Lippincott Illustrated Reviews: Pharmacology, 8th Edition by Karen Whalen
TEST BANK
,Chapter 1: Pharmacokinetics
MULTIPLE CHOICE
1. Which drugs will go through a pharmaceutic phase after it is administered?
a. Intramuscular cephalosporins
b. Intravenous vasopressors
c. Oral analgesics
d. Subcutaneous antiglycemics
ANS: C
When drugs are administered parenterally, there is no pharmaceutic phase, which
occurs when a drug becomes a solution that can cross the biologic membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Assessment
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
2. The nurse is preparing to administer an oral medication and wants to ensure
a rapid drug action. Which form of the medication will the nurse administer?
a. Capsule
b. Enteric-coated pill
c. Liquid suspension
d. Tablet
ANS: C
Liquid drugs are already in solution, which is the form necessary for
absorption in the GI tract. The other forms must disintegrate into small
particles and then dissolve before being absorbed.
DF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 1 of 507
,3. TheKnurseKisKteachingKaKpatientKwhoKwillKbeKdischargedKhomeKwithKaKprescriptionKforKanKenteri
c-KcoatedKtablet.KWhichKstatementKbyKtheKpatientK indicatesKunderstandingKofKtheKteaching?
a. IKmayKcrushKtheKtabletKandKputKitKinKapplesauceKtoKimproveKabsorption.
b. IKshouldK consumeKacidicKfoodsKtoKenhanceKabsorptionKofKthisKmedication.
c. IK shouldK expectK aKdelayKinKonsetK ofKtheKdrugsKeffectsKafterKtakingKtheKtablet.
d. IKshouldKtakeKthisKmedicationKwithKhigh-
fatKfoodsKtoKimproveKitsKaction.KANS:KC
Enteric-
coatedKtabletsKresistKdisintegrationKinKtheKacidicKenvironmentKofKtheKstomachKandKdisintegrateKw
henKtheyKreachKtheKsmallKintestine.KThereKisKusuallyKsomeKdelayKinKonsetKofKactionsKafterKtakingKt
heseKmedications.KEnteric-
coatedKtabletsKshouldKnotKbeKcrushedKorKchewed,KwhichKwouldKalterKtheKtimeKandKlocationKofKabs
orption.KAcidicKfoodsKwillKnotKenhanceKtheKabsorptionKofKtheKmedication.KTheKpatientKshouldKnot
toKeatKhigh-fatKfoodKbeforeKingestingKanKenteric-coatedKtablet,KbecauseKhigh-
K
fatKfoodsKdecreaseKtheKabsorptionKrate.
DIF:KCOGNITIVEKLEVEL:KApplyingK(Application)KREF:KdmK3KT
OP:KNURSINGKPROCESS:KNursingKIntervention
MSC:KNCLEX:KPhysiologicalKIntegrity:KPharmacologicalKandKParenteralKTherapies
4. AKpatientKwhoKisKnewlyKdiagnosedKwithKtypeK1KdiabetesKmellitusKasksKwhyKinsulinKmustKbeK
givenKbyKsubcutaneousKinjectionKinsteadKofKbyKmouth.KTheKnurseKwillKexplainKthatKthisKisKbecau
se
a. absorptionKisK diminishedK byKtheKfirst-passKeffectsKinKtheKliver.
b. absorptionKisKfasterKwhenKinsulinKisKgivenKsubcutaneously.
c. digestiveKenzymesKinKtheKgastrointestinalKtractKpreventKabsorption.
d. theKoralKformKisKlessKpredictableKwithKmoreKadverseKeffects
.KANS:KC
Insulin,KgrowthKhormones,KandKotherKprotein-
basedKdrugsKareKdestroyedKinKtheKsmallKintestineKbyKdigestiveKenzymesKandKmustKbeKgivenKparen
terally.KBecauseKinsulinKisKdestroyedKbyKdigestiveKenzymes,KitKwouldKnotKmakeKitKtoKtheKliverKfor
metabolismKwithKaKfirst-
K
passKeffect.KSubcutaneousKtissueKhasKfewerKbloodKvessels,KsoKabsorptionKisKslowerKinKsuchKtissue
.KInsulinKisKgivenKsubcutaneouslyKbecauseKitKisKdesirableKtoKhaveKitKabsorbKslowly.
DIF:KCOGNITIVEKLEVEL:KUnderstandingK(Comprehension)KREF:KdmK3KT
PageK 2K ofK 507
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, OP:KNURSINGKPROCESS:KNursingKIntervention:KPatientKTeaching
MSC:KNCLEX:KPhysiologicalKIntegrity:KPharmacologicalKandKParenteralKTherapies
PageK 3K ofK 507
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