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PMHNP Exam Reported Questions | Verified Answers & Detailed Rationales | Psychiatric-Mental Health Nurse Practitioner Board Exam Prep | Grade A+ | 2026–2027

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Prepare for the PMHNP Psychiatric-Mental Health Nurse Practitioner Certification Exam with reported-question style practice material, verified answers, and detailed rationales covering psychiatric assessment, DSM-5-TR diagnostic concepts, neurobiology, psychopharmacology, antidepressants, antipsychotics, mood stabilizers, anxiety and trauma-related disorders, psychotic and mood disorders, substance use disorders, psychotherapy, suicide risk assessment, crisis intervention, ethics, legal principles, research, statistics, and advanced psychiatric nursing practice. Designed for focused PMHNP board exam review and clinical reasoning preparation.

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PMHNP Exam Reported Questions - Verified Answers & Detailed Rationales

What is dissemination? Getting the research information out to those who need to know it!

Publication - highest level
Presenting at National Conference
Presenting at Local Conference
Journal Club where one person reviews an article


What does a 17 on MMSE mean? Moderate cognitive impairment




What is Tegretol in the CYP450 system? Inducer -->will lower dose of Lamictal and BCP's




What do BCP's do to Lamictal? Inducer - will lower dose of Lamictal




What is a Type I research error? There IS a difference but you say there isn't a difference.




What is a Type II research error? There is NO difference but you say there is a difference.




What is pseudo-dementia? Cognitive impairment secondary to depression that clears when treated in the
elderly. Dementia won't improve.



Is it normal for a 1 month old to have a palmar grasp? Yes.




What is a drug 1/2 life? The time it takes for 50% of a drug to be eliminated from the body.




What 3 atypicals can be used with teens? Zyprexa, Abilify, Seroquel - low doses




What is a risk of using Tramadol? Serotonin Syndrome as it is very serotonergic.




What is the allele seen in Asians that increase the risk of HLAB-1502
SJS?



When might you see toxic epidermal necrolysis? With worsening of SJS




How many generations do you include for a genogram? 1st degree - mother, father, siblings
2nd degree - grandparents & cousins
3rd degree -

, PMHNP Exam Reported Questions - Verified Answers & Detailed Rationales
What does messenger RNA code for? Amino Acids




What is epigenetics? Factors that affect genes - environmental, smoking, stress, etc...




What part of the brain is involved with OCD? Basal Ganglia
Occipito-Frontal



What happens to the brain during adolescence? Dendritic pruning
Emotions are controlled by amygdala
By adulthood, PFC involved as well


When do males typically present with schizophrenia? 10-25 yo




When do females typically present with schizophrenia? 25-35 yo




What does Erythromycin to trileptal? You will need to decreases the level because Trileptal(inducer) and erythromycin is
a inhibitor



ACE Inhibitors are the drug of choice for what? Heart Failure
HTN



What are some psychiatric side effects seen with some Leukotriene receptor agonists - singulair, accolade, zyflo = agitation, aggression,
asthma drugs anxiety, hallucinations, depression, insomnia, SI, tremor



What should you watch for with Tegretol? Agranulocytosis and Hyponatremia




What are the 3 CK muscle enzyme tests? CKBB, CKMM, CKMB




Which one of the 3 muscle enzymes are related to cardiac CKMB
muscle damage?



What is the risk of a seriously elevated CKMB? Polymyositis
Rhabdo



What is a normal CKMB? 0.3 mcg/L




What psychoactives does Detrol interact with? Topamax
KCL
Zonegran

, PMHNP Exam Reported Questions - Verified Answers & Detailed Rationales
What CN are you assessing when you have the patient CN XI - Spinal Accessory
shrug their shoulders?



What do you see in labs with HIV & Dementia? CD4 <200
Viral Load is high
<20% get it with antiretroviral treatment


What is the scoring with the Beck Depression Inventory? Self-Report - 0-63
0-13 - minimal
14-19 - mild
20-28 - moderate
29-63 - severe


What is sensitivity? Helps rule-out disease = True Positive = Snout




What is specificity? Helps rule-in disease = True Negative = Spin




What does a sed rate measure? Inflammation (ESR - Erythrocyte Sedimentation Rate) = distance in mm RBC's have
descended in 1 hour.



What is a normal sed rate or ESR? 0-22 males
0-29 females



What is a retic count? Measures % of reticulocytes in blood (immature RBC's) Indicates whether enough
RBC's are being produced by bone marrow.



What does a decreased retic count indicate? Anemia - acute or chronic bleeding




What does an increased retic count indicate? Bone marrow disorder or Vitamin Deficiency




What does an abnormal retic ount indicate in general? Doesn't diagnose anything. First step is ID source of the issue.




What happens when you mix tegretol and macrolides? Increase tegretol levels.




What happens if a pregnant women takes Accutane? Birth defects.




What labs do you get with RA? Sed rate, RF, ANA, C reactive protein, CBC, CMP, CRP - helps confirm diagnosis.
CRP and ESR are both increased in RA but NOT in osteoarthritis.



Where does the NP Code of Ethics come from? ANA

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