Test bank for Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition by Nader Rifai, PhD Chapters 1 - 49

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Test bank for Tietz Fundamentals of Clinical Chemistry
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and Molecular Diagnostics 8th Edition b
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yNader Rifai, PhD Chapters 1 - 49
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Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
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Table of contents: gh gh




I. Principles Of Laboratory Medicine
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Chapter 1. ClinicalChemistry, Molecular Diagnostics, and LaboratoryMedicine
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Chapter 2. Selection and AnalyticalEvaluation of Methods — With StatisticalTechniques
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Chapter 3. ClinicalEvaluation of Methods
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Chapter 4. Evidence-Based LaboratoryMedicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other PreanalyticalVariables
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Chapter 7. QualityManagement gh gh gh




II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and LaboratorySafety
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Chapter 9. OpticalTechniques gh gh gh




Chapter 10. Electrochemistryand Chemical Sensors
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Chapter 11. Electrophoresis gh gh




Chapter 12. Chromatography gh gh




Chapter 13. Mass Spectrometry gh gh gh




Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation gh gh




Chapter 17. Point-of-Care Instrumentation
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III. Analytesghgh




Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. SerumEnzymes gh gh gh




Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates gh gh




Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones gh gh




Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. ClinicalToxicologygh gh gh




Chapter 32. Toxic Metals gh g h gh




IV. Pathophysiology
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Chapter 33. Diabetes gh gh

,Chapter 34. Cardiovascular Disease
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Chapter 35. KidneyDisease
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Chapter 36. Physiologyand Disorders ofWater, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders ofBone and Mineral Metabolism
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Chapter 40. Disorders ofthe PituitaryGland
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Chapter 41. Disorders ofthe Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancyand PrenatalTesting
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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Chapter01: Clinical Chemistry, Molecular Diagnostics, andLaboratory Medicine TestBank
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MULTIPLE CHOICE gh




1. An individual working in a clinical chemistry laboratory is married to a sales representative who works
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for a company that sells chemistry laboratorysupplies. When the laboratory manager requests a list o
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f needed supplies, cost of supplies, and vendors, this individual only recommends the spouse’s compa
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nyas the vendor. This is considered to be a(n):
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a. accounting issue. gh




b. possible conflict ofinterest. gh g h gh




c. maintenance ofconfidentialityissue. gh gh gh




d. problemwith resource allocation. gh gh gh




ANS: B g h




Concernhas been raised over the interrelationships betweenpractitioners in the medical field and co
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mmercialsuppliers ofdrugs, devices, equipment, etc., to the medical profession. gh gh gh gh gh gh gh gh gh gh




Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers and prgh gh g h gh gh gh gh gh g h gh gh




oviders ofdiagnostic equipment and supplies. These concerns led the National Institutes of Health (NI
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H) in 1995 to require official institutionalreview of financial disclosurebyresearchers and managemen
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t ofsituations inwhich disclosure indicates potential conflicts of interest.
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2. A patient visits her physician stating that her prescribed painkiller is not working to reduce the pain f
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ollowing her recent surgery. A friend of the patient claims that the same painkiller ―worked wonder
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s‖ to reduce her pain after the same surgery. The physician states that the difference in the effect of t
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he drug might be caused by
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, which is studied in pharmacogenetics.
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a. epidemiology
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c. aconflict ofinterest gh gh gh




d. agenetic variation in drug-metabolizing enzymes
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ANS: D g h




Pharmacogenetics is the studyofthe genetic variationofdrug metabolism between individuals. gh gh gh gh gh gh gh gh gh gh gh g h




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3. John works in a molecular diagnostics laboratoryand receives a blood sample that has the name ofa
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close friend printed onthe bar- gh gh gh gh gh




coded label. The genetic test that isordered on the friend’s sample would provide diagnostic inform
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ation about a disorder that has a poor prognosis, and the test is usuallyperformed by John. He asks a
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fellow employee to analyze the sample for him and not divulge the results. This ethical issue concern
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s:
a. confidentialityofpatient genetic and medicalinformation. gh gh g h gh g h gh




b. aconflict of interest. gh g h gh