Barkley Dermatology Exam PRACTICE
QUESTIONS
|ORIGINAL QUESTIONS &
ANSWERS |DETAILED
RATIONALES |HINTED
COMPLETE EXAM PREP
GRADED A+*INSTANT
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1.
A 24-year-old woman presents with open and closed
comedones, inflammatory papules, and pustules on her face.
Which diagnosis is most likely?
A. Rosacea
B. Seborrheic dermatitis
C. Acne vulgaris
D. Perioral dermatitis
Rationale: Acne vulgaris is characterized by comedones,
papules, pustules, and sometimes nodules caused by follicular
plugging, sebum production, inflammation, and
Cutibacterium acnes.
,2.
Which topical medication is considered first-line therapy for
comedonal acne?
A. Topical mupirocin
B. Topical retinoid
C. Topical ketoconazole
D. Topical hydrocortisone
Rationale: Topical retinoids normalize follicular keratinization
and are particularly effective for comedonal acne.
3.
A patient with moderate inflammatory acne is prescribed
benzoyl peroxide. What is its primary antimicrobial target?
A. Candida species
B. Staphylococcus aureus only
C. Cutibacterium acnes
D. Malassezia species
Rationale: Benzoyl peroxide has antibacterial activity against
C. acnes and helps reduce antibiotic resistance when used
with topical antibiotics.
4.
Which adverse effect is most commonly associated with
topical tretinoin?
A. Hyperkalemia
B. Alopecia
C. Skin irritation and photosensitivity
D. Severe neutropenia
,Rationale: Topical retinoids commonly cause erythema,
dryness, peeling, irritation, and increased photosensitivity.
5.
A patient with severe nodulocystic acne has failed
conventional therapy. Which medication may be considered?
A. Permethrin
B. Isotretinoin
C. Terbinafine
D. Acyclovir
Rationale: Oral isotretinoin is highly effective for severe
nodular acne and acne that is resistant to standard therapy.
6.
Which laboratory abnormality is particularly important to
monitor in patients taking systemic isotretinoin?
A. Serum calcium only
B. Triglycerides and liver enzymes
C. Serum amylase only
D. Troponin
Rationale: Isotretinoin can cause hypertriglyceridemia and
elevations in hepatic transaminases.
7.
A woman taking isotretinoin becomes pregnant. What is the
major concern?
A. Maternal hypothyroidism
B. Severe fetal teratogenicity
, C. Neonatal hypoglycemia only
D. Fetal macrosomia
Rationale: Isotretinoin is a potent teratogen associated with
severe congenital abnormalities.
8.
A patient has facial erythema, telangiectasias, and recurrent
inflammatory papules without comedones. What is the most
likely diagnosis?
A. Acne vulgaris
B. Rosacea
C. Tinea faciei
D. Psoriasis
Rationale: Rosacea commonly causes central facial erythema,
flushing, telangiectasias, and inflammatory papules or
pustules without comedones.
9.
Which finding is particularly suggestive of ocular rosacea?
A. Retinal detachment
B. Blepharitis and recurrent ocular irritation
C. Hyphema
D. Cataract
Rationale: Ocular rosacea may cause blepharitis, conjunctival
irritation, dry eyes, and recurrent chalazia.
10.
Which environmental factor commonly exacerbates rosacea?
QUESTIONS
|ORIGINAL QUESTIONS &
ANSWERS |DETAILED
RATIONALES |HINTED
COMPLETE EXAM PREP
GRADED A+*INSTANT
DOWNLOAD PDF
1.
A 24-year-old woman presents with open and closed
comedones, inflammatory papules, and pustules on her face.
Which diagnosis is most likely?
A. Rosacea
B. Seborrheic dermatitis
C. Acne vulgaris
D. Perioral dermatitis
Rationale: Acne vulgaris is characterized by comedones,
papules, pustules, and sometimes nodules caused by follicular
plugging, sebum production, inflammation, and
Cutibacterium acnes.
,2.
Which topical medication is considered first-line therapy for
comedonal acne?
A. Topical mupirocin
B. Topical retinoid
C. Topical ketoconazole
D. Topical hydrocortisone
Rationale: Topical retinoids normalize follicular keratinization
and are particularly effective for comedonal acne.
3.
A patient with moderate inflammatory acne is prescribed
benzoyl peroxide. What is its primary antimicrobial target?
A. Candida species
B. Staphylococcus aureus only
C. Cutibacterium acnes
D. Malassezia species
Rationale: Benzoyl peroxide has antibacterial activity against
C. acnes and helps reduce antibiotic resistance when used
with topical antibiotics.
4.
Which adverse effect is most commonly associated with
topical tretinoin?
A. Hyperkalemia
B. Alopecia
C. Skin irritation and photosensitivity
D. Severe neutropenia
,Rationale: Topical retinoids commonly cause erythema,
dryness, peeling, irritation, and increased photosensitivity.
5.
A patient with severe nodulocystic acne has failed
conventional therapy. Which medication may be considered?
A. Permethrin
B. Isotretinoin
C. Terbinafine
D. Acyclovir
Rationale: Oral isotretinoin is highly effective for severe
nodular acne and acne that is resistant to standard therapy.
6.
Which laboratory abnormality is particularly important to
monitor in patients taking systemic isotretinoin?
A. Serum calcium only
B. Triglycerides and liver enzymes
C. Serum amylase only
D. Troponin
Rationale: Isotretinoin can cause hypertriglyceridemia and
elevations in hepatic transaminases.
7.
A woman taking isotretinoin becomes pregnant. What is the
major concern?
A. Maternal hypothyroidism
B. Severe fetal teratogenicity
, C. Neonatal hypoglycemia only
D. Fetal macrosomia
Rationale: Isotretinoin is a potent teratogen associated with
severe congenital abnormalities.
8.
A patient has facial erythema, telangiectasias, and recurrent
inflammatory papules without comedones. What is the most
likely diagnosis?
A. Acne vulgaris
B. Rosacea
C. Tinea faciei
D. Psoriasis
Rationale: Rosacea commonly causes central facial erythema,
flushing, telangiectasias, and inflammatory papules or
pustules without comedones.
9.
Which finding is particularly suggestive of ocular rosacea?
A. Retinal detachment
B. Blepharitis and recurrent ocular irritation
C. Hyphema
D. Cataract
Rationale: Ocular rosacea may cause blepharitis, conjunctival
irritation, dry eyes, and recurrent chalazia.
10.
Which environmental factor commonly exacerbates rosacea?
