral TherapiesTOP:
n7 Chapter: 1: The Foundation of Pharmacology:
n7 n7 n7 n7 n7 n7 n7


Quality and Safety
n7 n7 n7


KEY: Integrated Process: Nursing Process
n7 n7 n7 n7


BLM: Cognitive Level: Understand
n 7 NOT: Multiple Choice n7 n7 n7 n7




5. The administration of diphenhydramine is regulated by which U.S. government agency?
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


A. Public Health Service n7 n7


B. Federal Trade Commission n7 n7


C. Occupational Safety and Health Administration n7 n7 n7 n7


D. Food and n7




n7 DrugAdministrati
n7




on

ACCURATE ANSWER:-D n7

, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug n7 n7 n7 n7 n7 n7 n7


for over- the-counter availability, including the transfer of pharmaceutical drug from
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


prescription to OTC status, and may require clinical trials to determine the safety and
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


effectiveness of OTC use.The Public Health Service is regulated by the state to
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maintain the health of individual citizens of the state. The Federal Trade
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Commission regulates imports and exports throughout the nation. The Occupational
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Safety and Health Administration regulates safetywithin the workplace.
n7 n7 n7 n7 n7 n7 7
n n7 n7




POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription n7 n7 n7 n7


Pharmaceutical drug OBJ:4 n7 n7


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
n7 n7 n7 n7 n7 n7 n7


Parenteral TherapiesTOP:
n7 Chapter: 1: The Foundation of Pharmacology:
n7 n7 n7 n7 n7 n7 n7


Quality and Safety
n7 n7 n7


KEY: Integrated Process: Nursing Process
n7 n7 n7 n7


BLM: Cognitive Level: Understand
n 7 NOT: Multiple Choice n7 n7 n7 n7




6. In n7 the U.S., the administration of anabolic steroids is regulated by which law?
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


A. The Food, Drug, and Cosmetic Act of 1938
n7 n7 n7 n7 n7 n7 n7


B. The Comprehensive Drug Abuse Prevention and Control Act
n7 n7 n7 n7 n7 n7 n7


C. The Harrison Narcotic Act
n7 n7 n7


D. The Sherley Amendmentn7 n7




ACCURATE ANSWER:-B n7


REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act n7 n7 n7 n7 n7 n7 n7


regulates the manufacture and distribution of narcotics, stimulants, depressants,
n7 n7 n7 n7 n7 n7 n7 n7 n7


hallucinogens, and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


revised and broadened FDA powers and responsibilities, giving the FDA control over
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale,
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


and use of opium,cocaine, marijuana, and other pharmaceutical drug that the act d e f i Gn
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


eRd AaDs E
n7 naSrcBoO
tiO
csS Th.eCSOhM
. T erley Amendment of 1912 prohibited fraudulent claims of drug
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


effectiveness.
n7




POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription n7 n7 n7 n7


Pharmaceutical drug OBJ: 3 n7 n7


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
n7 n7 n7 n7 n7 n7 n7


Parenteral TherapiesTOP:
n7 Chapter: 1: The Foundation of Pharmacology:
n7 n7 n7 n7 n7 n7 n7


Quality and Safety
n7 n7 n7


KEY: Integrated Process: Nursing Process
n7 n7 n7 n7


BLM: Cognitive Level: Remember
n 7 NOT: Multiple Choice n7 n7 n 7 n7




7. A nursing attendant is responsible for maintaining an accurate count and record of
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


the controlled substances on the nursing division. This nursing action is regulated
n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7 n7


by which
n7 n7


U.S. law or agency?
n7 n7 n7


A. The Food, Drug, and Cosmetic Act of 1938
n7 n7 n7 n7 n7 n7 n7


B. The Public Health Service n7 n7 n7


C. The Drug Enforcement Administration
n7 n7 n7


D. The Sherley n7




AmendmentACCURATE
n7 n7




n7 ANSWER:-C

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Frandsen, Sandra Smith Pennington Abrams\' Clinical Drug Therapy
Publisher: 2024 ISBN: 9781975222321 Edition: Unknown

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