WGU 785 FINAL EXAM COMPLETE STUDY
GUIDE, EXAM PREP, PRACTICE QUESTIONS
& ANSWERS | COMPREHENSIVE EXAM
REVIEW MATERIALS
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UPDATED QUESTIONS AND ANSWERS
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[EXAM• STUDY GUIDE • SUMMARY • ASSIGNMENT]
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, Hemophilia Pedigree - Father has hemophilia, mother does His daughters would be carriers. This is x-link recessive.
not. What is the outcome for their kids?
Autosomal: Autosomal: males and females equally affected.
Dominant: Dominant: non-carrier parents
polymerase chain reaction (PCR) The process of copying DNA in the lab. Uses Template DNA, Nucleotides (dNTPS), DNA
Polymerase, and DNA primers.
3 Steps of PCR 1. Denaturation: DNA is heated to 95C to separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and
add DNA polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building
a new DNA strand.
Base Excision Repair (BER) How you repair a mutation. BER is used to repair damage to a base caused by harmful
molecules. You remove the base that is damaged and replace it. BER removes a single
nucleotide
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: replication. DNA polymerase proofreads but sometimes a mismatch pair gets through.
MMR removes a large section of the nucleotides from the new DNA and DNA
polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? When a base is mismatched due to errors in replication. Such as G-T instead of G-C. DNA
polymerase comes by and fixes it.
What happens when DNA polymerase binds to DNA to make TRANSCRIPTION! DNA polymerase takes the individual nucleotides and matches them to
RNA? the parental sequences to ensure a correct pair. It must bind with RNA primer to work.
What is needed for DNA replication? DNA polymerase
Nonsense Mutation Change in 1 nucleotide produces a STOP codon Stop= nonsense because it is no more.
Silent Mutation Change in 1 nucleotide but codes for the same amino acid. Silent= the change doesn't
change the name of the protein
GUIDE, EXAM PREP, PRACTICE QUESTIONS
& ANSWERS | COMPREHENSIVE EXAM
REVIEW MATERIALS
| GRADED A+ | GUARANTEED SUCCESS
UPDATED QUESTIONS AND ANSWERS
100% VERIFIED EXAM PREP
[EXAM• STUDY GUIDE • SUMMARY • ASSIGNMENT]
A clean, organized resource designed for easy revision and reference.
QUICK • CLEAR • PROFESSIONAL
, Hemophilia Pedigree - Father has hemophilia, mother does His daughters would be carriers. This is x-link recessive.
not. What is the outcome for their kids?
Autosomal: Autosomal: males and females equally affected.
Dominant: Dominant: non-carrier parents
polymerase chain reaction (PCR) The process of copying DNA in the lab. Uses Template DNA, Nucleotides (dNTPS), DNA
Polymerase, and DNA primers.
3 Steps of PCR 1. Denaturation: DNA is heated to 95C to separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and
add DNA polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building
a new DNA strand.
Base Excision Repair (BER) How you repair a mutation. BER is used to repair damage to a base caused by harmful
molecules. You remove the base that is damaged and replace it. BER removes a single
nucleotide
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: replication. DNA polymerase proofreads but sometimes a mismatch pair gets through.
MMR removes a large section of the nucleotides from the new DNA and DNA
polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? When a base is mismatched due to errors in replication. Such as G-T instead of G-C. DNA
polymerase comes by and fixes it.
What happens when DNA polymerase binds to DNA to make TRANSCRIPTION! DNA polymerase takes the individual nucleotides and matches them to
RNA? the parental sequences to ensure a correct pair. It must bind with RNA primer to work.
What is needed for DNA replication? DNA polymerase
Nonsense Mutation Change in 1 nucleotide produces a STOP codon Stop= nonsense because it is no more.
Silent Mutation Change in 1 nucleotide but codes for the same amino acid. Silent= the change doesn't
change the name of the protein
