HESI LPN-to-ADN Entrance Exam – Questions with
Answers & Explanations | Latest 2026 LPN to RN
Transition Study Guide
Description
HESI LPN-to-ADN Entrance Exam – Latest 2026 prep with 250 multiple-choice
questions, verified answers, and detailed explanations. Covers mathematics, reading
comprehension, vocabulary, grammar, anatomy & physiology, biology, chemistry,
and critical thinking. Perfect for LPN to RN transition and guaranteed pass. Instant
PDF download.
SECTION 1: MATHEMATICS (Questions 1–50)
1. A patient is prescribed 250 mg of a medication. The pharmacy sends a bottle
labeled 100 mg/2 mL. How many mL should the nurse administer?
A. 2.5 mL
B. 4 mL
C. 5 mL
D. 10 mL
Answer: C. Using the ratio: Desired/Have × Quantity. (250 mg / 100 mg) × 2 mL = 2.5 × 2 =
5 mL.
,2. Convert 0.45 to a simplified fraction.
A. 45/100
B. 9/20
C. 4/5
D. 1/2
Answer: B. 0.45 equals 45/100. The greatest common divisor of 45 and 100 is 5. Divide
both by 5 to get 9/20.
3. A patient weighs 154 lbs. What is the patient's weight in kilograms? (Round to the
nearest tenth).
A. 68.2 kg
B. 70.0 kg
C. 75.5 kg
D. 80.0 kg
Answer: B. To convert pounds to kilograms, divide the weight in pounds by 2.2. 154 ÷ 2.2 =
70.0 kg.
4. An IV is infusing at 75 mL/hour. How many mL will the patient receive in 4 hours?
A. 150 mL
B. 200 mL
C. 300 mL
D. 450 mL
Answer: C. 75 mL/hour × 4 hours = 300 mL.
5. What is 25% of 80?
A. 15
B. 20
,C. 25
D. 30
Answer: B. 0.25 × 80 = 20.
6. Convert 2.5 L to milliliters.
A. 25 mL
B. 250 mL
C. 2,500 mL
D. 25,000 mL
Answer: C. 1 L equals 1,000 mL, so 2.5 L equals 2,500 mL.
7. How many teaspoons are in 1 tablespoon?
A. 2
B. 3
C. 4
D. 5
Answer: B. One tablespoon is equivalent to three teaspoons.
8. A medication is prescribed at 500 mg. Tablets available are 250 mg each. How
many tablets should be given?
A. 0.5
B. 1
C. 2
D. 3
Answer: C. 500 ÷ 250 = 2 tablets.
, 9. What is 7 × 8?
A. 48
B. 54
C. 56
D. 64
Answer: C. 7 multiplied by 8 equals 56.
10. What is the greatest common factor of 18 and 24?
A. 3
B. 6
C. 8
D. 12
Answer: B. Six is the largest number that divides evenly into both 18 and 24.
11. A patient weighs 180 pounds. How many kilograms is this? (Round to the nearest
tenth.)
A. 81.6 kg
B. 82.0 kg
C. 79.4 kg
D. 80.0 kg
Answer: A. 1 kg = 2.2 lbs. 180 ÷ 2.2 = 81.818, rounded to 81.6 kg.
12. The physician orders 500 mg of a medication. The available tablet is 250 mg. How
many tablets will you administer?
A. 1 tablet
B. 1.5 tablets
Answers & Explanations | Latest 2026 LPN to RN
Transition Study Guide
Description
HESI LPN-to-ADN Entrance Exam – Latest 2026 prep with 250 multiple-choice
questions, verified answers, and detailed explanations. Covers mathematics, reading
comprehension, vocabulary, grammar, anatomy & physiology, biology, chemistry,
and critical thinking. Perfect for LPN to RN transition and guaranteed pass. Instant
PDF download.
SECTION 1: MATHEMATICS (Questions 1–50)
1. A patient is prescribed 250 mg of a medication. The pharmacy sends a bottle
labeled 100 mg/2 mL. How many mL should the nurse administer?
A. 2.5 mL
B. 4 mL
C. 5 mL
D. 10 mL
Answer: C. Using the ratio: Desired/Have × Quantity. (250 mg / 100 mg) × 2 mL = 2.5 × 2 =
5 mL.
,2. Convert 0.45 to a simplified fraction.
A. 45/100
B. 9/20
C. 4/5
D. 1/2
Answer: B. 0.45 equals 45/100. The greatest common divisor of 45 and 100 is 5. Divide
both by 5 to get 9/20.
3. A patient weighs 154 lbs. What is the patient's weight in kilograms? (Round to the
nearest tenth).
A. 68.2 kg
B. 70.0 kg
C. 75.5 kg
D. 80.0 kg
Answer: B. To convert pounds to kilograms, divide the weight in pounds by 2.2. 154 ÷ 2.2 =
70.0 kg.
4. An IV is infusing at 75 mL/hour. How many mL will the patient receive in 4 hours?
A. 150 mL
B. 200 mL
C. 300 mL
D. 450 mL
Answer: C. 75 mL/hour × 4 hours = 300 mL.
5. What is 25% of 80?
A. 15
B. 20
,C. 25
D. 30
Answer: B. 0.25 × 80 = 20.
6. Convert 2.5 L to milliliters.
A. 25 mL
B. 250 mL
C. 2,500 mL
D. 25,000 mL
Answer: C. 1 L equals 1,000 mL, so 2.5 L equals 2,500 mL.
7. How many teaspoons are in 1 tablespoon?
A. 2
B. 3
C. 4
D. 5
Answer: B. One tablespoon is equivalent to three teaspoons.
8. A medication is prescribed at 500 mg. Tablets available are 250 mg each. How
many tablets should be given?
A. 0.5
B. 1
C. 2
D. 3
Answer: C. 500 ÷ 250 = 2 tablets.
, 9. What is 7 × 8?
A. 48
B. 54
C. 56
D. 64
Answer: C. 7 multiplied by 8 equals 56.
10. What is the greatest common factor of 18 and 24?
A. 3
B. 6
C. 8
D. 12
Answer: B. Six is the largest number that divides evenly into both 18 and 24.
11. A patient weighs 180 pounds. How many kilograms is this? (Round to the nearest
tenth.)
A. 81.6 kg
B. 82.0 kg
C. 79.4 kg
D. 80.0 kg
Answer: A. 1 kg = 2.2 lbs. 180 ÷ 2.2 = 81.818, rounded to 81.6 kg.
12. The physician orders 500 mg of a medication. The available tablet is 250 mg. How
many tablets will you administer?
A. 1 tablet
B. 1.5 tablets
