GBIO 200
CELL BIOLOGY
FINAL - 200Q
Cumulative review of cell foundations, gene expression, protein
trafficking, metabolism, cell division, membranes, transport, and
signaling
200 A-D FULL
ORIGINAL QUESTIONS ANSWER CHOICES RATIONALES
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Concept recall + application questions
Immediate answers with concise explanations
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,PASSPOINT PRO | GBIO 200 CELL BIOLOGY FINAL - 200Q
HOW TO USE THIS PRACTICE SET
Format: Each item includes four answer choices followed immediately by the correct answer and an explanation. Best use:
Complete a first pass without reading the answer, then use each rationale to repair weak concepts. Coverage: Cumulative review
of cell foundations, gene expression, protein trafficking, metabolism, cell division, membranes, transport, and signaling.
QUESTIONS 1-25
1 Which option is most accurately defined as a nucleic acid building block consisting of a sugar,
phosphate group, and nitrogenous base?
A. eukaryotic cell
B. nucleotide
C. cholesterol
D. tertiary protein structure
Answer: B
Explanation: Nucleotide is correct because it is a nucleic acid building block consisting of a sugar, phosphate group, and nitrogenous
base. DNA polymerase adds a sugar-phosphate-base unit to a growing DNA strand. This match is more specific than the related
alternatives, which describe different structures, molecules, or processes.
2 A cell undergoes the following change: Lower availability would reduce the cell's capacity to drive many
endergonic processes. Which target was most likely altered?
A. ATP
B. triglyceride
C. monosaccharide
D. tertiary protein structure
Answer: A
Explanation: Atp is the best match. It is adenosine triphosphate, a nucleotide that couples energy-releasing processes to
energy-requiring cellular work, so the stated consequence follows directly when its function is changed. The other options can influence
cellular behavior, but they do not most directly predict this specific outcome.
3 An animal membrane remains functional across temperature changes because a sterol buffers
membrane fluidity. Which concept most directly explains this observation?
A. glycogen
B. phospholipid
C. cholesterol
D. dehydration reaction
Answer: C
Explanation: Cholesterol best explains the observation because it is a sterol that modulates animal membrane fluidity and also serves as
a precursor for steroid molecules. The scenario is a direct application of that function or mechanism. The distractors are related
cell-biology concepts but do not account for the key feature described.
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,PASSPOINT PRO | GBIO 200 CELL BIOLOGY FINAL - 200Q
4 Which concept is most directly associated with this predicted consequence: Degrading it prevents
translation of the encoded protein.?
A. anticodon
B. mRNA
C. codon
D. A site
Answer: B
Explanation: Mrna is the best match. It is messenger RNA that carries coding information from DNA to ribosomes, so the stated
consequence follows directly when its function is changed. The other options can influence cellular behavior, but they do not most directly
predict this specific outcome.
5 Identify the concept described here: a bacterial gene-regulatory system that promotes lactose-use
genes when lactose is available and glucose is limited.
A. lac operon
B. regulated secretion
C. enhancer
D. clathrin-coated vesicle
Answer: A
Explanation: Lac operon is correct because it is a bacterial gene-regulatory system that promotes lactose-use genes when lactose is
available and glucose is limited. Bacterial cells strongly express lactose-metabolism genes when lactose is present and glucose is scarce.
This match is more specific than the related alternatives, which describe different structures, molecules, or processes.
6 A selective perturbation causes this outcome: Loss of this polymer would weaken plant cell wall
structure. Which process or structure is the best match?
A. dehydration reaction
B. monosaccharide
C. cellulose
D. hydrolysis
Answer: C
Explanation: Cellulose is the best match. It is a beta-glucose polysaccharide that provides structural support in plant cell walls, so the
stated consequence follows directly when its function is changed. The other options can influence cellular behavior, but they do not most
directly predict this specific outcome.
7 Which term-description pairing is correct?
A. facilitated diffusion - net movement of water across a selectively permeable membrane toward the side with lower water potential
or higher effective solute concentration
B. ion channel - passive movement down an electrochemical gradient through a membrane channel or carrier
C. osmosis - a selective membrane pore that permits ions to move rapidly down their electrochemical gradients
D. antiport - coupled transport in which two solutes move through one transporter in opposite directions
Answer: D
Explanation: The correct pairing is antiport with its defining feature: coupled transport in which two solutes move through one transporter
in opposite directions. A transporter exchanges intracellular hydrogen ions for extracellular sodium ions. The remaining pairs intentionally
mismatch a term with the description of a different concept.
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, PASSPOINT PRO | GBIO 200 CELL BIOLOGY FINAL - 200Q
8 Which description should be paired with smooth endoplasmic reticulum?
A. a ribonucleoprotein complex that translates mRNA into polypeptide
B. an ER region involved in lipid synthesis, detoxification, and calcium storage in specialized cells
C. an acidic organelle containing hydrolytic enzymes that digest macromolecules and worn-out cellular material
D. a double-membrane organelle that carries out major steps of aerobic ATP production in eukaryotic cells
Answer: B
Explanation: The correct description of smooth endoplasmic reticulum is that it is an ER region involved in lipid synthesis, detoxification,
and calcium storage in specialized cells. A liver cell expands an organelle network used for drug detoxification and lipid metabolism. The
other choices define different concepts and therefore do not fit this term.
9 A cell-cycle regulator accumulates, activates a kinase, and is later degraded. Which concept most
directly explains this observation?
A. p53
B. Rb protein
C. G2 phase
D. cyclin
Answer: D
Explanation: Cyclin best explains the observation because it is a regulatory protein whose concentration changes through the cell cycle
and activates specific cyclin-dependent kinases. The scenario is a direct application of that function or mechanism. The distractors are
related cell-biology concepts but do not account for the key feature described.
10 A receptor activates an enzyme that produces one soluble and one membrane-associated second
messenger. What is the best explanation for the finding?
A. phospholipase C
B. DAG
C. mTOR
D. signal amplification
Answer: A
Explanation: Phospholipase c best explains the observation because it is an effector enzyme that cleaves PIP2 to generate IP3 and
DAG. The scenario is a direct application of that function or mechanism. The distractors are related cell-biology concepts but do not
account for the key feature described.
11 Identify the concept described here: a rope-like cytoskeletal element that provides tensile strength and
mechanical stability.
A. microfilament
B. microtubule
C. intermediate filament
D. myosin
Answer: C
Explanation: Intermediate filament is correct because it is a rope-like cytoskeletal element that provides tensile strength and mechanical
stability. Epithelial cells resist stretching because of strong fibers linked to cell junctions. This match is more specific than the related
alternatives, which describe different structures, molecules, or processes.
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