Immunology Exam 3 - Exam Questions & Verified Answers
What chemokine is produced by lymph node stromal cells, CCL21
starting the process of cellular recruitment into the lymph
node?
Where do we find the fallicular dendric cells? follicule
Diapedesis is the process of the T cell moving between the Chemokine Gradient
endothelial cells. This process is mediated by...
Naive T cells enter lymph nodes via endotheial cells call Selectins
HEVs. The first stage of entry is "rolling" along the HEVs.
What on the surface of the T cell stimulates the "rolling?"
What chemical in the blood attracts T cells out of the lymph S1P
node?
What chemokine receptor is expressed on activated CCR7
Dendritic cells that causes them to migrate to the lymph
node?
When do dendritic cells (DC) express the most B7 on the Activated DC's in the lymph node
surface of their cells?
When do dendritic cells (DC) express the most phagocytic Resting DC's in the tissue
receptors like Dectin-1 and DC-SIGN?
Select the statment below that is incorrect about antigen All are correct
presentation. dendritic cells present antigens to activate naive t cells
macrophages present antigens to become activated
b cells present antigens to retrieve t cell help
epithelial cells present antigens so they can die if infected
When a T cell activates it starts to express both IL-2 and proliferate
the alpha subunit of the IL-2 receptor. The dual expression
of these two proteins causes the T cell to...
cytokines differentiation
MHC/ antigen activation
B7 survival
A naive T cell exposed to IL-4 when activated by a Th2
dendritic cell in a lymph node will differentiate into a...
Stuvia 2026-2027 | Latest Version
, Immunology Exam 3 - Exam Questions & Verified Answers
TH1 cell secrete __________ in order to activate resting IFN-γ
macrophage.
Treg cell secrete _________ in order to supress the IL-10
activity of other effector T cells
T cell polarity is governed by the fact the cytokines of one suppresses the differentiation of TH2 cells
type of T cell prevent other types of T cells from
developing. An example of this is that TH1 cell produce
IFN-γ. IFN-γ...
Select to co-stimulation complex between a TH1 cell and CD40 and CD40 ligand
Macrophage.
How do activated macrophage kill intracellular pathogens? Production of oxygen radicals (oxidative bursts)
What type of effector T cell is required for control of a TH1 cells
Leishmania major infection in mice?
What type of pathogen specific T cells lead to lepromatious TH2 cells
lepracy?
You wish to study lepromatious leprosy in 9 banded Anti-IFN-gmma
armadillos (the only other animal that gets infected by
Mycobacterium leprae). Select the antibody you will inject
the test animals with to ensure they develop lepromatious
leprosy.
How do CD8+ T cells kill antigen presenting cells? Apoptosis
When a naive CD8+ T cell becomes activated for the first IL-2
time it will secrete this cytokine and its receptor in order to
proliferate.
Select all of the proteins that would be in the cSMAC of a CD8, TCR, MHC 1
cytotoxic T cell interacting with an epithelial cell.
Intrinsic apoptosis is marked by this protein in the cytosol. cytochrome C
Granzymes are..... serine proteases
When granzyme is translocated into the cytosol, via BID
perforin, it will cleave this protein in order to stimulate
apoptosis.
Stuvia 2026-2027 | Latest Version
What chemokine is produced by lymph node stromal cells, CCL21
starting the process of cellular recruitment into the lymph
node?
Where do we find the fallicular dendric cells? follicule
Diapedesis is the process of the T cell moving between the Chemokine Gradient
endothelial cells. This process is mediated by...
Naive T cells enter lymph nodes via endotheial cells call Selectins
HEVs. The first stage of entry is "rolling" along the HEVs.
What on the surface of the T cell stimulates the "rolling?"
What chemical in the blood attracts T cells out of the lymph S1P
node?
What chemokine receptor is expressed on activated CCR7
Dendritic cells that causes them to migrate to the lymph
node?
When do dendritic cells (DC) express the most B7 on the Activated DC's in the lymph node
surface of their cells?
When do dendritic cells (DC) express the most phagocytic Resting DC's in the tissue
receptors like Dectin-1 and DC-SIGN?
Select the statment below that is incorrect about antigen All are correct
presentation. dendritic cells present antigens to activate naive t cells
macrophages present antigens to become activated
b cells present antigens to retrieve t cell help
epithelial cells present antigens so they can die if infected
When a T cell activates it starts to express both IL-2 and proliferate
the alpha subunit of the IL-2 receptor. The dual expression
of these two proteins causes the T cell to...
cytokines differentiation
MHC/ antigen activation
B7 survival
A naive T cell exposed to IL-4 when activated by a Th2
dendritic cell in a lymph node will differentiate into a...
Stuvia 2026-2027 | Latest Version
, Immunology Exam 3 - Exam Questions & Verified Answers
TH1 cell secrete __________ in order to activate resting IFN-γ
macrophage.
Treg cell secrete _________ in order to supress the IL-10
activity of other effector T cells
T cell polarity is governed by the fact the cytokines of one suppresses the differentiation of TH2 cells
type of T cell prevent other types of T cells from
developing. An example of this is that TH1 cell produce
IFN-γ. IFN-γ...
Select to co-stimulation complex between a TH1 cell and CD40 and CD40 ligand
Macrophage.
How do activated macrophage kill intracellular pathogens? Production of oxygen radicals (oxidative bursts)
What type of effector T cell is required for control of a TH1 cells
Leishmania major infection in mice?
What type of pathogen specific T cells lead to lepromatious TH2 cells
lepracy?
You wish to study lepromatious leprosy in 9 banded Anti-IFN-gmma
armadillos (the only other animal that gets infected by
Mycobacterium leprae). Select the antibody you will inject
the test animals with to ensure they develop lepromatious
leprosy.
How do CD8+ T cells kill antigen presenting cells? Apoptosis
When a naive CD8+ T cell becomes activated for the first IL-2
time it will secrete this cytokine and its receptor in order to
proliferate.
Select all of the proteins that would be in the cSMAC of a CD8, TCR, MHC 1
cytotoxic T cell interacting with an epithelial cell.
Intrinsic apoptosis is marked by this protein in the cytosol. cytochrome C
Granzymes are..... serine proteases
When granzyme is translocated into the cytosol, via BID
perforin, it will cleave this protein in order to stimulate
apoptosis.
Stuvia 2026-2027 | Latest Version
