Antiarrhythmic Drugs Mechanisms, Indications, and Precautions verified questions and
solution A+ grade
Quinidine (Class IA) - -It blocks sodium channels, slowing conduction and prolonging
repolarization/action-potential duration.
Quinidine Indications - -SVT, Atrial fibrillation/flutter, Ventricular arrhythmias.
Quinidine Precautions - -Hypotension, heart failure.
Quinidine Administration - -PO.
Tocainide (Class IB) - -It blocks sodium channels and is particularly effective in ventricular
tissue, especially abnormal/ischemic ventricular tissue.
Tocainide Indications - -Ventricular arrhythmias.
Tocainide Precautions - -Heart block, SA node dysfunction.
Tocainide Administration - -PO.
Propafenone (Class IC) - -It strongly blocks sodium channels, markedly slowing
conduction with relatively little effect on repolarization.
Propafenone Indications - -SVT, Atrial fibrillation/flutter.
, Propafenone Precautions - -Heart failure, heart block.
Propafenone Administration - -PO, IV.
Procainamide (Class IA) - -It blocks sodium channels, slowing conduction and prolonging
repolarization/action-potential duration.
Procainamide Indications - -SVT, Atrial fibrillation/flutter, Ventricular arrhythmias.
Procainamide Precautions - -SLE, hypotension.
Procainamide Administration - -IV, PO.
Mexiletine (Class IB) - -It blocks sodium channels and is particularly effective in
ventricular tissue, especially abnormal/ischemic ventricular tissue.
Mexiletine Indications - -Ventricular arrhythmias.
Mexiletine Precautions - -Heart block, liver disease.
Mexiletine Administration - -PO.
Moricizine (Class IC) - -It strongly blocks sodium channels, markedly slowing conduction
with relatively little effect on repolarization.
Moricizine Indications - -Ventricular arrhythmias.
solution A+ grade
Quinidine (Class IA) - -It blocks sodium channels, slowing conduction and prolonging
repolarization/action-potential duration.
Quinidine Indications - -SVT, Atrial fibrillation/flutter, Ventricular arrhythmias.
Quinidine Precautions - -Hypotension, heart failure.
Quinidine Administration - -PO.
Tocainide (Class IB) - -It blocks sodium channels and is particularly effective in ventricular
tissue, especially abnormal/ischemic ventricular tissue.
Tocainide Indications - -Ventricular arrhythmias.
Tocainide Precautions - -Heart block, SA node dysfunction.
Tocainide Administration - -PO.
Propafenone (Class IC) - -It strongly blocks sodium channels, markedly slowing
conduction with relatively little effect on repolarization.
Propafenone Indications - -SVT, Atrial fibrillation/flutter.
, Propafenone Precautions - -Heart failure, heart block.
Propafenone Administration - -PO, IV.
Procainamide (Class IA) - -It blocks sodium channels, slowing conduction and prolonging
repolarization/action-potential duration.
Procainamide Indications - -SVT, Atrial fibrillation/flutter, Ventricular arrhythmias.
Procainamide Precautions - -SLE, hypotension.
Procainamide Administration - -IV, PO.
Mexiletine (Class IB) - -It blocks sodium channels and is particularly effective in
ventricular tissue, especially abnormal/ischemic ventricular tissue.
Mexiletine Indications - -Ventricular arrhythmias.
Mexiletine Precautions - -Heart block, liver disease.
Mexiletine Administration - -PO.
Moricizine (Class IC) - -It strongly blocks sodium channels, markedly slowing conduction
with relatively little effect on repolarization.
Moricizine Indications - -Ventricular arrhythmias.
