NSG 555 / NSG555 Quiz 4 (v2):
Nurse Practitioners in Primary Care
II | Latest - Wilkes
Question:
Scleroderma limited dz
Answer:
CREST syndrome
skin thickening/hardening confined to face, neck, and digital extremities
Calcinosis
Raynaud phenomenon
Esophageal motility disorder
Sclerodactyly
Telangiectasia
(higher risk for losing fingers d/t ischemia and pulmonary HTN)
,Question:
Scleroderma diffuse dz
Answer:
widespread thickening of skin, with areas of increased pigmentation and
depigmentation
Question:
Diffuse scleroderma clinical presentation
Answer:
Common early:
polyarthralgia
weight loss
malaise
Other:
skin changes involving trunk, proximal extremities
subcutaneous edema associated with pruritus
Skin becomes thickened and hidebound, loses normal folds
Telangiectasia, pigmentation, depigmentation common
Ulceration of fingertips
Tendon friction rubs over forearms and shins
Restrictive lung dz
Cardiac abnormalities
Renal crisis
,Question:
Scleroderma systemic features
Answer:
Gastroesophageal reflux
GI hypomotility
Pulmonary fibrosis
Pulmonary HTN
Renal involvement
Question:
Scleroderma presentation
Answer:
-raynaud phenomenon and antinuclear antibodies are present in virtually
all patients
, Question:
Scleroderma labs
Answer:
Mild anemia (hemolytic)
Normal ESR
Mild proteinuria
ANA positive and high
anti-SCL-70 only 20-30% and poor prognosis
Anticentromere antibodies in 50% with limited dz
Anti-RNA polymerase III antibodies 10-20% assoc w/ rapid dz, renal crisis,
higher risk of cancers, esp breast ca
Question:
Differentiate scleroderma and sclerederma
Answer:
Scleroderma assoc w/ diabetes or infection
Skin thickening of the posterior neck, shoulders, upper back
Spares the fingers!
Nurse Practitioners in Primary Care
II | Latest - Wilkes
Question:
Scleroderma limited dz
Answer:
CREST syndrome
skin thickening/hardening confined to face, neck, and digital extremities
Calcinosis
Raynaud phenomenon
Esophageal motility disorder
Sclerodactyly
Telangiectasia
(higher risk for losing fingers d/t ischemia and pulmonary HTN)
,Question:
Scleroderma diffuse dz
Answer:
widespread thickening of skin, with areas of increased pigmentation and
depigmentation
Question:
Diffuse scleroderma clinical presentation
Answer:
Common early:
polyarthralgia
weight loss
malaise
Other:
skin changes involving trunk, proximal extremities
subcutaneous edema associated with pruritus
Skin becomes thickened and hidebound, loses normal folds
Telangiectasia, pigmentation, depigmentation common
Ulceration of fingertips
Tendon friction rubs over forearms and shins
Restrictive lung dz
Cardiac abnormalities
Renal crisis
,Question:
Scleroderma systemic features
Answer:
Gastroesophageal reflux
GI hypomotility
Pulmonary fibrosis
Pulmonary HTN
Renal involvement
Question:
Scleroderma presentation
Answer:
-raynaud phenomenon and antinuclear antibodies are present in virtually
all patients
, Question:
Scleroderma labs
Answer:
Mild anemia (hemolytic)
Normal ESR
Mild proteinuria
ANA positive and high
anti-SCL-70 only 20-30% and poor prognosis
Anticentromere antibodies in 50% with limited dz
Anti-RNA polymerase III antibodies 10-20% assoc w/ rapid dz, renal crisis,
higher risk of cancers, esp breast ca
Question:
Differentiate scleroderma and sclerederma
Answer:
Scleroderma assoc w/ diabetes or infection
Skin thickening of the posterior neck, shoulders, upper back
Spares the fingers!
