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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has
been prescribed oral paroxetine hydrochloride. What is the
expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the
body, circulated through the bloodstream to their sites of action in
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various body tissues, and eventually eliminated from the body.
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Curative agents are given to cure a disease process. In this case,
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paroxetine hydrochloride will control the symptoms but not cure the
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disorder. Drugs with local effects, such as sunscreen and local
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anesthetics, act mainly at the site of application. Paroxetine
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hydrochloride is not administered parenterally. Parenteral agents are
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administered subcutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1
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NAT: Client Needs: Physiological Integrity: Pharmacological
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and Parenteral Therapies TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally
occurring
substance that has been cheGmRicAalDlyEmSoBdOifOieSd.TWhaOt Mis
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another name for this type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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occurring substances that have been chemically modified. Synthetic
drugs are more standardized in their chemical characteristics, more
consistent in their effects, and less likely to produce allergic
reactions. Biotechnology drugs involve manipulating DNA and RNA
and recombining genes into hybrid molecules that can be inserted
into living organisms. Prototype drugs are the first drug of a
particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological
and Parenteral Therapies TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE