And Answers SNHU
Q1. Stimulation of beta-1 adrenergic receptors primarily produces
which effect?
A) Bronchodilation
B) Increased heart rate and myocardial contractility
C) Pupillary constriction
D) Reduced renin secretion
Correct Answer: B) Increased heart rate and myocardial contractility
Rationale: Beta-1 receptors are concentrated in the heart and increase
chronotropy and contractility when stimulated.
Q2. Which effect is most strongly associated with beta-2 receptor
activation?
A) Increased gastrointestinal motility
B) Bradycardia
C) Peripheral vasoconstriction
D) Bronchial smooth-muscle relaxation
Correct Answer: D) Bronchial smooth-muscle relaxation
Rationale: Beta-2 stimulation relaxes bronchial smooth muscle and is an
important mechanism of bronchodilation.
Q3. Which medication class blocks the effects of norepinephrine at
alpha-1 receptors?
A) Alpha-1 adrenergic antagonists
B) Muscarinic agonists
C) Beta-2 agonists
D) Cholinesterase inhibitors
Correct Answer: A) Alpha-1 adrenergic antagonists
Rationale: Alpha-1 blockade reduces vascular smooth-muscle contraction
and can lower peripheral vascular resistance.
Q4. A major adverse effect associated with alpha-1 blockers is which
finding?
A) Severe hyperglycemia
B) Bronchospasm
C) Orthostatic hypotension
D) Hyperkalemia
Correct Answer: C) Orthostatic hypotension
Rationale: Peripheral vasodilation can impair blood-pressure maintenance
when the patient stands.
, Q5. Which patient requires particular caution before receiving a
nonselective beta blocker?
A) Patient with seasonal allergic rhinitis
B) Patient with asthma and active bronchospasm
C) Patient with uncomplicated constipation
D) Patient with iron-deficiency anemia
Correct Answer: B) Patient with asthma and active bronchospasm
Rationale: Nonselective beta blockers antagonize beta-2 receptors and may
worsen bronchoconstriction.
Q6. Abrupt discontinuation of long-term beta-blocker therapy can
produce which complication?
A) Permanent hypoglycemia
B) Renal failure in every patient
C) Severe neutropenia
D) Rebound tachycardia, hypertension, or myocardial ischemia
Correct Answer: D) Rebound tachycardia, hypertension, or myocardial
ischemia
Rationale: Chronic beta blockade can increase adrenergic sensitivity,
making abrupt withdrawal potentially hazardous.
Q7. Which physiologic effect is expected from muscarinic receptor
stimulation?
A) Increased gastrointestinal motility and secretions
B) Bronchodilation
C) Tachycardia
D) Urinary retention
Correct Answer: A) Increased gastrointestinal motility and secretions
Rationale: Parasympathetic muscarinic stimulation promotes secretions and
smooth-muscle activity within several organ systems.
Q8. Which adverse-effect pattern is most characteristic of an
antimuscarinic medication?
A) Diarrhea and salivation
B) Bradycardia and sweating
C) Dry mouth, constipation, urinary retention, and blurred vision
D) Bronchial secretions and miosis
Correct Answer: C) Dry mouth, constipation, urinary retention, and blurred
vision
Rationale: Muscarinic blockade reduces secretions and smooth-muscle
activity and can impair accommodation and bladder emptying.